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Symposium II: BioMEMS─Materials and Devices

• 2011 MRS Fall Meeting & Exhibit

• November 28 - December 2, 2011
• Hynes Convention Center, Boston, MA
• Meeting Chairs: Cammy R. Abernathy, Paul V. Braun, Masashi Kawasaki, Kathryn J. Wahl

* Invited paper

 

8:30 AM *II1.1
Microfluidic Technology for Building and Handling 3D Tissue Structures.Shoji Takeuchi, Univ. of Tokyo, Tokyo, Japan; JST ERATO, Tokyo, Japan.

9:00 AM II1.2
A Polymeric 3D Artificial Compound Eye for Wide-Angle Imaging.Hansong Zeng and Yi Zhao; Biomedical Engineering Department, Ohio State University, Columbus, Ohio.

9:15 AM II1.3
Hybrid Silicon MEMS/Biogenic Silica Microfluidics Platform for Separating and Detecting Transport of Ions and Molecules. Kai-Chun Lin¹, B. Ramakrishna¹, Xiaofeng Wang² and Michael Goryll²; ¹School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, Arizona; ²School of Electrical, Computer and Energy Engineering, Arizona State University, Tempe, Arizona.

9:30 AM *II1.4
Neuroscience on a Chip.Albert Folch, Bioengineering, University of Washington, Seattle, Washington.

10:00 AM BREAK

10:30 AM *II1.5
Multipurpose Microfluidic Probes: Dipoles, Quadrupoles and Electrochemical Sensors for Studies with Cells and Tissue.David Juncker, Biomedical Engineering Department, McGill University, Montreal, Quebec, Canada.

11:00 AM *II1.6
Microfluidic Platforms for Study of 3D Cell Chemotaxis within Biomaterials. Amir Shamloo² and Sarah Heilshorn¹; ¹Materials Science & Engineering, Stanford University, Stanford, California; ²Mechanical Engineering, Stanford University, Stanford, California.

11:30 AM II1.7
A Microfluidic Assay for Measuring Electrical Conductivity of Gap Junction Channels.Cedric Bathany¹, Derek Beahm², Steve Besch², Frederick Sachs² and Susan Z. Hua^1,2; ¹Dept. of Mechanical & Aerospace Eng., SUNY Buffalo, Buffalo, New York; ²Department of Physiology and Biophysics, SUNY-Buffalo, Buffalo, New York.

11:45 AM II1.8 

Method for Efficient Droplet Extraction from Covered Droplet-in-Oil Electrowetting-on-Dielectric Devices.Haig Norian, Ioannis Kymissis and Kenneth Shepard; Columbia University, New York, New York.



 

1:30 PM *II2.1
Development of Electrochemiluminescence and Surface Plasmon Resonance-Based Immunosensors with Surface Accumulable Molecules.Ryoji Kurita, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan.

2:00 PM II2.2
Multiplexed, Enzyme-Free Pathogen Detection Using a DNA Nanobarcode Microfluidic Device.Roanna C. H. Ruiz¹, Mark R. Hartman², Hector E. Acaron², Thua N. N. Tran², Shawn J. Tan¹ and Dan Luo²; ¹Biomedical Engineering, Cornell University, Ithaca, New York; ²Biological and Environmental Engineering, Cornell University, Ithaca, New York. 

2:15 PM II2.3
Label-Free Biomolecule Detection in Nanowall Arrays.Takao Yasui^1,2, Noritada Kaji³, Yukihiro Okamoto², Manabu Tokeshi^1,2, Yasuhiro Horiike⁴ and Yoshinobu Baba^1,2,5; ¹Applied Chemistry, Nagoya University, Nagoya, Japan; ²FIRST Research Center for Innovative Nanobiodevice, Nagoya University, Nagoya, Japan; ³ERATO Higashiyama Live-Holonics Project, Nagoya University, Nagoya, Japan; ⁴National Institute for Materials Science, Tsukuba, Japan; ⁵National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu, Japan.

