Symposium JJ: Nanofunctional Materials, Nanostructures, and Nanodevices for Cancer Applications
-
- November 28 - December 2, 2011
- Hynes Convention Center, Boston, MA
-
Meeting Chairs:
Cammy R. Abernathy, Paul V. Braun, Masashi Kawasaki, Kathryn J. Wahl
SYMPOSIUM JJ
JJ: Nanofunctional Materials, Nanostructures, and Nanodevices for Cancer Applications
November 28 - 30, 2011
Chairs
| Piotr Grodzinski |
|
National Cancer Institute |
| Scott Manalis |
|
Massachusetts Institute of Technology |
| Sonke Svenson |
|
Cerulean Pharma Inc. |
| Xing-Jie Liang |
|
National Center for Nanoscience and Technology of China |
| Wenbin Lin |
|
University of North Carolina-Chapel Hill |
* Invited paper
SESSION JJ1: Detection of Biomarkers and Biological Response
Chair: Piotr Grodzinski
Monday Morning, November 28, 2011
Room 203 (Hynes)
9:00 AM *JJ1.1
Nanotheranostics for Cancer: Targeted Nanoparticles for Tumor Imaging, Image-Guided Drug Delivery and Light Induced Therapy.Paras N. Prasad1,2 and Tymish Y. Ohulchanskyy1; 1Institute for Lasers, Photonics and Biophotonics, State University of New York at Buffalo, Buffalo, New York; 2Chemistry, State University of New York at Buffalo, Buffalo, New York.
9:30 AM JJ1.2
Novel Multifunctional Nanocarriers Capable of In Vivo Rapidly Controlled Drug Release for MR Imaging and Targeted Epilepsy Therapy.Hsin-Yang Haung, Department of Materials Sciences and Engineering, National Chiao Tung University, Hsin Chu, TAIWAN, Taiwan.
9:45 AM JJ1.3
``AND'' Logic T1-T2 Nanoparticles for Fault-Free MR Imaging.Jin-sil Choi1, Tae-hyun Shin1, Dongwon Yoo1, Ho-Taek Song2, Eung Yeop Kim2 and Jinwoo Cheon1; 1Dept. of Chemistry, Yonsei University, Seoul, Korea, Republic of; 2Department of Radiology, College of Medicine, Yonsei University, Seoul, Korea, Republic of.
10:00 AM JJ1.4
Quantum-Dot-Decorated Enzyme Nanocapsules for Cancer Imaging and Therapeutics.Juanjuan Du, Ming Yan, Titiana Segura, Yi Tang and Yunfeng Lu; Department of Chemical and Biomolecular Engineering, UCLA, Los Angeles, California.
10:15 AM BREAK
10:30 AM *JJ1.5
Magnetic Nanoparticles for Theranostics and Cell Actuations.Jinwoo Cheon, Yonsei University, Seoul, Korea, Republic of.
11:00 AM JJ1.6
Magnetic Nanoparticles as MRI Contrast Agents and for Selective Targeting of Cells.Wolfgang Tremel1, Thomas Schladt1, Bahar Nakhjavan1, Kerstin Koll1, Heiko Bauer1, Oskar Koehler1, Isabell Schick1, Anna Schilmann1, Muhammad N. Tahir1, Filipe Natalio1, Peter Bluemler2 and Kerstin Muennemann3; 1Institut für Anorganische Chemie, Johannes Gutenberg-Universität, Mainz, Germany; 2Institut für Physik, Johannes Gutenberg-Universität, Mainz, Germany; 3Max Planck-Institut für Polymerforschung, Mainz, Germany.
11:15AM JJ1.7
Modulating the Luminescence of Upconverting Nanoparticles Using Dithienylethene Photoswitches for Biolabeling Applications.John-Christopher Boyer, Carl-Johan Carling and Neil Branda; Chemistry, Simon Fraser University, Burnaby, British Columbia, Canada.
11:30 AM JJ1.8
Incorporation of Quantum-Dots with Mesoporous Silica Nanoparticles for Intracellular Targeting and In Vivo Images.Po-Jung Chen1, Shang-Hsiu Hu2, San-Yuan Chen3 and Dean-Mo Liu4; 1National Chiao Tung University, Hsinchu, Taiwan; 2National Chiao Tung University, Hsinchu, Taiwan; 3National Chiao Tung University, Hsinchu, Taiwan; 4National Chiao Tung University, Hsinchu, Taiwan.
SESSION JJ2: Imaging and In-vivo Detection Using Nanoparticles
Chair: Scott Manalis
Monday Afternoon, November 28, 2011
Room 203 (Hynes)
1:30 PM *JJ2.1
Multiplex Wash-Free Magneto-Nanosensors for Cancer Diagnostics and Drug Development.Shan X. Wang, Materials Science and Engineering, Stanford University, Stanford, California.
2:00 PM JJ2.2
Quantitative Analysis of Multiple Urinary Biomarkers of Carcinoid Tumors through Gold-Nanoparticle-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry.Tsung-Rong Kuo1,4, Jinn-Shiun Chen2, Yu-Chen Chi1, Chia-Yi Tsai3, Cho-Chun Hu3 and Chia-Chun Chen1,4; 1Chemistry, Natl Taiwan Normal University, Taipei, Taiwan; 2Division of Colorectal Surgery, Chang Gung University, Taoyuan, Taiwan; 3Natural Science Education, National Taitung University, Taitung, Taiwan; 4Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei, Taiwan.
2:15 PM JJ2.3
High-Performance Electrochemical Sensing of Cancerous Protease (Legumain) Using Nanoelectrode Arrays.Lateef Uddin Syed, Luxi Zhang, Allan M. Prior, Jianwei Liu, Duy H. Hua and Jun Li; Chemistry, Kansas State University, Manhattan, Kansas.
