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Symposium D: Biosurfaces and Biointerfaces

November 27 - December 1, 2006

Chairs

John A. Carlisle		Argonne National Laboratory
Martin Eickhoff		Technische Universitaet Muenchen
Jose A. Garrido		Technische Universitaet Muenchen
Janos Voeroes		University and ETH Zurich
Erika Johnston		Genzyme Corporation

Symposium Support

Genzyme Corporation Q-Sense, Inc.

SESSION D1: Nanobiotechnology
Chair: John Carlisle
Monday Morning, November 27, 2006
Room 202 (Hynes)
8:30 AM *D1.1
Bionanoarrays Prepared by Massive Parallel Dip-Pen Nanolithography Chad Mirkin^1,2, Khalid Salaita^1,2, Yuhuang Wang^1,2, Rafael Vega^1,2, Joseph Kakkassery^1,2, Clifton Shen^1,2 and Daniel Maspoch^1,2; ¹International Institute for Nanotechnology, Northwestern University, Evanston, Illinois; ²Department of Chemistry, Northwestern University, Evanston, Illinois.

9:00 AM D1.2
Lab-on-a-Chip Devices with Nanoscale Surface Topography for Neural Electrophysiological Applications. Ludovico M. Dell'Acqua-Bellavitis^1,3 and Richard W. Siegel^2,3; ¹Engineering Science, Rensselaer Polytechnic Institute, Troy, New York; ²Materials Science and Engineering, Rensselaer Polytechnic Institute, Troy, New York; ³Nanotechnology Center, Rensselaer Polytechnic Institute, Troy, New York.

9:15 AM D1.3
Stack of BioCells Converting ATP to Electrical Power and Possible Applications. Vishnu Baba Sundaresan, Donald Leo and Andy Stephen Sarles; Mechanical Engineering Department, Virginia Tech, Blacksburg, Virginia.

9:30 AM D1.4
Use of sub-10 nm Diameter Upconversion Nanophosphors as Bio-labels. Shuang Fang Lim¹, Robert Riehn¹, Chih-kuan Tung¹, David W. Tank¹, Robert H. Austin¹, William S. Ryu², Margarita Herrera-Alonso³ and Robert K. Prud'homme³; ¹Physics, Princeton University, Princeton, New Jersey; ²Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey; ³Chemical Engineering, Princeton University, Princeton, New Jersey.

9:45 AM BREAK

SESSION D2: Nanoparticles
Chair: John Carlisle
Monday Morning, November 27, 2006
Room 202 (Hynes)
10:15 AM *D2.1
Modular Designed Functional Nanoparticles for Clinical Theranostics. Dar-Bin Shieh¹, Cheng-Shen Yeh² and Yonhua Tommy Tzeng^3,4; ¹Institute of Oral Medicine and Center for Micro/Nano Science and Technology, National Cheng Kung University, Tainan, Taiwan; ²Department of Chemistry and Center for Micro/Nano Science and Technology, National Cheng Kung University, Tainan, Taiwan; ³Institute of Nanotechnology and Microsystems Engineering and Center for Micro/Nano Science and Technology, National Cheng Kung University, Tainan, Taiwan; ⁴Dept. of Electrical & Computer Engineering, Auburn University, Auburn University, Alabama.

10:45 AM D2.2
Gold Nanoparticle Covalent Labeling of Proteins at Specific Sites. Marie-Eve Aubin-Tam¹ and Kimberly Hamad-Schifferli^2,1; ¹Biological Engineering Department, Massachusetts Institute of Technology, Cambridge, Massachusetts; ²Mechanical Engineering Department, Massachusetts Institute of Technology, Cambridge, Massachusetts.

11:00 AM D2.3
Abstract Withdrawn

11:15 AM D2.4
Fluorescent Silica Nanoparticles: Probes for Imaging and Sensing in Biology Andrew Burns¹, Prabuddha Sengupta², Ethan Chiang², Erik Herz¹, Barbara Baird² and Ulrich Wiesner¹; ¹Materials Science & Engineering, Cornell University, Ithaca, New York; ²Chemistry and Biochemistry, Cornell University, Ithaca, New York.

