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Symposium BM1 : Spatiotemporally and Morphologically-Controlled Biomaterials for Medical Applications

2016-11-28   Show All Abstracts

Symposium Organizers

Bing Xu, Brandeis University
Shawn Chen, National Institute of Biomedical Imaging and Bioengineering
Honggang Cui, The Johns Hopkins University

Symposium Support

Brandeis University, MRSEC, MilliporeSigma (Sigma-Aldrich Materials Science), Cell Press
BM1.1: Young Investigators
Session Chairs
Shawn Chen
Honggang Cui
Bing Xu
Monday AM, November 28, 2016
Hynes, Level 1, Room 102

8:30 AM - BM1.1.01
Molecular Engineering of Polymeric Materials for Innovative Medical Solutions

Shiyi Zhang 1

1 Shanghai Jiao Tong University Shanghai China

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8:45 AM - BM1.1.02
Refilling Drug-Eluting Hydrogels through Systemic Administration of Inert Prodrugs

Yevgeny Brudno 1 , David Mooney 1 , Michael Aizenberg 1

1 Harvard University Cambridge United States

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9:00 AM - BM1.1.03
Synthesis, Assembly and Characterization of POMaC Elastomer Used in Biodegradable Strain and Pressure Sensor for Tendons Recovery Monitoring

Clementine Boutry 1 , Anais Legrand 1 , Bob Schroeder 2 , Zhenan Bao 1

1 Stanford University Stanford United States, 2 Queen Mary University of London London United Kingdom

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9:15 AM - BM1.1.04
Design of Self-Assembling Bio-Inks for Cell-Based 3D Printing

Karen Dubbin 1 , Yuki Hori 1 , Kazuomori Lewis 1 , Sarah Heilshorn 1

1 Stanford University Stanford United States

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9:30 AM - BM1.1.05
Enzyme-Triggered Peptide Folding and Self-Assembly of Phosphopeptides

Junfeng Shi 1 , Joel Schneider 1

1 National Cancer Institute Frederick United States

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9:45 AM - BM1.1.06
Programmable Self-Assembly of Peptide-Polymer Hybrid Hydrogels

Daniel Aili 1 , Christopher Aronsson 1 , Robert Selegard 1 , Staffan Danmark 1

1 Department of Physics, Chemistry and Biology Linköping University Linköping Sweden

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10:00 AM - *
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10:30 AM - BM1.1.07
Tie Up Actin Cytoskeleton to Suppress Cancer Metastasis

Ye Zhang 1

1 Okinawa Institute of Science and Technology Kunigami-gun Japan

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10:45 AM - BM1.1.08
Three-Dimensional Micro-Patterning of Biodegradable Polymers for Controlled Drug Delivery

Thanh Nguyen 1 , Robert Langer 2

1 University of Connecticut Storrs United States, 2 Koch Institute Massachusetts Institute of Technology Cambridge United States

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11:00 AM - BM1.1.09
Membrane-Embedded Nanoparticles Facilitate the Rapid Translocation of Charged Species across Lipid Bilayers

Reid Van Lehn 1

1 University of Wisconsin-Madison Madison United States

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11:15 AM - BM1.1.10
Micro-Robotic Devices for Localized Actuation and Selective Positioning in the Gastrointestinal Tract

Jinxing Li 1 , Soracha Kun Thamphiwatana 1 , Liangfang Zhang 1 , Joseph Wang 1

1 University of California, San Diego La Jolla United States

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11:30 AM - *BM1.1.11
Targeting Siglecs with a Sialic Acid-Decorated Nanoparticle Abrogates Inflammation

Michelle Greene 1 , Shaun Spence 1 , Francois Fay 3 , Emily Hams 2 , Sean Saunders 2 , Umar Hamid 1 , Marianne Fitzgerald 1 , Cecilia O'Kane 1 , Denise Fitzgerald 1 , James Johnston 4 , Padraic Fallon 2 , Daniel McAuley 1 , Adrien Kissenpfennig 1 , Christopher Scott 1