2:30 PM JJ2.4
Investigating Receptor-Ligand Interactions on Tunable Nanostructured, Biofunctionalized Surfaces under Flow.Sebastian Kruss1,2, Luise Erpenbeck3, Michael Schoen3 and Joachim Spatz1,2; 1MPI for Intelligent Systems, Stuttgart, Germany; 2Physical Chemistry, Heidelberg University, Heidelberg, Germany; 3Department of Dermatology, Göttingen University, Heidelberg, Germany.
2:45 PM JJ2.5
Exploring the Impact of Cell Mechanics on Cancer Progression with the Microfluidic Optical Stretcher.Mareike Zink1, Franziska Wetzel1, Anatol Fritsch1, Steve Pawlizak1, Tobias Kiessling1, Kenechukwu D. Nnetu1, Lars-Christian Horn2, Michael Hoeckel3 and Josef A. Kaes1; 1Soft Matter Physics Division, University of Leipzig, Leipzig, Germany; 2Institute of Pathology, University of Leipzig, Leipzig, Germany; 3Department of Obstetrics and Gynecology, University of Leipzig, Leipzig, Germany.
3:00 PM BREAK
3:30 PM *JJ2.6
Implanted Diagnostic Devices.Michael J. Cima, Department of Materials Science & Engineering, Massachusetts Inst. of Technology, Cambridge, Massachusetts; The David H. Koch Institute for Integrative Cancer Research, Massachusetts Inst. of Technology, Cambridge, Massachusetts.
4:00 PM JJ2.7
Sensing Energy Metabolism In Vivo - Visualization of Lipolytic Enzyme Activity by Real-Time MRI Using Nanocrystals.Oliver T. Bruns1,2, Alexander Bartelt3, Ulrich Tromsdorf5, Horst Weller5, Moungi Bawendi1, Rudolph Reimer2, Barbara Freund3, Peter Nielsen3, Joerg Heeren3 and Harald Ittrich4; 1Chemistry, MIT, Cambridge, Massachusetts; 2Microtechnology and Electron Microscopy, Heinrich-Pette-Institute, Hamburg, Hamburg, Germany; 3Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Hamburg, Germany; 4Diagnostic and Interventional Radiology Department and Clinic, University Medical Center Hamburg-Eppendorf, Hamburg, Hamburg, Germany; 5Chemistry, University of Hamburg, Hamburg, Hamburg, Germany.
4:15 PM JJ2.8
Development of Efficient Quantum Dot Antibody(QD-Ab) Conjugation to Label Single Cells In Vivo.Hee-Sun Han1, Jayeeta Bhaumik2, Walid S. Kamoun2, Becky Chen2, Dan G. Duda2, Rakesh K. Jain2 and Moungi Bawendi2; 1Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts; 2Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
4:30 PM JJ2.9
Rapid, Label-Free, Electrical Whole Blood Bioassay Based on Nanobiosensor System.Hsiao-Kang Chang and Chongwu Zhou; Electrical Engineering, Univ. of Southern California, Los Angeles, California.
SESSION JJ3: Bio-Nano-Material for Cancer I
Chair: Xing-Jie Liang
Tuesday Morning, November 29, 2011
Room 203 (Hynes)
8:30 AM *JJ3.1
Quantum Dots Capable of Efficient Translocation through Nuclear Pore Complexes.Jan Liphardt, Physics, UC Berkeley, Berkeley, California.
9:00 AM JJ3.2
New Route for the Synthesis of Multifunctional Gold Nanorods - Surgical Technology for Spectroscopy, Imaging and Therapy.Clement Barriere, Pilar B. Garcia-Allende, Ji Qi and Daniel S. Elson; Surgery and Cancer, Imperial College London, London, United Kingdom.
9:15 AM JJ3.3
Selective Triggered Release from Gold Nanorods.Kimberly Hamad-Schifferli, Biological and Mechanical Engineering, MIT, Cambridge, Massachusetts.
9:30 AM JJ3.4
Hydrodynamic Fractionation of Finite Size Gold Nanoparticle Clusters for Biomedical Applications.De-Hao Tsai1, Tae Joon Cho1, Frank W. DelRio1, Julian S. Taurozzi1, Michael R. Zachariah1,2 and Vincent A. Hackley1; 1Materials Measurement Laboratory, National Institute of Standards and Technology, Gaithersburg, Maryland; 2Departments of Mechanical Engineering and Chemistry, University of Maryland, College Park, Maryland.
9:45 AM JJ3.5
Force Spectroscopy Mapping of the Mechanical Properties of Polyethylene Glycol Brushes on Gold Substrates.Gheorghe Stan, Frank W. DelRio, Robert I. MacCuspie and Robert F. Cook; Ceramics Division, National Institute of Standards and Technology, Gaithersburg, Maryland.
10:00 AM BREAK
10:30 AM *JJ3.6
Nanomaterial Characterization: Methodologies for Successful Drug Development.Anil K. Patri, Nanotechnology Characterization Laboratory, SAIC-Frederick, Inc., Frederick, Maryland.
11:00 AM JJ3.7
Acid- and Urea-Functionalized Polycarbonate Micellar Nanoparticles Stabilized by Hydrogen-Bonding for Anticancer Drug Delivery.Amalina B. Attia1, Jeremy Tan1, Chuan Yang1, James L. Hedrick2 and Yi-Yan Yang1; 1Institute of Bioengineering and Nanotechnology, Singapore, Singapore; 2IBM Almaden Research Center, San Jose, California.
11:15 AM JJ3.8
Iron Carbide Nanoparticles Elaboration: Composition, Size Control and Air Stability. Applications to Magnetic Hyperthermia.Anca Meffre, Boubker Mehdaoui, Sebastien Lachaize, Julian Carrey, Pier Fazzini, Marc Respaud and Bruno Chaudret; INSA toulouse, Toulouse, France.