11:30 AM D2.5
Magnetic Nanoparticle-biomolecule Interfaces: Synthesis, Characterization, and Implementation in Bioengineering Applications. Kimberly Hamad-Schifferli, Mechanical Engineering, MIT, Cambridge, Massachusetts; Biological Engineering, MIT, Cambridge, Massachusetts.

11:45 AM D2.6
Particle Size Effects in Magnetite Nanoparticle Uptake into Cells Juan Meng¹, Patrick Clasen², Tracy Vu¹, Shuailei Ma², Christopher J. Kiely², Martin P. Harmer² and Winston O Soboyejo¹; ¹Mechanical and Aerospace Engineering, Princeton University, Princeton, New Jersey; ²Materials Science and Engineering, Lehigh University, Bethlehem, Pennsylvania.

SESSION D3: Cell Surface Interactions
Chair: John Carlisle
Monday Afternoon, November 27, 2006
Room 202 (Hynes)
1:30 PM *D3.1
Molecularly Engineered Surfaces for Cell Biology. George Whitesides, J. Jiang, D. Bruzewicz, A. McGuidon, N. Shen, A. Wong, D. Weibel, J. Kriebel and M. Butte; The Whitesides Research Group, Harvard University, Cambridge, Massachusetts.

2:00 PM D3.2
Engineering Cellular Behavior via Cell-Surface Interactions with Fibronectin Nanoislands. John Hundley Slater and Wolfgang Frey; Department of Biomedical Engineering and Center for Nano and Molecular Science and Technology, University of Texas at Austin, Austin, Texas.

2:15 PM D3.3
Application of Biomolecular Machinery for Nanoscale Device Assembly. Erik D. Spoerke, George Bachand, Haiqing Liu, John Nogan, Thomas Swiler, Subhash Shinde and Bruce Bunker; Sandia National Laboratories, Albuquerque, New Mexico.

2:30 PM BREAK

3:30 PM D3.4
Engineering Loading Stations for Cargo Pick-up by Molecular Shuttles. Christian Brunner¹, Christian Wahnes¹, Volker Jacobsen², Vahid Sandoghdar² and Viola Vogel¹; ¹Biologically-Oriented Materials, Dept. of Materials, ETH Zurich, Zurich, Switzerland; ²Nano-Optics Group, Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland.

3:45 PM D3.5
A High-Throughput-Screening Approach for Cell-Surface-Roughness Interaction. Tobias Peter Kunzler, Tanja Drobek and Nicholas D. Spencer; Material Science, Federal Institute of Technology (ETH), Zuerich, ZH, Switzerland.

4:00 PM D3.6
Engineered bio/nano Interfaces via Cell-directed Assembly. C. Jeffrey Brinker^1,2, Eric Carnes², Carlee Ashley² and Seema Singh¹; ¹Sandia Labs/UNM, Albuquerque, New Mexico; ²The University of New Mexico, Albuquerque, New Mexico.

4:15 PM D3.7
Investigation of Spreading and Adhesion of Human Osteosarcoma Cells on Smooth and Microgrooved Polydimethylsilaxone Surfaces Yifang Cao¹, Jianbo Chen² and Winston O. Soboyejo²; ¹Engineering Science Programme and Division of Bioengineering, National University of Singapore, Singapore, Singapore; ²Department of Mechanical and Aerospace Engineering and Princeton Institute for the Science and Technology of Materials (PRISM), Princeton University, Princeton, New Jersey.