2:30 PM *II2.4
Plasmonic Metamaterials for Multi-Resonant Spectroscopy and High Resolution Optical Trapping.Hatice Altug, Arif Cetin, Mustafa Turkmen, Kai Chen, Serap Aksu, Ali Yanik and Alp Artar; Electrical and Computer, Boston University, Boston, Massachusetts.

3:00 PM BREAK

3:30 PM *II2.5
Microfluidics for Cell Sorting and Clinical Applications.Mehmet Toner, MassGeneral Hospital, Harvard Medical School, Charlestown, Massachusetts.

4:00 PM *II2.6
Immuno-Pillar Chips for Clinical Diagnosis.Manabu Tokeshi, Department of Applied Chemistry, Nagoya University, Nagoya, Japan; FIRST Research Center for Innovative Nanobiodevices, Nagoya University, Nagoya, Japan.

4:30 PM II2.7
On-Chip Diagnostic System for Circulating Tumor Cells.Jaehoon Chung, Huilin Shao, Ralph Weissleder and Hakho Lee; Center for Systems Biology, Massachusetts General Hospitals, Boston, Massachusetts.

4:45 PM II2.8
Cancer Cells in 3D Microenvironments: Individual and Collective Migration Behaviors.Ian Y. Wong^1,2, Daniel Irimia^1,2 and Mehmet Toner^1,2; ¹BioMEMS Resource Center, Massachusetts General Hospital, Charlestown, Massachusetts; ²Harvard Medical School, Boston, Massachusetts.

 

II3.1
Evaluation of Performances of Organic BioMEMS as Resonators.Georges Dubourg, Isabelle Dufour, Claude Pellet and Cédric Ayela; IMS laboratory, Talence, France.

II3.2
Transferred to II8.10 

II3.3
Transferred to II1.8 

II3.4
Apatite Coating on Porous Silicone for BioMEMS. Luci Cristina O. Vercik, Thiago Antonio V. Menezes, Leticia Baptista and Andres Vercik; Basic Sciences Department - FZEA, Universidade de Sao Paulo, Pirassununga - SP, Brazil.

II3.5 TRANSFERRED TO II2.2 

II3.6
Engineering Hydrid Cunductive Polymer Microelectrode for Improving Biotic/Abiotic Interface.Takeo Miyake^1,2, Yuichi Ido¹, Daisuke Takahashi¹, Syuhei Yoshino¹, Kuniaki Nagamine^1,2 and Matsuhiko Nishizawa^1,2; ¹tohoku.univ, Sendai, Japan; ²CREST, Tokyo, Japan.

II3.7
Complex Modulus Study of PDMS by Dynamic Nanoindentation.Ping Du¹, Chen Cheng², Hongbing Lu² and Xin Zhang¹; ¹Mechanical Engineering, Boston University, Boston, Massachusetts; ²Mechanical Engineering, University of Texas at Dallas, Richardson, Texas.

II3.8
Solvent-Less Planar Lipid Bilayers Formed in Microfabricated Silicon Chips.Azusa Oshima¹, Ayumi Hirano-Iwata^1,2, Tomohiro Nasu¹, Yasuo Kimura¹ and Michio Niwano¹; ¹Tohoku University, Sendai, Japan; ²Japan Science and Technology Agency (JST), Saitama, Japan.

II3.9
Abstract Withdrawn 

II3.10
Functional Design of Porous Drug Delivery Systems Based on Laser Assisted Manufactured Nitinol.Igor V. Shishkovsky, Laboratory of Technological lasers, Lebedev Physics Institute of Russian Academy of Sciences, Samara branch, Samara, Russian Federation.

II3.11
Study of Double Emulsion Behavior by Optical Force.Kyungheon Lee, Sang Bok Kim, Kang Soo Lee, Seung Hwan Kim, Sang Youl Yoon and Hyung Jin Sung; Mechanical Engineering, KAIST, Daejeon, Korea, Republic of.

II3.12
Planar Impedance Sensing Device for Cellular Response Studies.Jinwang Tan and Xin Zhang; boston university, Boston, Massachusetts.

II3.13
Nanostructured Selenium for Preventing Biofilm Formation on Medical Devices. Thomas Webster² and Qi Wang¹; ¹Department of Chemistry, Brown University, Providence, Rhode Island; ²School of Engineering, Brown University, Providence, Rhode Island.