1 Queen's University Belfast Belfast United Kingdom, 3 Icahn School of Medicine at Mount Sinai New York United States, 2 Trinity College Dublin Dublin Ireland, 4 Amgen Inc. Thousand Oaks United States

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BM1.2: Nanostructures
Session Chairs
Shawn Chen
Honggang Cui
Bing Xu
Monday PM, November 28, 2016
Hynes, Level 1, Room 102

1:30 PM - *BM1.2.01
Surface-Engineered Nanocrystals—Synthesis, Assembly, and Applications

Peng Wang 1 , Qirong Xiong 1 , Jiajing Zhou 1 , Hongwei Duan 1

1 Nanyang Technological University Singapore Singapore

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2:00 PM - *BM1.2.02
Membrane Fusion Delivery of siRNA Using Nanoparticle Nanocapsules—Applications of Direct Cytosol Delivery In Vitro and In Vivo

Vincent Rotello 1

1 University of Massachusetts Amherst United States

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2:30 PM - BM1.2.03
Diagnosis of Tropical Viruses Using Gold Nanoparticles in Lateral Flow Immunoassays

Helena de Puig Guixe 1 , Marc Carre-Camps 1 , Irene Bosch 1 , Kimberly Hamad-Schifferli 2 , Lee Gehrke 1

1 Massachusetts Institute of Technology Cambridge United States, 2 University of Massachusetts Boston United States

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2:45 PM - BM1.2.04
Overcoming the Blood-Brain Barrier—Post-Resection Drug Delivery to Glioblastoma Multiforme Using Supramolecular Hydrogels

Oren Scherman 1

1 University of Cambridge Cambridge United Kingdom

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3:00 PM - *
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3:30 PM - *BM1.2.05
Intra-Mitochondrial Assembly of Peptide Amphiphiles as Novel Cancer Therapy

Ja-Hyoung Ryu 1 , M. T. Jeena 1

1 Ulsan National Institute of Science and Technology Ulsan Korea (the Republic of)

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4:00 PM - *BM1.2.06
Durable Bio-Inert Coating for Biomedical Applications

Xinhua Li 1

1 Nano Terra, Inc Cambridge United States

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4:30 PM - *BM1.2.07
The Art of Falling Apart—Exploiting Nanomaterial Disassembly for Health Sciences

Adah Almutairi 1

1 University of California, San Diego La Jolla United States

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2016-11-29   Show All Abstracts

Symposium Organizers

Bing Xu, Brandeis University
Shawn Chen, National Institute of Biomedical Imaging and Bioengineering
Honggang Cui, The Johns Hopkins University

Symposium Support

Brandeis University, MRSEC, MilliporeSigma (Sigma-Aldrich Materials Science), Cell Press
BM1.3: Responsive Materials
Session Chairs
Shawn Chen
Honggang Cui
Bing Xu
Tuesday AM, November 29, 2016
Hynes, Level 1, Room 102

8:30 AM - *BM1.3.01
From Nano to Micro and Back—Porphyrin Supramolecular Assembly for Cancer Imaging and Therapy

Gang Zheng 1 2

1 Department of Medical Biophysics University of Toronto Toronto Canada, 2 Princess Margaret Cancer Centre Toronto Canada

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9:00 AM - *BM1.3.02
From Filomicelles to 'Self' Recognition

Dennis Discher 1

1 University of Pennsylvania Philadelphia United States

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9:30 AM - *BM1.3.03
Target-Enabled In Situ Ligand Assembly (TESLA) for Molecular Imaging Applications

Jianghong Rao 1

1 Stanford University Palo Alto United States

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10:00 AM - *
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10:30 AM - *BM1.3.04
Soft Functional Actuators—Biomemetics and Materials

George Whitesides 1

1 Department of Chemistry and Chemical Biology Harvard University Cambridge United States

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11:00 AM - *BM1.3.05
Fuel-Driven Active Materials

Jan van Esch 1 , Wouter Hendriksen 1 , R. Eelkema 1 , G. Koper 1

1 Department of Chemical Engineering Delft University of Technology Delft Netherlands

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11:30 AM - *BM1.3.06
Responsive Nanoassemblies