4:30 PM D3.8
Cellular Traction Forces of Adult Human Dermal Fibroblasts in Response to Fibronectin Functional Domains: from Biochemical Signals to Mechanical Responses Zhi Pan¹, Kaustabh Ghosh², Yajie Liu³, Xiaozheng Shu⁵, Toshio Nakamura³, Glenn D. Prestwich⁵, Xiang-Dong Ren⁴, Richard A. F. Clark^2,4 and Miriam Rafailovich¹; ¹Materials Science & Engineering, SUNY at Stony Brook, Stony Brook, New York; ²Biomedical Engineering, SUNY at Stony Brook, Stony Brook, New York; ³Mechanical Engineering, SUNY at Stony Brook, Stony Brook, New York; ⁴Dermatology and Medicine, SUNY at Stony Brook, Stony Brook, New York; ⁵Medicinal Chemistry, University of Utah, Salt Lake City, Utah.

4:45 PM D3.9
Effect of m-Calpain Degradation on Cartilage Aggrecan Nanomechanical Properties. Lin Han¹, Delphine Dean², Han-Hwa K Hung³, John D Sandy^4,5, Christine Ortiz^1,7 and Alan J Grodzinsky^2,6,7; ¹Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts; ²Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts; ³Center for Biomedical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts; ⁴Pharmacology and Therapeutics, University of South Florida, Tampa, Florida; ⁵Shriners Hospital for Children, University of South Florida, Tampa, Florida; ⁶Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts; ⁷Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts.

SESSION D4: Poster Session
Monday Evening, November 27, 2006
8:00 PM
Exhibition Hall D (Hynes)
D4.1
Synthesis of Platinum Nanocages Using Liposomes Containing Photocatalyst Molecules, Yujiang Song¹, Robert M. Garcia^1,2, Rachel M. Dorin^1,2, Haorong Wang^1,2, Yan Qiu^1,2 and John A. Shelnutt^1,3; ¹Surface and Interface Sciences Department, Sandia National Laboratories, Albuquerque, New Mexico; ²Chemistry and Chemical & Engineering Department, The University of New Mexico, Albuquerque, New Mexico; ³Chemistry Department, University of Georgia, Athens, Georgia.

D4.2
A FRET Study on Conformational Change of Electrophoretic Nanoparticle-Polymer Conjugates Sunho Park¹ and Kimberly Hamad-Schifferli^1,2; ¹Department of Mechanical Engineering, MIT, Cambridge, Massachusetts; ²Biological Engineering Division, MIT, Cambridge, Massachusetts.

D4.3
Abstract Withdrawn

D4.4
Room Temperature Synthesis of Semiconductor, Metal, and Ferroelectric Nanoparticles Using Ring-shaped Peptide Assemblies as Nanoreactors. Nuerxiati Nueraji and Hiroshi Matsui; Department of Chemistry and Biochemistry, Hunter college and the Graduate Center, the City University of New York, New York, New York.

D4.5
Magnetic Nanoparticle Protein Conjugates: Study of Magnetic Field Heating. Joshua Alper¹, Katherine Rahlin², Marie-Eve Aubin-Tam³ and Kimberly Hamad-Schifferli^1,3; ¹Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts; ²Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts; ³Biological Engineering Division, Massachusetts Institute of Technology, Cambridge, Massachusetts.

D4.6
Delivery, Biocompatibility and Surface Chemistry of Polyamidoamine-Gold Nanocrystals for Live Cell Imaging. Victor Stephen Lelyveld¹ and Kimberly Hamad-Schifferli^2,1; ¹Biological Engineering, MIT, Cambridge, Massachusetts; ²Mechanical Engineering, MIT, Cambridge, Massachusetts.

D4.7
Encapsulation of Fe3O4 and Au Nanoparticles in Thermosensitive Liposomes: Synthesis and Applications Andy Wijaya¹ and Kimberly Hamad-Schifferli^2,3; ¹Chemical Engineering, MIT, Cambridge, Massachusetts; ²Mechanical Engineering, MIT, Cambridge, Massachusetts; ³Biological Engineering Division, MIT, Cambridge, Massachusetts.

D4.8
Charge-Directed Targeting of Antimicrobial Protein-Nanoparticle Conjugates. Rohan Satishkumar, Gary Thompson and Alexey Vertegel; Bioengineering, Clemson University, Clemson, South Carolina.