II3.14
Facile Technique for Cell Patterning and Multiple Cell Types Co-Culturing.Alexander Efremov^1,2, Eliana Stanganello¹, Steffen Scholpp¹ and Pavel Levkin^1,2; ¹Department of Toxicology, Karlsruhe Institute of Technology, Karlsruhe, Baden-Württemberg, Germany; ²Department of Applied Physical Chemistry, University of Heidelberg, Heidelberg, Baden-Württemberg, Germany.

II3.15
DNA as a One-Dimensional Chiral Material: Application to B-Z Transition. Hiroshi Kuratsuji and Teruaki Okushima; Research organization of science and engineering of science, Ritsumeikan University, Kusatsu city, Japan.

II3.16
TRANSFERRED TO II1.2 

II3.17
Metal Assisted Plasma Etching (MAPE).Teena James and David H. Gracias; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland.

II3.18
Development of a Microscale Uni-Axial Loading Device for Intercellular Mechanotransduction Study.Qian Wang and Yi Zhao; Biomedical Engineering Department, Ohio State University, Columbus, Ohio.

II3.19
Adhesion and Cohesion in Structures Containing Suspended Microscopic Polymeric Films.Wanliang Shan^1,2,3, Jing Du^1,2, Emily Hampp^1,2, Hannah Li³, George Papandreou³, Cynthia Maryanoff³ and Wole Soboyejo^1,2; ¹Mechanical and Aerospace Engineering, Princeton University, Princeton, New Jersey; ²Princeton Institute for the Science and Technology of Materials, Princeton, New Jersey; ³Cordis Corporation, a Johnson and Johnson Compay, Spring House, Pennsylvania.

II3.20
Visualization of NIR Propagation in Quasi-Zero Index Photonic Crystals Using Upconverting Nanoparticles.Jingyu Zhang, Daniel Gargas, Teresa Pick, Scott Dhuey, Emory Chan, Alexis Ostrowski, Brett Helms, James Schuck, Deirdre Olynick and Stefano Cabrini; Lawrence Berkeley National Lab, Berkeley, California.

 

8:30 AM *II4.1
Computer Assisted Designing and Biofabrication of 3D Hydrogel Structures towards Thick 3D Tissue Engineering.Makoto Nakamura¹, Ken-ichi Arai¹, Hideki Toda¹, Shintaroh Iwanaga¹, Kozo Ito¹, Genci Capi¹ and Toshio Nikaido²; ¹Graduate school of Science and Engineering for research, University of Toyama, Toyama, Toyama, Japan; ²Graduate school of medicine and pharmaceutical science for research, university of toyama, toyama, Japan.

9:00 AM II4.2
Microfluidic Production of Micro-Assemblies with Multiple Geometries and Functionalities.Kunqiang Jiang¹, Don L. DeVoe² and Srinivasa R. Raghavan^3,1; ¹Department of Chemistry and Biochemistry, University of Maryland-College Park, College Park, Maryland; ²Department of Mechanical Engineering, University of Maryland, College Park, Maryland; ³Department of Chemical and Biomolecular Engineering, University of Maryland, College Park, Maryland.

9:15 AM II4.3
BioMEMS for Growth of Endothelial Cells.Susmi Das^1,2,3, Fatima Merchant³ and Wanda Zagozdzon-Wosik¹; ¹Electrical and Computer Eng., University of Houston, Houston, Texas; ²Texas Center for Superconductivity, University of Houston, Houston, Texas; ³College of Technology, University of Houston, Houston, Texas.

9:30 AM *II4.4
Chemical Engineering-Based Multiscale Optimization of 3D Cellular Organization and Oxygen Supply In Vitro.Yasuyuki Sakai, Institute of Industrial Science, University of Tokyo, Tokyo, Tokyo, Japan.

10:00 AM BREAK

10:30 AM *II4.5
Fabrication of Complex Hydrogel Materials by Utilizing Microfluidics and Micromolding. Masumi Yamada, Yoji Naganuma, Emi Yamada, Shunta Kakegawa, Sari Sugaya and Minoru Seki; Applied Chem. & Biotechnol., Grad. Sch. of Eng., Chiba University, Chiba, -, Japan.