11:30 AM JJ3.9
Impact of Gold Nanoparticle Size and Surface Chemistry on Diffusion in Poly(Ethylene Glycol) Hydrogels.Stephanie L. Hume and Kavita M. Jeerage; Materials Reliability Division, National Institute of Standards and Technology, Boulder, Colorado.
11:45 AM JJ3.10
Gold Nanoparticles with Tuning Near Infrared Absorption via Reaction of HAuCl4 and Na2S2O3 for Low Power Photothermal Cancer Therapy.Guandong Zhang1, Jacek B. Jasinski2, Dhruvinkumar Patel1, Kurtis James1, Xinghua Sun1 and Andre M. Gobin1; 1Bioengineering Department, University of Louisville, Louisville, Kentucky; 2Conn Center for Renewable Energy Research, University of Louisville, Louisville, Kentucky.
SESSION JJ4: Nanotechnology-Enabled Drug Delivery and Therapy
Chair: Sonke Svenson
Tuesday Afternoon, November 29, 2011
Room 203 (Hynes)
1:30 PM *JJ4.1
Improving Delivery and Efficacy of Nano-Therapeutics by Normalizing Tumor Microenvironment.Rakesh K. Jain, Harvard Medical School - Massachusetts General Hospital, Boston, Massachusetts.
2:00 PM JJ4.2
Polymeric Backpacks for Cell-Mediated Drug Delivery.Jonathan Gilbert1, Aaron Anselmo3, Albert Swiston2, Nishit Doshi3, Samir Mitragotri3, Robert Cohen1 and Michael Rubner2; 1Chemical Engineering, MIT, Cambridge, Massachusetts; 2Materials Science and Engineering, MIT, Cambridge, Massachusetts; 3Chemical Engineering, University of California Santa Barbara, Santa Barbara, California.
2:15 PM JJ4.3
Targeted Delivery of Multicomponent Cargos to Cancer via Nanoporous Particle-Supported Lipid Bilayers.Carlee Ashley1, Eric Carnes2, David Padilla2, Katharine Epler2, Robert Castillo2, Cheryl Willman3,5, Bryce Chackerian4,5, David Peabody4,5, Walker Wharton3,5 and Jeffrey Brinker2,5,6; 1Biotechnology and Bioengineering, Sandia National Labs, Livermore, California; 2Chemical Engineering, University of New Mexico, Albuquerque, New Mexico; 3Pathology, University of New Mexico, Albuquerque, New Mexico; 4Molecular Genetics and Microbiology, University of New Mexico, Albuquerque, New Mexico; 5Cancer Center, University of New Mexico, Albuquerque, New Mexico; 6Self-Assembled Materials, Sandia National Labs, Albuquerque, New Mexico.
2:30 PM JJ4.4
Ultrastable, Redispersible, and Small Organically Modified Mesoporous Silica Nanoparticles as Carriers for Anticancer Drug Delivery.Yu-Shen Lin and Christy L. Haynes; Chemistry, University of Minnesota, Minneapolis, Minnesota.
2:45 PM JJ4.5
Precise Manipulation of Gold Nanowires as Delivery Vehicles for Cancer Therapeutics.Ike S. Chi1, Danru Qu2, XingYu Liu1, Chia-Ling Chien2, Hai-Quan Mao1,3 and Robert C. Cammarata1; 1Materials Science and Engineering, Johns Hopkins University, Baltimore, Maryland; 2Physics and Astronomy, Johns Hopkins University, Baltimore, Maryland; 3Whitaker Biomedical Engineering Institute, Johns Hopkins University, Baltimore, Maryland.
3:00 PM BREAK
3:30 PM *JJ4.6
Design of Polymeric Nanoparticles to Improve Distribution Volume to Treat Brain Tumors.W. Mark Saltzman1, Jiangbing Zhou1,2, Toral Patel2 and Joseph Piepmeier2; 1Department of Biomedical Engineering, Yale University, New Haven, Connecticut; 2Department of Neurosurgery, Yale University, New Haven, Connecticut.
4:00 PM JJ4.7
Targeting Acidic Tumors with pH Responsive Luminescent Gold Nanoparticles.Jie Zheng, University of Texas at Dallas, Richardson, Texas.
4:15 PM JJ4.8
Dexamethasone-Releasing Nanoparticles Assembled from Amphiphilic Block Copolyesters Bearing Pendant Cyclic Ketals.Xinqiao Jia, Materials Science and Engineering, University of Delaware, Newark, Delaware.
4:30 PM JJ4.9
Functional Nanoparticles for the Manipulation of Angiogenesis: Towards a New Method for Cancer Treatment.Antonios Kanaras1, Dorota Bartczak1, Otto L. Muskens1, Tim Sanchez-Elsner2 and Timothy M. Millar2; 1School of Physics and Astronomy, University of Southampton, Southampton, United Kingdom; 2School of Medicine, University of Southampton, Southampton, United Kingdom.
4:45 PM JJ4.10
Biosynthesis and Adhesion of Gold Nanoparticles for Breast Cancer Detection and Treatment.Emily L. Hampp1,2, Richard Botah3, Shola Odusanya4, Nicolas Anuku5, Karen Malatesta1 and Winston O. Soboyejo1,2; 1Mechanical & Aerospace Engineering, Princeton University, Princeton, New Jersey; 2Princeton Institute for Science and Technology of Materials (PRISM), Princeton University, Princeton, New Jersey; 3Department of Materials Science and Engineering, African University of Science and Technology, Abuja, Nigeria; 4Biotechnology Advanced Laboratory, Sheda Science and Technology Complex, Abuja, Nigeria; 5Chemistry and Chemical Technology, Bronx Community College, New York, New York.