Sankaran Thayumanavan 1

1 University of Massachusetts Amherst United States

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BM1.4: Materials for Medicine
Session Chairs
Shawn Chen
Honggang Cui
Bing Xu
Tuesday PM, November 29, 2016
Hynes, Level 1, Room 102

1:30 PM - *BM1.4.01
Translational Anticancer Nanomedicines through Controlled Chemistry

Jianjun Cheng 1 , Hua Wang 2

1 University of Illinois at Urbana-Champaign Urbana United States, 2 Harvard University Cambridge United States

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2:00 PM - *BM1.4.02
Role of Nanoparticle Morphology in Crossing Biological Barriers

Samir Mitragotri 1

1 University of California, Santa Barbara Santa Barbara United States

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2:30 PM - *BM1.4.03
Artificial Spores—Cytocompatible Nanoencapsulation of Individual Living Cells

Insung Choi 1

1 KAIST Daejeon Korea (the Republic of)

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3:00 PM - *
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3:30 PM - *BM1.4.04
Nanolayered Staged Delivery Approaches to Trauma Treatment and Wound Healing

Paula Hammond 2 1

2 Department of Chemical Engineering Massachusetts Institute of Technology Cambridge United States, 1 Koch Institute of Integrative Cancer Research Massachusetts Institute of Technology Cambridge United States

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4:00 PM - *BM1.4.05
A Powerful CD8+ T-Cell Stimulating D-Tetra-Peptide Hydrogel as a Very Promising Vaccine Adjuvant

Huaimin Wang 1 , Chengbiao Yang 1 , Zhimou Yang 1

1 Nankai University Tianjin China

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4:30 PM - *BM1.4.06
Inverse Opal Scaffolds for Tissue Engineering and Regenerative Medicine

Younan Xia 1

1 Georgia Institute of Technology Atlanta United States

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2016-11-30   Show All Abstracts

Symposium Organizers

Bing Xu, Brandeis University
Shawn Chen, National Institute of Biomedical Imaging and Bioengineering
Honggang Cui, The Johns Hopkins University

Symposium Support

Brandeis University, MRSEC, MilliporeSigma (Sigma-Aldrich Materials Science), Cell Press
BM1.5: Hydrogels
Session Chairs
Shawn Chen
Honggang Cui
Bing Xu
Wednesday AM, November 30, 2016
Hynes, Level 1, Room 102

8:30 AM - *BM1.5.01
Structure and Function of Hydrogels Comprising Self-Sorted Supramoleular Fibers

Itaru Hamachi 1 2

1 Kyoto University Kyoto Japan, 2 CREST/JST Tokyo Japan

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9:00 AM - *BM1.5.02
A Multi-Phase Transitioning Peptide Hydrogel for Suturing Ultra-Small Vessels

Joel Schneider 1

1 National Cancer Institute Frederick United States

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9:30 AM - *BM1.5.03
Dynamic Peptide-DNA Materials

Samuel Stupp 1

1 Northwestern University Evanston United States

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10:00 AM - *
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10:30 AM - *BM1.5.04
Dynamic Peptide Libraries for Discovery of Supramolecular Nanomaterials

Rein Ulijn 1

1 The City University of New York Glasgow United Kingdom

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11:00 AM - *BM1.5.05
Synthesis, Design, and Assembly of Spatiotemporally-Controlled Hyaluronan Hydrogels

Molly Shoichet 1 , Stephanie Fisher 1 , Alexander Baker 1 , Roger Tam 1 , Laura Smith 1

1 Department of Chemical Engineering and Applied Chemistry University of Toronto Toronto Canada

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11:30 AM - *BM1.5.06
Intracellular Self-Assembly of a Low-Molecular-Weight Gelator Induces Selective Death of Cancer Cells

Tatsuo Maruyama 1 , Akiko Tanaka 1

1 Kobe University Kobe Japan

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BM1.6: Emerging Leaders
Session Chairs
Shawn Chen
Honggang Cui
Bing Xu
Wednesday PM, November 30, 2016
Hynes, Level 1, Room 102