11:00 AM *II4.6
3D Cell Co-Culture System on Hydrogel Micro-Patterned Surface.Keitaro Yoshimoto, The University of Tokyo, Tokyo, Japan.

11:30 AM II4.7
Electrohydrodynamic Jet Printing for Hydrogel Cell Culture Substrates.Michael Poellmann¹, Kira L. Barton² and Amy J. Wagoner Johnson³; ¹Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois; ²Mechanical Engineering, University of Michigan, Ann Arbor, Michigan; ³Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois.

11:45 AM II4.8
Toward a Lithographically Patterned Bio-Artificial Pancreas. Jaehyun Park, Yevgeniy V. Kalinin, Christina L. Randall and David H. Gracias; Johns Hopkins University, Baltimore, Maryland.

 

1:30 PM *II5.1
Implementation of BioMEMS for Determining Mechanical Properties of Biological Cells.Svetlana Tatic-Lucic and Markus Gnerlich; ECE, Lehigh University, Bethlehem, Pennsylvania.

2:00 PM II5.2
The Use of Controlled Surface Topography and Flow-Induced Shear Stress to Influence Renal Epithelial Cell Function.Else Frohlich^1,2, Xin Zhang² and Joseph Charest¹; ¹Bioengineering, Draper Laboratory, Cambridge, Massachusetts; ²Mechanical Engineering, Boston University, Boston, Massachusetts.

2:15 PM II5.3
Fabrication and Characterization of a Polymeric Microdevice for Cell Loading with Controllable Strain Distribution.Qian Wang and Yi Zhao; Biomedical Engineering Department, Ohio State University, Columbus, Ohio.

2:30 PM *II5.4
Opto-Mechanical Platforms for Cell Force Study.Xin Zhang, Mechanical Engineering, Boston University, Boston, Massachusetts.

3:00 PM BREAK

3:30 PM *II5.5
Microtechnologies for Studying Cell Mechanobiology.Craig A. Simmons, Department of Mechanical & Industrial Engineering, University of Toronto, Toronto, Ontario, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.

4:00 PM *II5.6
Wetting Phenomena of Phospholipid Films for Electroporating Membranes.Evelyn N. Wang, H. Jeremy Cho and Shalabh C. Maroo; Mechanical Engineering, MIT, Cambridge, Massachusetts.

4:30 PM II5.7
On-Chip Measurements of Cell Compressibility Using Acoustic Standing Wave.Deny Hartono¹, Yang Liu², Kian-Meng Lim^2,3 and Lin-Yue Lanry Yung¹; ¹Department of Chemical and Biomolecular Engineering, National University of Singapore, Singapore, Singapore; ²Singapore-MIT Alliance, National University of Singapore, Singapore, Singapore; ³Department of Mechanical Engineering, National University of Singapore, Singapore, Singapore.

4:45 PM II5.8
Using Dielectric Spectroscopy as a Tool for Mitochondrial Membrane Potential Studies.Divya Padmaraj^1,2, Rohit Pande^1,2, Jarek Wosik^1,2, John H. Miller^2,3 and Wanda Zagozdzon-Wosik¹; ¹Electrical and Computer Engineering, University of Houston, Houston, Texas; ²Texas Center for Superconductivity, University of Houston, Houston, Texas; ³Physics Department, University of Houston, Houston, Texas.

 

8:30 AM *II6.1
Development of Microfluidic Biochip Applied to Cell-Based Assay for Drug Discovery.Toshiyuki Kanamori, Shinji Sugiura, Koji Hattori and Kimio Sumaru; Research Center for Stem Cell Engineering, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.

9:00 AM II6.2
Hydrogel-Filled Silicon Stamps for Generating Multiplexed Protein Microarrays.Erhan Bat, Pascal Jonkheijm and Jurriaan Huskens; Molecular Nanofabrication, University of Twente, Enschede, Overijssel, Netherlands.