SESSION JJ5: Poster Session - Nanofunctional Materials, Nanostructures, and Nanodevices for Cancer Applications
Chairs: Piotr Grodzinski and Wenbin Lin
Tuesday Evening, November 29, 2011
8:00 PM
Exhibition Hall D (Hynes)
JJ5.1
Abstract Withdrawn
JJ5.2
Abstract Withdrawn
JJ5.3
Design and Application of Modified Gold Nanoparticles in Cancer Diagnosis and Therapy. Ieda M. Paino, Valeria Marangoni and Valtencir Zucolotto; Nanomedicine and Nanotoxicology Laboratory, Physics Institute of São Carlos - Universidade de Sao Paulo, São Carlos, São Paulo, Brazil.
JJ5.4
Synthesis and Characterization of Magnetite Nanoparticles Modified with PEG-Based Amphiphilic Copolymers.Ryo Kasuya1, Teppei Kikuchi2 and Jeyadevan Balachandran3; 1National Institute of Advanced Industrial Science and Technology, Nagoya, Japan; 2Graduate School of Environmental Studies, Tohoku University, Sendai, Japan; 3School of Engineering, University of Shiga Prefecture, Hikone, Japan.
JJ5.5
ABSTRACT WITHDRAWN
JJ5.6
Potential of Polyion Complex Nanoparticle Composed of Mercaptoundecahydrododecaborane-Appended High Molecular Weight Polyamine as a Boron Carrier for Neutron Capture Therapy.Takeshi Nagasaki1, Masayuki Umano1, Hironobu Yanagie2, Mitsunori Kirihata3, Shin-ichiro Masunaga4 and Koji Ono4; 1Department of Applied Chemistry and Bioengineering, Osaka City University, Osaka, Osaka, Japan; 2Department of Nuclear Engineering and Management, The University of Tokyo, Tokyo, Tokyo, Japan; 3Department of Bioscience and Informatics, Osaka Prefecture University, Sakai, Osaka, Japan; 4Reserch Reactor Institute, Kyoto University, Kumatori, Osaka, Japan.
JJ5.7
Superparamagnetic Iron Oxide Nanoparticles in Tumor Diagnostics.Aruna Sigdel1, Lan Yao2, Yana K. Reshetnyak2 and Shouheng Sun1; 1Chemistry, Brown University, Providence, Rhode Island; 2Physics, University of Rhode Island, Kingston, Rhode Island.
JJ5.8
Gold Nanoparticle Tags for SERS-Based Imaging of Human Glioblastoma Cells.Laura Fabris1, Prabhas V. Moghe2, Bryan J. Paladini1 and Dominik J. Naczynski2; 1Materials Science and Engineering, Rutgers University, Piscataway, New Jersey; 2BIomedical Engineering, Rutgers University, Piscataway, New Jersey.
JJ5.9
Abstract Withdrawn
JJ5.10
Selective Triggered Release from Gold Nanorods.Helena de Puig1,4, Salmaan H. Baxamusa2, Stefania Federici5, Helen D'Couto2, Dorma Flemister2, Mercedes Balcells3,4, Paolo Bergese5 and Kimberly Hamad-Schifferli1,2; 1Mechanical Engineering, MIT, Cambridge, Massachusetts; 2Biological Engineering, MIT, Cambridge, Massachusetts; 3Health Sciences and Technology, MIT, Cambridge, Massachusetts; 4Institut Químic de Sarrià, Universitat Ramon Llull, Barcelona, Spain; 5Chemistry for Technologies Laboratory and INSTM, University of Brescia, Brescia, Italy.
JJ5.11
Abstract Withdrawn
JJ5.12
Functionalized Platinum Nanoparticles as an Active Targeting Drug for Cancer in Zebrafish.Yiwei Teow1,2, Zhiyuan Gong2,3 and Suresh Valiyaveettil1,2; 1Chemistry, National University of Singapore, Singapore, Singapore; 2NUS Graduate School for Integrative Sciences and Engineering (NGS), Singapore, Singapore; 3Biological Sciences, National University of Singapore, Singapore, Singapore.
JJ5.13
Abstract Withdrawn
JJ5.14
Measuring the Efficacy of Ligand Displacement on Functionalized Gold Nanaoparticles Using Complementary Characterizations - Applications in Cancer Therapeutics.De-Hao Tsai1, Melanie P. Shelton1, Frank W. DelRio1, Suvajyoti Guha1,2, Michael R. Zachariah1,2 and Vincent A. Hackley1; 1Materials Measurement Laboratory, National Institute of Standards and Technology, Gaithersburg, Maryland; 2Departments of Mechanical Engineering and Chemistry, University of Maryland, College Park, Maryland.
JJ5.15
Surface Modification of Titanium Dioxide to Enhance Biocompatibility and Selectivity for Use in Photodynamic Cancer Therapy.Isabella J. Schmitt and Matthew A. Tarr; Department of Chemistry and Advanced Materials Research Institute, University of New Orleans, New Orleans, Louisiana.
JJ5.16
Human Serum Albumin Nanoparticles Loaded with Magnetic Nanoparticles and Organic Molecules for Use in Cancer Treatment.Isabella J. Schmitt1, Kristen E. Schexnayder1, David K. Bwambok1, Arden Wells2, Leszek Malkinski2 and Matthew A. Tarr1; 1Department of Chemistry and Advanced Materials Research Institute, University of New Orleans, New Orleans, Louisiana; 2Department of Physics and Advanced Materials Research Institute, University of New Orleans, New Orleans, Louisiana.
JJ5.17
Synthesis of Gold Nanoparticles Coated with pH-Responsive Polymers and Evaluation of the Cellular Uptake.Takeo Ito, Eriko Kusaka, Yu Isobe and Sei-ichi Nishimoto; Kyoto University, Kyoto, Japan.
JJ5.18
Zwitterionic-Coated Tantalum Oxide: New Nanoparticle Contrast Agents for X-Ray/CT Medical Imaging.Matthew Butts, Peter Bonitatibus, Robert Colborn, Todd Luttrell, David Gascoyne, Andrew Torres, Brian Lee, Paul Fitzgerald and Michael Marino; Molecular Diagnostics Platform, GE Global Research, Niskayuna, New York.