1:30 PM - *BM1.6.01
Small and Bright—Functional Luminescent Nanoparticles for Bioimaging and Optogenetic Applications

Gang Han 1

1 Medical School University of Massachusetts Worcester United States

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2:00 PM - *BM1.6.02
Overcoming the Intrinsic Biopharmaceutical Difficulties of Oligonucleotides and Chemotherapeutics with Their Combination

Ke Zhang 1

1 Northeastern University Boston United States

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2:30 PM -
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3:30 PM - *BM1.6.03
Self-Assembly of Hybrid Assemblies for Cancer Imaging and Therapy

Zhihong Nie 1

1 University of Maryland College Park United States

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4:00 PM - BM1.6.04
Nanomaterial Mimicry of the Metastatic Niche

Daniel Heller 1 2

1 Memorial Sloan-Kettering Cancer Center New York United States, 2 Weill Cornell Medical College New York United States

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4:15 PM - BM1.6.05
3D Printing of Alginate Microstructures with Tunable Degradation Kinetics

Thomas Valentin 1 , Po-Yen Chen 1 , Jaskiranjeet Sodhi 1 , Susan Leggett 1 , Hayley Mcclintock 1 , Ian Wong 1

1 Brown University Providence United States

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4:30 PM - BM1.6.06
Supramolecular Biomaterials—From Fundamentals to Advanced Healthcare Solutions

Eric Appel 1

1 Department of Materials Science amp; Engineering Stanford University Stanford United States

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4:45 PM - BM1.6.07
Programming Immune Tolerance Using Quantum Dots to Control Self-Antigen Display

Christopher Jewell 1 2 3

1 Fischell Department of Bioengineering University of Maryland, College Park College Park United States, 2 Department of Microbiology and Immunology University of Maryland School of Medicine Baltimore United States, 3 Tumor Immunology and Immunotherapy Program Marlene and Stewart Greenebaum Cancer Center Baltimore United States

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BM1.7: Poster Session I
Session Chairs
Wednesday PM, November 30, 2016
Hynes, Level 1, Hall B

8:00 PM - BM1.7.01
Synthesis and Characterization of Bioinspired Dynamic Materials and Their Application in Oral Drugs Delivery

Saad Alshehri 1 , Tansir Ahamad 1

1 King Saud University Riyadh Saudi Arabia

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8:00 PM - BM1.7.02
Surface Enhanced Raman Spectroscopy in the Prescense of Hydroquinone Assisted by Gold Nanorods

Rodrigo Cabrera Alonso 1 , Francisco Javier Gonzalez Contreras 1

1 Coordination for the Innovation and Application of Science and Technology San Luis Potosí Mexico

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8:00 PM - BM1.7.03
Novel Nanoprobes Optimized by Peptide Self-Assembly for Bioimaging Applications

Yanbin Cai 1 , Zhimou Yang 1

1 Nankai University Tianjin China

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8:00 PM - BM1.7.04
Bioresponsive Conductive Polymer Based on Carbon Nanotube-Hydrogel Composites

Bo Wu 1 , Li-Jing Cheng 1 , Akash Kannegulla 1

1 Oregon State University Corvallis United States

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8:00 PM - BM1.7.05
Understanding the Self-Assembly of Micelles and Micelle Networks Formed by an Array of Amphiphilic Macromolecules Using Dissipative Particle Dynamics

Thomas Deaton 1 , Nan Li 1 , Yaroslava Yingling 1

1 North Carolina State University Raleigh United States

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8:00 PM - BM1.7.06
Nanobody-Conjugated, Quantum Dot-Based Unimolecular Micelles for Targeted Triple Negative Breast Cancer Therapy

Yuyuan Wang 3 1 , Yidan Wang 2 , Guojun Chen 3 1 , Yitong Li 4 , Wei Xu 2 6 , Shaoqin Gong 1 5