9:15 AM *II6.3
2-D and 3-D Cell Microarrays-Based Functional Screening.Xavier Gidrol¹, Eric Sulpice¹, Patricia Obeid¹, Stephanie Combe¹, Frederique Kermarrec¹, Lamya Ghemin¹, Stephanie Porte¹, Amandine Pitaval¹, Manuel Thery² and Nathalie Picollet-D'hahan¹; ¹Laboratoire Biomics, CEA, Grenoble, France; ²Laboratoire de Physiologie Cellulaire et Vegetale, CEA/CNRS/UJF/INRA, Grenoble Cedex 09, France.

9:45 AM II6.4
Microfabricated Polyester Microwell Device for Stem Cell Culture Experiments.Seila Selimovic^1,2, Francesco Piraino^1,2,3, Hojae Bae^1,2, Marco Rasponi³, Alberto Redaelli³ and Ali Khademhosseini^1,2,4; ¹Medicine, Brigham & Women's Hospital, Cambridge, Massachusetts; ²Harvard-MIT Division of Health Sciences and Technology, MIT, Cambridge, Massachusetts; ³Bioengineering, Politecnico di Milano, Milan, Italy; ⁴Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, Massachusetts.

10:00 AM BREAK

10:30 AM *II6.5
Towards Next-Generation Proteomic Assays: Functional Materials as Sieving Matrices and Binding Scaffolds.Amy E. Herr, Dohyun Kim, Mei He, Samuel Tia, Alex Hughes and Chenlu Hou; Bioengineering, UC Berkeley, Berkeley, California.

11:00 AM II6.6
Biohybrid Thin Films for Cardiac Valve Safety Pharmacology Assays.Kartik Balachandran, Matthew A. Hemphill, Leila F. Deravi and Kevin K. Parker; Disease Biophysics Group, Wyss Institute for Biologically Inspired Engineering, School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts.

11:15 AM II6.7
High Throughput Magnetic Cytometry in Native Biological Samples.David Issadore, Jaehoon Chung, Huilin Shao, Ralph Weissleder and Hakho Lee; Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts.

11:30 AM II6.8
Plasmonic Interferometers for High-Throughput, Real-Time, Optical Detection of Biochemical Analytes.Jing Feng, Vince Siu, Alec Roelke, Vihang Mehta, Steve Rhieu, Tayhas G. Palmore and Domenico Pacifici; school of engineering, brown university, Providence, Rhode Island.

11:45 AM II6.9
Thermoset Polyester Droplet-Based Microfluidic Devices for High Frequency Generation.Jin-Young Kim¹, Andrew J. deMello², Soo-Ik Chang³, Jongin Hong⁴ and Danny O'Hare¹; ¹Bioengineering, Imperial College London, London, United Kingdom; ²Chemistry, Imperial College London, London, United Kingdom; ³Biochemistry, Chung-buk National University, Cheongju, Korea, Republic of; ⁴Chemistry, Chung-ang University, Seoul, Korea, Republic of.

 

1:30 PM *II7.1
Wireless Feedback-Controlled Drug Delivery Pumps for Small Animal Research.Ellis Meng, Roya Sheybani, Heidi Gensler and Christian Gutierrez; Biomedical Engineering, University of Southern California, Los Angeles, California.

2:00 PM II7.2
Conductive Polymers for Localized Controlled Release of Therapeutic Agents for Treatment of Open Wounds.Joseph K. Mbugua, Eve Fabrizio, Mark Chase, Theo Nicholson III, June H. Jung, Jeffrey Maskrod, Sigiang Zhu and Ramil Mercado; Crosslink, Springfield, Missouri.

2:15 PM II7.3
A Microfluidic Dialysis Cell for the Characterization of Interactions in Soft Biomaterials.Jan Scrimgeour^1,2, Jae Kyu Cho³, Victor Breedveld³ and Jennifer E. Curtis^1,2; ¹School of Physics, Georgia Institute of Technology, Atlanta, Georgia; ²Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia; ³School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia.