JJ5.19
Polyelectrolyte Multilayer Films Using Chemically Modified Hyaluronic Acid and Poly(L-lysine) or Chitosan to Deliver the Hydrophobic Drug Paclitaxel. Prathamesh Kharkar1, Thomas Boudou1, Jing Jing2, Di Cui2, Rachel Auzely-Velty2 and Catherine Picart1; 1Department of Bioengineering, Grenoble Institute of Technology, Grenoble, France; 2CNRS, CERMAV, Grenoble, France.
JJ5.20
Demonstration of Biocompatibility of Single Walled Carbon Nanotubes with Blood Leukocytes.Krishna Kiran Medepalli1, Bruce W. Alphenaar1, Ashok Raj2 and Palaniappan Sethu3; 1Department of Electrical and Computer Engineering, Speed School of Engineering, University of Louisville, Louisville, Kentucky; 2Division of Pediatrics, School of Medicine, University of Louisville, Louisville, Kentucky; 3Department of Bioengineering, Speed School of Engineering, University of Louisville, Louisville, Kentucky.
JJ5.21
The In Vitro Anticancer Activity of Nitrosyl Complexes Loaded in Biopolymer Nanoparticles.Anderson J. Gomes1, Enilza M. Espreafico3 and Elia Tfouni2; 1Faculdade de Ceilandia, University of Brasilia FCE-UnB, Brasília, Brazil; 2Chemistry, Faculdade de Filosofia Ciencias e Letras de Ribeirao Preto-FFCLRP-USP, Ribeirao Preto, Brazil; 3Biologia Celular e Molecular e Bioagentes Patogênicos, Faculdade de Medicina de Ribeirao Preto-FMRP-USP, Ribeirao Preto, Brazil.
JJ5.22
Shell Cross-Linked Albumin Nanocapsules for Enhanced Intracellular Delivery of Paclitaxel.Jeong Yu Lee1, Ki Hyun Bae1, Jee Seon Kim1, Yoon Sung Nam1,2 and Tae Gwan Park1; 1Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Korea, Republic of; 2Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea, Republic of.
JJ5.23
Abstract Withdrawn
JJ5.24
Biocompatible Quantum Dot Conjugates and In Vivo Multiplexed near-Infrared Imaging System.Nayoun Won1, Suk Ho Bhang2, Sanghwa Jeong1, Kangwook Kim1, Ho Jin1, Jutaek Nam1, Jungheon Kwag3, Joonhyuck Park3, Byung-Soo Kim2 and Sungjee Kim1,3; 1Department of Chemistry, Pohang University of Science and Technology, Pohang, Korea, Republic of; 2Department of Bioengineering, Hanyang University, Seoul, Korea, Republic of; 3School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang, Korea, Republic of.
JJ5.25
Polyvalent Nucleic Acid Nanostructures: Novel Single-Entity Gene Regulation Agents.Joshua I. Cutler1, Ke Zhang1, Dan Zheng1, Evelyn Auyeung2, Andrew E. Prigodich1 and Chad A. Mirkin1,2; 1Department of Chemistry, Northwestern University, Evanston, Illinois; 2Department of Materials Science and Engineering, Northwestern University, Evanston, Illinois.
JJ5.26
Abstract Withdrawn
JJ5.27
Breast Adenocarcinoma Cell Behaviors on PLGA Nanometer Surface Features.Lijuan Zhang and Thomas J. Webster; Brown University, Providence, Rhode Island.
JJ5.28
Probing the Distance-Dependent Sensitivity of Plasmonic Biosensors Using Layer by Layer Assembly.Max Fei, Limei Tian, Ramesh C. Kattumenu and Srikanth Singamaneni; Mechanical Engineering and Material Sciences, Washington University in St. Louis, Saint Louis, Missouri.
JJ5.29
Gold-Iron Oxide Bifunctional Nanoparticles for Dual Diagnostic Imaging of Pancreatic Cancer.Don N. Ho1, Zhenglong Yuan2, Kai Cheng1, Edward Walsh3, Maureen Chung2 and Shouheng Sun1; 1Chemistry Department, Brown University, Providence, Rhode Island; 2Departmentof Surgery, Warren Alpert Medical School, Providence, Rhode Island; 3Department of Neuroscience, Brown University, Providence, Rhode Island.
JJ5.30
Plasmonic Paper as a Novel Biosensing Platform. Limei Tian, Ramesh Kattumenu and Srikanth Singamaneni; Mechanical Engineering and Materials Science, Washington University in St.Louis, St.Louis, Missouri.
JJ5.31
Poly(Ethylene Glycol) - Polycaprolactone Diblock Micelles with RGD Targeting Ligands and Embedded Iron Oxide Nanoparticles for Thermally-Activated Release of Doxorubicin.Christopher S. Brazel1, James B. Bennett1, Amanda L. Glover2, Jacqueline A. Nikles3, Maaike Everts4, Joel N. Glasgow4 and David E. Nikles2; 1Chemical and Biological Engineering, The University of Alabama, Tuscaloosa, Alabama; 2Chemistry, The University of Alabama, Tuscaloosa, Alabama; 3Chemistry, The University of Alabama at Birmingham, Birmingham, Alabama; 4Medicine, The University of Alabama at Birmingham, Birmingham, Alabama.
JJ5.32
Stable Colloids of Paclitaxel Nanoparticles Coated with PEGylated Polyelectrolytes Shells.Tatsiana Shutava1, Kirill Arapov1, Pravin Pattekari1, Yuri Lvov1, Tatyana Levchenko2, Rupa Sawant2 and Vladimir Torchilin2; 1Institute for Micromanufacturing, Louisiana Tech University, Ruston, Louisiana; 2Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts.