3 Department of Materials Science and Engineering University of Wisconsin–Madison Madison United States, 1 Wisconsin Institutes for Discovery University of Wisconsin–Madison Madison United States, 2 McArdle Laboratory for Cancer Research University of Wisconsin–Madison Madison United States, 4 Department of Chemistry Tsinghua University Beijing China, 6 Molecular and Environmental Toxicology Center University of Wisconsin–Madison Madison United States, 5 Department of Biomedical Engineering University of Wisconsin–Madison Madison United States

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8:00 PM - BM1.7.07
Multilayer Core-Shell Lanthanide Nanoparticles for Biomedical Diagnostic and Therapeutic Applications

Sha He 1 , Noah Johnson 2 , Viet Anh Nguyen Huu 1 , Yuran Huang 3 , Adah Almutairi 1 2 3

1 Department of Nanoengineering University of California, San Diego La Jolla United States, 2 Skaggs School of Pharmacy and Pharmaceutical Sciences University of California, San Diego La Jolla United States, 3 Materials Science and Engineering Program University of California, San Diego La Jolla United States

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8:00 PM - BM1.7.08
pH-Sensing Drug Delivery System Using Anionic Copolymers

Bahman Homayun 1 , Ankit Kumar 1 , Chengmeng Sun 1 , Hyo-Jick Choi 1 , Carlo Montemagno 1

1 Chemical and Materials Engineering Department University of Alberta Edmonton Canada

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8:00 PM - BM1.7.09
Development of Polyion Complex Vesicles (PICsomes) with Various Side-Chain Modifications for Stability Enhancement under the Physiological Salt Condition

Mao Hori 1 , Yasutaka Anraku 1 3 , Akihiro Kishimura 2 , Kazunori Kataoka 3

1 Graduate School of Engineering University of Tokyo Bunkyo-ku Japan, 3 Innovation Center of NanoMedicine Kawasaki Japan, 2 Faculty of Engineering Kyushu University Nishi-ku Japan

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8:00 PM - BM1.7.10
Scaffolds for Respiratory Infection Profiling and Diagnosis

Paul Jones 1 , Pamela Pruski 2 , Trevor Hansel 3 , Zoltan Takats 2 , Julian Jones 1

1 Department of Materials Imperial College London London United Kingdom, 2 Department of Surgery amp; Cancer Imperial College London London United Kingdom, 3 National Heart amp; Lung Institute Imperial College London London United Kingdom

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8:00 PM - BM1.7.11
Development of Multimodality Imaging System Using Self-Assembled Polymer Nanocapsule

Sungwan Kim 1 , Gyeongwon Yun 2 , Kyeng Min Park 2 , Suman Khan 1 , Jinhwan Kim 1 , Yeong Mi Lee 2 , Dinesh Shetty 2 , Won Jong Kim 1 2 , Kimoon Kim 1 2

1 POSTECH Pohang Korea (the Republic of), 2 Institute for Basic Science Pohang Korea (the Republic of)

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8:00 PM - BM1.7.12
Efficient and Selective Removal of Human Pluripotent Stem Cells via Ecto-Alkaline Phosphatase-Mediated Aggregation of Synthetic Peptides

Yi Kuang 1 , Kenji Miki 1 , Callum Parr 1 , Karin Hayashi 1 , Hirohide Saito 1

1 Kyoto University Kyoto Japan

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8:00 PM - BM1.7.13
Enzyme-Orientated Self-Assembly of Metallo-Hydrogelator on Membrane Protrusion

Guanying Li 1 , Ye Zhang 1

1 Okinawa Institute of Science and Technology Graduate University Okinawa Japan

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8:00 PM - BM1.7.14
Programmable Orthogonal Hydrogels for Time-Staggered Delivery of Dual Chemotherapeutics

Poulami Majumder 1 , Ulrich Baxa 2 3 , Joel Schneider 1

1 Chemical Biology Laboratory, Center for Cancer Research National Cancer Institute Frederick United States, 2 Electron Microscopy Laboratory Leidos Biomedical Research, Inc Frederick United States, 3 Nanotechnology Characterization Laboratory National Cancer Institute Frederick United States