2:30 PM II7.4
Nanoporous Gold: A Biomaterial for Microfabricated Drug-Delivery Platforms.Erkin Seker^1,2, Yevgeny Berdichevsky³, Kevin Staley³ and Martin Yarmush^1,2; ¹Center for Engineering in Medicine, Harvard Medical School & Massachusetts General Hospital, Boston, Massachusetts; ²Shriners Hospitals for Children, Boston, Massachusetts; ³Neurology, Harvard Medical School & Massachusetts General Hospital, Boston, Massachusetts.

2:45 PM II7.5
Assembly of Bio-Photonic Materials Using Proteins Isolated from Cuttlefish Sepia Officinalis.Leila Deravi¹, George Bell², Andrew Magyar³, Holly McIlwee¹, Lydia Mathger², Alan Kuzirian², Evelyn Hu³, Roger Hanlon² and Kevin K. Parker¹; ¹Disease Biophysics Group, Wyss Institute for Biologically Inspired Engineering, School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts; ²Marine Biological Labs, Woods Hole, Massachusetts; ³School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts.

3:00 PM BREAK

3:30 PM *II7.6
Applications of Sensing and Actuation Materials in Medical Micro-Instruments.Yogesh Gianchandani, EECS Department, University of Michigan, Ann Arbor, Michigan.

4:00 PM II7.7
Nanofluidic/Plasmonic Biosensors for Point of Care Virus Diagnostics and Detection of Biomarkers with the Naked Eye.Ahmet A. Yanik^1,2,5, Min Huang^1,2, Arif Cetin^1,2, Alp Artar^1,2, Hossein Mousavi⁴, Alexander Khanikaev⁴, Gennady Shvets⁴, John Connor^3,2 and Hatice Altug^1,2; ¹Electrical and Computer Engineering, Boston Univ, Boston, Massachusetts; ²Photonics Center, Boston University, Boston, Massachusetts; ³Microbiology, Boston University Medical School, Boston, Massachusetts; ⁴Physics, University of Texas, Austin, Boston, Massachusetts; ⁵Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

4:15 PM II7.8
Antimicrobial Peptide Functionalized Graphene Nanosensors for Highly Sensitive Pathogen Detection.Manu Sebastian Mannoor, Jefferson Clayton and Michael McAlpine; Mechanical & Aerospace Engineering, Princeton University, Princeton, New Jersey.

4:30 PM II7.9
Supersonic Cluster Beam Implantation: A Novel Approach for Producing Compliant and Biocompatible Micro-Circuits on Elastomers.Gabriele Corbelli^1,2, Cristian Ghisleri^1,2, Paolo Milani^1,2 and Luca Ravagnan²; ¹CIMAINA & Physics Department, Università degli Studi di Milano, Milano, Italy; ²WISE s.r.l., Milano, Italy.

4:45 PM II7.10
AL2O3 Gate Dielectric with Ion Impermeability for In Vivo Biocircuitry.Anisha Ramesh¹, Fang Ren¹, Patricia Casal², Andy Theiss², Samit Gupta², Stephen C. Lee² and Paul R. Berger^1,3; ¹Electrical and Computer Engineering, The Ohio State University, Columbus, Ohio; ²Department of Biomedical Engineering, The Ohio State University, Columbus, Ohio; ³Department of Physics, The Ohio State University, Columbus, Ohio.

 

8:30 AM *II8.1
Microfluidic Production of Cell Spheroid and Functional Fibers for Bottom-up Engineering of Tissue.SangHoon Lee, Biomedical Engineering, Korea University, Seoul, Korea, Republic of.

9:00 AM II8.2
Conformal Deposition of Poly(N-isopropylacrylamide) on Elastomeric Microstructures.Halil Tekin^1,2,3, Tonia Tsinman^2,4, Gozde Ozaydin-Ince⁵, Karen K. Gleason⁵, Melik C. Demirel⁶, Robert Langer*^3,5,7 and Ali Khademhosseini*^2,7,8; ¹Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts; ²Department of Medicine, Center for Biomedical Engineering, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts; ³David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts; ⁴Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts; ⁵Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts; ⁶Materials Research Institute and Department of Engineering Science, Pennsylvania State University, University Park, Pennsylvania; ⁷Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts; ⁸Wyss Institute for Biologically Inspired Engineering, Harvard Medical School, Boston, Massachusetts.