JJ5.33
A Virus-like Particle Platform for Affinity Selection and Targeted Delivery of Therapeutics.Mekensey D. Buley1, Carlee Ashley2, Walker Wharton3, David Peabody4 and Jeffrey Brinker5,6; 1Biomedical Engineering, University of New Mexcio, Albuquerque, New Mexico; 2Biotechnology and Bioengineering, Sandia National Labs, Albuquerque, New Mexico; 3Pathology, University of New Mexico, Albuquerque, New Mexico; 4Molecular Genetics and Microbiology, University of New Mexico, Albuquerque, New Mexico; 5Sandia National Labs, Albuquerque, New Mexico; 6Chemical and Nuclear Engineering, University of New Mexico, Al, New Mexico.
JJ5.34
Cytotoxic and Anti-Cancer Effects of Nickel Nanowires against Pancreatic Cancer Cells.Md. Zakir Hossain1, Wisam J. Khudhayer2, Rozina Akter1, Tansel Karabacak3 and Maurice G. Kleve4; 1Applied Biosciences, Department of Applied Science, University of Arkansas at Little Rock, Little Rock, Arkansas; 2Department of Systems Engineering, University of Arkansas at Little Rock, Little Rock, Arkansas; 3Department of Applied Science, University of Arkansas at Little Rock, Little Rock, Arkansas; 4Department of Biology, University of Arkansas at Little Rock, Little Rock, Arkansas.
JJ5.35
Symmetry Breaking of Plasmonic Nanoparticles in a Solution.Eunhye Jeong1, Kihoon Kim1, Younggeun Park1, Yeonho Choi2, Hyunjoo Lee3 and Taewook Kang1; 1Sogang University, Seoul, Korea, Republic of; 2Korea University, Seoul, Korea, Republic of; 3Yonsei University, Seoul, Korea, Republic of.
JJ5.36
Low Power, Biologically Benign NIR Light Triggers Polymer Backbone Disassembly.Adah Almutairi and Nadezda Fomina; University of California San Diego, La Jolla, California.
JJ5.37
Abstract Withdrawn
JJ5.38
Förster Resonance Energy Transfer Detection of DNA Hybridization and Fluorescence Imaging of Live Cells Using Hydroxylated Nanocrystals. Seung Koo Shin, Yongwook Kim and Hye-Joo Yoon; Chemistry, POSTECH, Pohang, Korea, Republic of.
JJ5.39
DOX-Loaded Magnetic PLGA Nanoparticles as Possible Platforms in the Detection and Therapy of Cancer.Eliana Quartarone1, Elisa Elentri1, Piercarlo Mustarelli1, Livia Visai2, Pietro Galinetto3 and Patrizia Canton4; 1Dept of Chemistry, University of Pavia, Pavia, Italy; 2Dept of Biochemistry, University of Pavia, Pavia, Italy; 3Dept of Physics, University of Pavia, Pavia, Italy; 4Dept. of Molecular Sciences and Nanosystems, University of Venezia, Pavia, Italy.
JJ5.40
Biologically Active siRNA-Based Nanostructured Particles for Efficient Gene Silencing.Cheol Am Hong1, Soo Hyeon Lee1, Jee Seon Kim1, Ji Won Park1, Ki Hyun Bae1, Yoon Sung Nam1,2, Haeshin Lee3 and Tae Gwan Park1; 1Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Korea, Republic of; 2Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea, Republic of; 3Department of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon, Korea, Republic of.
JJ5.41
Artificial Triggering of Cell Signaling and Growth via Magnetic Nanoparticles.Mi Hyeon Cho1, Jae-Hyun Lee1, Eun Jung Lee1,2, Jeon-Soo Shin2 and Jinwoo Cheon1; 1Department of Chemistry, Yonsei University, Seoul, Korea, Republic of; 2Department of Microbiology, College of Medicine, Yonsei University, Seoul, Korea, Republic of.
JJ5.42
Accurate Cell Tracking with Hybrid-Nanoparticle Based MR Contrast Agent.Tae-Hyun Shin, Jin-sil Choi, Dongwon Yoo and Jinwoo Cheon; Department of Chemistry, Yonsei University, Seoul, Korea, Republic of.
JJ5.43
Quantifying the Single Cell Traction Force by Aligned Silicon Nanowire Array.Zhou Li1,2, Jinhui Song2 and ZhongLin Wang2; 1Beihang University, BeiJing, China; 2Georgia Institute of Technology, Atlanta, Georgia.
JJ5.44
Multicomponent Mesoporous Silica Nanoparticles from Surfactant Self-Assembly.Hiroaki Sai1, Teeraporn Suteewong2, Sol M. Gruner3, Michelle Bradbury2 and Ulrich Wiesner1; 1Materials Science and Engineering, Cornell University, Ithaca, New York; 2Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York; 3Physics, Cornell University, Ithaca, New York.
JJ5.45
Folate Modified Silica Nanoparticles for Targeted Drug Delivery.Fabiola Porta1, Nabila Bardine2, Gerda Lamers3, Antony Durston2, Jeffrey Zink4 and Alexander Kros1; 1Soft Condensed Matter, Leiden University, Leiden, Netherlands; 2Molecular Biology, Leiden University, Leiden, Netherlands; 3Institute of Biology, Leiden University, Leiden, Netherlands; 4Chemistry and biochemistry, UCLA, Los Angeles, California.
JJ5.46
Gold/Silver Coated Core@Shell Magnetic Nanomaterials: Fabrication, Characterization, and Biomedical Applications.Lingyan Wang, Jin Luo, Shiyao Shan, Elizabeth Crew, Jun Yin and Chuan-Jian Zhong; Department of Chemistry, State University of New York at Binghamton, Binghamton, New York.
JJ5.47
Rapid Diagnosis of Escherichia Coli O157:H7 Using Carbon Nano Tube Field Effect Transistor (CNT-FET) Direct Binding Assay. Sung-Jae Chung1, Man Kim1, Woo Jae Park2, Steingrimur Stefansson1 and Saeyoung Ahn1; 1FTI, Rockville, Maryland; 2Mclean High School, Mclean, Virginia.