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8:00 PM - BM1.7.15
Nanodiamond Mediated Enhanced Endothelial Permeability for Drug Delivery

Vadym Mochalin 1 , Magdiel Setyawati 2 , David Leong 2

1 Missouri University of Science and Technology Rolla United States, 2 Chemical and Biomolecular Engineering National University of Singapore Singapore Singapore

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8:00 PM - BM1.7.16
Red Blood Cell Surface Modification by Metal-Polyphenol Complex for Immunocamouflage

Taegyun Park 1 , Kyungtae Kang 2 , Insung Choi 1

1 Korea Advanced Institute of Science and Technology Daejeon Korea (the Republic of), 2 Kyung Hee University Yongin Korea (the Republic of)

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8:00 PM - BM1.7.17
Bottom-Up Synthesis of Silica/PCL Hybrids for Future Bone Regeneration

Tian Sang 1 , Remzi Becer 2 , Julian Jones 1

1 Materials Imperial College London London United Kingdom, 2 School of Engineering and Materials Science Queen Mary University of London London United Kingdom

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8:00 PM - BM1.7.18
Supramolecular Nanotubes by Anticancer Drug Assembly

Hao Su 1 , Zhantong Wang 2 , Shawn Chen 2 , Honggang Cui 1

1 Chemical and Biomolecular Engineering and Institute for Bionanotechnology Johns Hopkins University Baltimore United States, 2 Laboratory of Molecular Imaging and Nanomedicine National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health Bethesda United States

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8:00 PM - BM1.7.19
Introduction of a Regulated Transcriptional Circuit into Cells Using Multifunctional Layer-by-Layer Assembled Microcapsules

Dheemanth Vangimalla 1 , Dong Luo 2 , Samantha Gabriel 2 , Gleb Sukhorukov 2 , David Gould 1

1 William Harvey Research Institute Queen Mary University of London London United Kingdom, 2 School of Engineering and Materials Science Queen Mary University of London London United Kingdom

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8:00 PM - BM1.7.20
Drug-Based Supramolecular Nanotubes as Effective Drug Carriers

Yin Wang 1 , Pengcheng Zhang 1 , Ran Lin 1 , Honggang Cui 1

1 Chemical and Biomolecular Engineering Johns Hopkins University Baltimore United States

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8:00 PM - BM1.7.21
Automated Control of Magneto-Thermally Responsive Soft Grippers for Pick-and-Place of Biological Cargo

ChangKyu Yoon 1 , Federico Ongaro 2 , Stefano Scheggi 2 , Seung Hyun Oh 4 , Sarthak Misra 2 3 , David Gracias 1 4

1 Materials Science and Engineering Johns Hopkins University Baltimore United States, 2 Biomechanical Engineering University of Twente Enschede Netherlands, 4 Chemical and Biomolecular Engineering Johns Hopkins University Baltimore United States, 3 Biomedical Engineering University of Groningen and University Medical Center Groningen Groningen Netherlands

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8:00 PM - BM1.7.22
Hyper Crosslinkers Confer Dual Responsive Polymeric Nanogels Exhibiting an Unexpected Shape Change to Temperature

Ning Zhou 1 , Xiaoyan Cao 1 , Klaus Schmidt-Rohr 1 , Bing Xu 1

1 Brandeis University Waltham United States

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8:00 PM - BM1.7.23
Morphologically Controlled Conducting Polymers for Biosensors and Bioelectronics

Martin Antensteiner 1 , Thao Nguyen 1 , Chandra Mohan 1 , Mohammad Reza Abidian 1

1 University of Houston Houston United States

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8:00 PM - BM1.7.24
Fluorescently Surface Charged Nano-Liposomes Reveal Unexpected Internalization Pattern among Various Immune Cells—A Step Towards Better Targeted Cancer Nano-Immunotherapy

Noha Ismail 1 2 , Nageh Allam 1 , Suher Zada 1 , Ashish Kulkarni 2 , Shiladitya Sengupta 2

1 American University in Cairo Cairo Egypt, 2 Harvard-MIT Health Sciences and Technology Harvard Medical School Cambridge United States

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