9:15 AM II8.3
Surface Engineering for Rapid Cell Detachment by Using Electrochemical Desorption of a Zwitterionic Oligopeptide Layer.Takahiro Kakegawa, Hiroaki Suzuki and Junji Fukuda; University of Tsukuba, Tsukuba, Ibaraki, Japan.

9:30 AM *II8.4
Cell and Tissue Culture in Structured Microenvironment.Teruo Fujii, Institute of Industrial Science, University of Tokyo, Tokyo, Japan; JST CREST, Tokyo, Japan.

10:00 AM BREAK
 

10:30 AM II8.5
All-Elastomeric, Multiplexed Microfluidic Phage Display Biopanning.Kellye Cung¹, Michael C. McAlpine¹, Russell L. Slater¹, Yue Cui¹ and Habib Ahmad²; ¹Princeton University, Princeton, New Jersey; ²California Institute of Technology, Pasadena, California.

10:45 AM II8.6
Voltage Controlled Electrostatic Trap for Confining Nanometric Objects in a Fluid.Ashwin Panday^1,2, Brandon Lucas³ and L. Jay Guo^1,2,3; ¹Macromolecular Science and Engineering, University of Michigan, Ann Arbor, Michigan; ²Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, Michigan; ³Applied Physics, University of Michigan, Ann Arbor, Michigan.

11:00 AM II8.7
Smart Surfaces: Use of Electrokinetics for Selective Modulation of Biomolecular Affinities.Sam Emaminejad^1,2, Mehdi Javanmard², Robert W. Dutton¹ and Ronald W. Davis²; ¹Electrical Engineering, Stanford University, Stanford, California; ²Biochemistry, Stanford Genome Technology Center, Stanford, California.

11:15 AM II8.8
Raman Mapping of Surface Distribution and Trace Detection of Common Biomolecules and Stress-Related Biomarkers.Zachary A. Combs, Sehoon Chang, Kyle D. Anderson, Richard Davis and Vladimir V. Tsukruk; Materials Science and Engineering, Georgia Institute of Technology, Atlanta, Georgia.

11:30 AM II8.9
Combinatorial Identification and Zygosity Discrimination of Apolipoprotein-E Single Nucleotide Polymorphisms in a Microfluidic Electrochemical Device.Allen H. Yang, Kuangwen Hsieh and Tom Soh; University of California at Santa Barbara, Santa Barbara, California.

11:45 AM II8.10Stable and Solvent-Less Lipid Bilayers Based on Nano- and Micro-Fabrication.Ayumi Hirano-Iwata^1,2, Azusa Oshima¹, Tomohito Nasu¹, Yasuo Kimura¹ and Michio Niwano¹; ¹Tohoku University, Sendai, Japan; ²PRESTO, Japan Science and Technology Agency (JST), Saitama, Japan.


 

1:30 PM *II9.1
Laser Treated Paper: A Versatile Microsystem Substrate. Girish Chitnis^1,3 and Babak Ziaie^2,3,4; ¹School of Mechanical Engineering, Purdue University, West Lafayette, Indiana; ²School of Electrical and Computer Engineering, Purdue University, West Lafayette, Indiana; ³Birck Nanotechnology Center, Purdue University, West Lafayette, Indiana; ⁴Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana.

2:00 PM II9.2
Anisotropic Cellular Alignment on Nano-Wrinkled Polymeric Surface.Toshinori Fujie^1,2, Francesco Greco¹, Silvia Taccola^1,3, Leonardo Ricotti³, Arianna Menciassi^1,3 and Virgilio Mattoli¹; ¹Center for MicroBioRobotics IIT@SSSA, Istituto Italiano di Tecnologia, Pontedera, Pisa, Italy; ²European Biomedical Science Institute (EBSI), Organization for European Studies, Waseda University, Tokyo, Japan; ³Biorobotics Institute, Scuola Superiore Sant’Anna, Polo Sant’Anna Valdera, Pontedera, Pisa, Italy.