JJ5.48
Plasmonic Biosensors with Composite Nanosilver Structures.Georgios A. Sotiriou, Christoph O. Blattmann and Sotiris E. Pratsinis; Particle Technology Laboratory, ETH Zurich, Zurich, Switzerland.
JJ5.49
SEM and STEM Imaging to Accurately Locate Nanoparticles within Biological Systems.Paul J. Kempen1, Moritz F. Kircher2, Sanjiv S. Gambhir3 and Robert Sinclair1; 1Materials Engineering and Science, Stanford University, Stanford, California; 2Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York; 3Molecular Imaging Program in Radiology and Bioengineering, Stanford University, Stanford, California.
JJ5.50
Tranferred to JJ3.8
JJ5.51
Carbon Nanotube Based Multifunctional Endoscopes for Single Cell Analysis and Microfluidic Separation.Riju Singhal1, Zulfiya Orynbayeva2, Jun Jie Niu3, Michael Schrlau1, Vadym Mochalin1, Gary Friedman4 and Yury Gogotsi1; 1Materials Science and Engineernig, Drexel University, Philadelphia, Pennsylvania; 2Surgery Department, Drexel University College of Medicine, Philadelphia, Pennsylvania; 3Materials Science and Engineering, University of Pennsylvania, Philadelphia, Pennsylvania; 4Electrical and Computer Engineering, Drexel University, Philadelphia, Pennsylvania.
JJ5.52
Fabraction of Chitosan Microspheres Containing Anionic Proteins by Electrospinning.Eunju Jo, Ji Suk Choi, Hye Sung Kim, Young Ju Son, Sujin Yoon, Younghee Kim and Hyuk Sang Yoo; Biomaterials Engineering, Kangwon National University, Chuncheon, Korea, Republic of.
JJ5.53
The Study of Normal and Cancer Cells by Scanning Force Modulation Microscopy.Chungchueh Chang1, Marcia Simon2 and Miriam Rafailovich1; 1Materials Science and Engineering, SUNY at Stony Brook, Stony Brook, New York; 2Oral Biology and Pathology, SUNY at Stony Brook, Stony Brook, New York.
JJ5.54
Microemulsion Synthesis of Fe/Fe3O4@SiO2-NH2 Magnetic Nanoparticles and Studying of Their Physicochemical Properties and Stability.Katsiaryna Kekalo, Ian Baker, Katherine Koo and Evan Zeitchick; Dartmouth college, Hanover, New Hampshire.
JJ5.55
Theragnostic Nanocarrier Prepared with Tri-Fuctional Enzymes.Hee-su Kwon, Sung-Geun Jung and Young-Rok Kim; Graduate school of biotechnology, Kyung Hee university, Yong-In, Kyung gi-do, Korea, Republic of.
SESSION JJ6: Nucleic Acids in Detection and Drug Delivery
Chair: Wenbin Lin
Wednesday Morning, November 30, 2011
Room 203 (Hynes)
8:30 AM *JJ6.1
Systemic Delivery of siRNA to Solid Tumors via Targeted Nanoparticles: Preclinical to Clinical.Mark E. Davis, Chemical Engineering, California Institute of Technology, Pasadena, California.
9:00 AM JJ6.2
Structure and Properties of DNA Functionalized on the Surface. Yaroslava G. Yingling and Abhishek Singh; Materials Science and Engineering, North Carolina State University, Raleigh, North Carolina.
9:15 AM JJ6.3
Polyvalent DNA-Functionalized Gold Nanoparticles as Selective Agents for MicroRNA Detection and Regulation.Ali H. Alhasan1,2, Andrew E. Prigodich1,2, Pinal C. Patel1,2, Liangliang Hao1,2, Weston L. Daniel3,2, C. Shad Thaxton4,5,6 and Chad A. Mirkin3,2; 1Interdepartmental Biological Sciences Program, Northwestern University, Evanston, Illinois; 2International Institute for Nanotechnology, Northwestern University, Evanston, Illinois; 3Department of Chemistry, Northwestern University, Evanston, Illinois; 4Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois; 5Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois; 6Institute for BioNanotechnology and Medicine, Northwestern University, Chicago, Illinois.
9:30 AM JJ6.4
DNA Denaturation in the Presence of Gold Nanoparticles with Cationic Ligands.Justin Railsback1, Abhishek Singh1, Ryan C. Pearce1, Timothy E. McKnight2, Yaroslava G. Yingling1 and Anatoli V. Melechko1; 1Materials Science and Engineering, North Carolina State University, Raleigh, North Carolina; 2Engineering Science and Technology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee.
9:45 AM JJ6.5
Detection of DNA Methylation Using Nanoparticles.Albena Ivanisevic, NCSU, Raleigh, North Carolina.
10:00 AM BREAK
10:30 AM *JJ6.6
Shape and Size Specific Nanoparticle Cancer Therapies. Kevin P. Herlihy1, Mary E. Napier1 and Joseph M. DeSimone1,2,3; 1Lineberger Comprehensive Cancer Center, UNC Chapel Hill, Chapel Hill, North Carolina; 2Chemistry, University of North Carolina, Chapel Hill, North Carolina; 3Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina.
11:00 AM JJ6.7
Transport of Polar Oligonucleotide Cargos into Tumor Cells by Amphiphilic ``Striped'' Cell-Penetrating Nanoparticles.Prabhani Atukorale1, Randy Carney2, Jin-Mi Jung1, Christopher Jewell1, Francesco Stellacci2 and Darrell J. Irvine1,3; 1Mat. Sci. & Eng./Biological Eng., MIT, Cambridge, Massachusetts; 2Mat. Sci. & Eng., EPFL, Lausanne, Switzerland; 3Howard Hughes Medical Inst., Chevy Chase, Maryland.