2:15 PM II9.3
A Rapid and Sensitive Detection of Cardiac Markers in Human Serum Using Surface Acoustic Wave Immunosensor.Joonhyung Lee, Yoon Suk Choi, Yeol Ho Lee, Jung Nam Lee, Hun Joo Lee, Sang Kyu Kim, Kyung Yeon Han, Soo Suk Lee and Jae Chan Park; BioLab/Samsung Advanced Institute of Technology, Samsung Electronics, Yongin-si, Gyeonggi-do, Korea, Republic of.

2:30 PM II9.4
Efficient Capture and Detection of HIV Subtypes by Oriented Antibody Immobilization in a Microchip for Enhanced HIV Viral Load Detection Applications.Shuqi Wang¹, Matin Esfahani¹, Umut A. Gurkan¹, Giguelc F. Francoise³, Daniel R. Kuritzkes² and Utkan Demirci¹; ¹Harvard-MIT Health Sciences and Technology, Harvard-MIT Health Sciences and Technology, Cambridge, Massachusetts; ²Harvard Medical School, Harvard University, Cambridge, Massachusetts; ³Infectious Diseases Unit, Massachusetts General Hospital, Boston, Massachusetts.

2:45 PM II9.5
Enhanced Biosensing Using Delay Path Modifications in Shear Horizontal Surface Acoustic Wave Sensors.Subramanian Sankaranarayanan¹, Stefan Cular², Reetu Singh² and Venkat Bhethanabotla²; ¹Center for Nanoscale Materials, Argonne National Lab, Argonne, Illinois; ²Chemical and Biomedical engineering, USF, Tampa, Florida.

3:00 PM BREAK

3:30 PM *II9.6
Microfabricated Electrochemical Devices for the Determination of Compounds Related to Cell Metabolism.Hiroaki Suzuki, Graduate School of Pure and Applied Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.

4:00 PM II9.7
Template-Stripped Plasmonic Nanohole Arrays for Surface Plasmon Resonance Biosensing.Hyungsoon Im¹, Si-Hoon Lee², Nathan J. Wittenberg¹, Timothy W. Johnson¹, Nathan C. Lindquist¹, Prashant Nagpal³, David J. Norris⁴ and Sang-Hyun Oh^1,2; ¹Electrical and Computer Engineering, University of Minnesota, Minneapolis, Minnesota; ²Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota; ³Los Alamos National Laboratory, Los Alamos, New Mexico; ⁴ETH Zürich, Zürich, Switzerland.

4:15 PM II9.8
Miniature Magnetic Resonance System for Point-of-Care Diagnostics.Changwook Min¹, David Issadore¹, Jaehoon Chung¹, Huilin Shao¹, Monty Liong¹, Ralph Weissleder^1,2 and Hakho Lee¹; ¹Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts; ²Department of Systems Biology, Harvard Medical School, Boston, Massachusetts.

4:30 PM II9.9
Design, Fabrication, and Characterization of Nanogap Capacitive Sensors for Ultrasensitive Biosensing Applications. Oguz Hanoglu¹, Handan Acar², Selim Sulek², Firat Yilmaz¹, Mustafa Yuksel⁴, Sedat Agan³, Necmi Biyikli², Mustafa O. Guler² and Ali K. Okyay^1,2; ¹Electrical and Electronics Engineering, Bilkent University, Ankara, Turkey; ²UNAM - Institute of Materials Science and Nanotechnology, Bilkent University, Ankara, Turkey; ³Physics, Kirikkale University, Kirikkale, Turkey; ⁴Ankara Vocational School of Health Sciences, Fatih University, Ankara, Turkey.

4:45 PM II9.10
Electrical Detection of Surface Enzymatic Reaction in Nanochannels.Chuanhua Duan¹, Yu-Feng Chen², Dong-Kwon Kim³, Christopher M. Brown⁴, Charles S. Craik⁴ and Arun Majumdar^1,5; ¹Mechanical Engineering, University of California, Berkeley, Berkeley, California; ²Green Energy and Environment Research Laboratories, Industrial Technology Research Institute, Hsinchu, Taiwan; ³Mechanical Engineering, Ajou University, Suwon, Korea, Republic of; ⁴Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California; ⁵ARPA-E, US Department of Energy, Washington, District of Columbia.