11:15 AM JJ6.8
Multiplexed Magnetic Labeling Amplification Using Oligonucleotide Hybridization.Monty Liong, Carlos Tassa, Stanley Y. Shaw, Hakho Lee and Ralph Weissleder; Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts.
11:30 AM JJ6.9
Single Molecule Detection of Nitric Oxide Enabled by d(AT)15 DNA Adsorbed to near Infrared Fluorescent Single-Walled Carbon Nanotubes.Jingqing Zhang1, Ardemis A. Boghossian1, Paul W. Barone1, Alina Rwei1, Jong-Ho Kim1, Dahua Lin2, Daniel A. Heller1, Andrew J. Hilmer1, Nitish Nair1, Nigel F. Reuel1 and Michael S. Strano1; 1Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts; 2Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts.
11:45 AM JJ6.10
Magnetically Double Emulsion Nanocapsules for Remotely Controlled DNA Release and Cancer Cell Targeting.Shang-Hsiu Hu, Dept. of Materials Sciences and Engineering, National Chiao Tung University, Hsinchu, Taiwan, Taiwan.
SESSION JJ7: Bio-Nano-Materials for Cancer II
Chair: Piotr Grodzinski
Wednesday Afternoon, November 30, 2011
Room 203 (Hynes)
1:30 PM *JJ7.1
Blending Materials Science, Nanotechnology, and Oncology through a Physical Sciences Perspective.Larry Nagahara, Office of Physical Sciences - Oncology, National Cancer Institute, Bethesda, Maryland.
2:00 PM JJ7.2
Highly Sensitive SERS Nanoprobes Based on Hollow Au/Ag Nanoshell Embedded Silica Nanospheres for In vivo Multiplex Detection.Homan Kang, Sinyoung Jeong, Jiyoung Kim, San Kyeong, Jinjoo Chae, Bong-Hyun Jun, Ho-young Lee, Dae Hong Jeong and Yoon-Sik Lee; Seoul national university, Seoul, Korea, Republic of.
2:15 PM JJ7.3
Tantalum Oxide Nanoparticles: Modular Construction of New Contrast Agents for X-Ray/CT Medical Imaging.Robert E. Colborn, Peter Bonitatibus, Matthew Butts, Greg Goddard, Hubert Lam, Paul Buckley, Andrew Torres, Brian Lee, Paul Fitzgerald and Michael Marino; Chemical Nanotechnology, GE Global Research, Niskayuna, New York.
2:30 PM JJ7.4
Biocompatible Hybrid Plasmonic-Magnetic Nanoparticles for Bioimaging.Georgios A. Sotiriou1, Ann M. Hirt2, Pierre-Yves Lozach3, Alexandra Teleki1, Frank Krumeich1 and Sotiris E. Pratsinis1; 1Particle Technology Laboratory, ETH Zurich, Zurich, Switzerland; 2Department of Geophysics, ETH Zurich, Zurich, Switzerland; 3Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.
2:45 PM JJ7.5
Novel Core-Shell Magnetic Nanoparticles as Highly Efficient Contrasting Agents for Magnetic Resonance Detection.Huilin Shao1,2, Tae-jong Yoon1,3, Ralph Weissleder1,4 and Hakho Lee1; 1Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; 2Biophysics Program, Harvard Medical School, Boston, Massachusetts; 3Department of Applied Bioscience, CHA University, Seoul, Korea, Republic of; 4Department of Systems Biology, Harvard Medical School, Boston, Massachusetts.
3:00 PM BREAK
3:30 PM *JJ7.6
Hierarchical Nanostructured Interfaces for Enhanced Drug Delivery.Tejal Desai, Bioengineering and Therapeutic Sciences, UCSF, San Francisco, California.
4:00 PM JJ7.7
Mixed Micelles Formed from Acid- and Urea-Functional Polycarbonates for High Cargo Loading Capacity and Kinetic Stability.Wei Cheng1, Chuan Yang1, Jeremy P.K. Tan1, Amalina Ebrahim Attia1, Chloe Yi Ting Tan1, Alshakim Nelson2, James L. Hedrick2 and Yi-Yan Yang1; 1Institute of Bioengineering and Nanotechnology, Singapore, Singapore; 2IBM Almaden Research Center, San Jose, California.
4:15 PM JJ7.8
Luminescent and Magnetic Properties of Gd-Substituted β Phase-Na(Y,Gd)F4:Yb,Er up-Conversion Nanoparticles for Bio-Imaging.Ho Seong Jang, Kipil Lim and Kyoungja Woo; Korea Institute of Science and Technology, Seoul, Korea, Republic of.
4:30 PM JJ7.9
Surface Engineered Porous Silicon-Based Nanostructures for Cancer Therapy.Ester Segal1,2, Adi Balter3 and Naama Massad-Ivanir1; 1Biotechnology and Food Engineering, Technion - Israel Institute of Technology, Haifa, Israel; 2The Russell Berrie Nanotechnology Institute, Technion - Israel Institute of Technology, Haifa, Israel; 3The Inter-Departmental Program of Biotechnology, Technion - Israel Institute of Technology, Haifa, Israel.
4:45 PM JJ7.10
Maximizing the Sensitivity of SQUID Remanence Based Cancer Detection by Optimizing Superparamagnetic Nanoparticles.Dale L. Huber1, Erika J. Cooley1, Todd C. Monson1, Danielle L. Fegan2, Natalie L. Adolphi3, H. C. Bryant2, Helen J. Hathaway3, Debbie M. Lovato3, Kimberly S. Butler3, Trace E. Tessier2, Richard S. Larson3 and Edward R. Flynn2; 1Center for Integrated Nanotechnologies, Sandia National Laboratories, Albuquerque, New Mexico; 2Senior Scientific LLC, Albuquerque, New Mexico; 3University of New Mexico, Albuquerque, New Mexico.
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