D4.9
Biocompatible Polymeric Nanoparticles and Films Containing Hydrophobic Quantum Dots. Jisook Lee, Ick Chan Kwon and Hesson Chung; Biomedical research center, KIST, Seoul, South Korea.

D4.10
Controlled Electrostatic-Based Multilayer Adsorption of Nanoparticles for Novel Coatings with Biological Activity Stoyan Smoukov, Bartosz Grzybowski, Alexander Kalsin, Bartlomiej Kowalczyk, Maciej Paszewski and Kristiana Kandere-Grzybowska; Chem. & Biol. Engineering, Northwestern University, Evanston, Illinois.

D4.11
Nanoparticle Size Effect on Human Dermal Fibroblasts. Nadine Pernodet¹, Asya Bakhtina², Jonathan Sokolov¹, Abraham Ulman², Kalle Levon² and Miriam Rafailovich¹; ¹Materials Science & Engineering, Stony Brook University, Stony Brook, New York; ²Chemical and Biological Sciences, Polytechnic University, Brooklyn, New York.

D4.12
Magnetic Field Heating of Fe3O4 Nanoparticles. Shahriar Khushrushahi¹ and Kimberly Hamad-Schifferli²; ¹Department of Electrical Engineering and Computer Science, MIT, Cambridge, Massachusetts; ²Department of Mechanical and Biological Engineering, MIT, Cambridge, Massachusetts.

D4.13
A Strong Interaction Between Chemical Functionality and Nanoscale Surface Topography Impacts Fibronectin Conformation and Neuronal Differentiation on Model Sol-gel Silica Substrates. Sabrina S. Jedlicka^1,3, Silas J. Leavesley^2,3, Kenneth M. Little⁴, J. Paul Robinson^2,3,5, David E. Nivens⁴ and Jenna L. Rickus^1,2,3; ¹Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, Indiana; ²Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana; ³Bindley Bioscience Center, Purdue University, West Lafayette, Indiana; ⁴Department of Food Science, Purdue University, West Lafayette, Indiana; ⁵Department of Basic Medical Sciences, Purdue University, West Lafayette, Indiana.

D4.14
Electronic Control of Cell Adhesion and Tissue Formation using Electronic Surface Tension Switches. Magnus Berggren¹, Kalle Svennersten², Agneta Richter-Dahlfors², Maria Bolin¹ and Nathaniel Robinson¹; ¹ITN, Linkoping University, Norrkoping, Sweden; ²MTC, Karolinska Institutet, Solna, Sweden.

D4.15
Controlling Cell Growth by Nanoparticles. Sergiy Zankovych, Joerg Bossert, Liga Berzina-Cimdina, Ines Thiele and Klaus D. Jandt; Friedrich-Schiller-University Jena, Institute of Materials Science and Technology, Jena, Germany.

D4.16
Cell Viability and Adhesion on as Grown Vertically Aligned Carbon Nanotubes. Evaldo José Corat¹, Anderson de Oliveira Lobo¹, Erica Freire Antunes¹, Cristina Pacheco Soares², Mariana Bernardes da Silva Palma^1,2 and Vladimir Jesus Trava-Airoldi¹; ¹Laboratorio Associado de Sensores e Materiais, Instituto Nacional de Pesquisas Espaciais, São José dos Campos, São Paulo, Brazil; ²Instituto de Pesquisa e Desenvolvimento, Universidade do Vale do Paraíba, São José dos Campos, São Paulo, Brazil.

D4.17
Glycosylated Polyelectrolyte Multilayer Films: Differential Adhesion of Primary Versus Tumor Cells. Aurore Schneider¹, Jean-Claude Voegel¹, Catherine Picart¹ and Benoit Frisch²; ¹INSERM U 595, Strasbourg, France; ²CNRS-ULP UMR 7514, Strasbourg, France.

D4.18
Differentiation of Bone Marrow Stem Cells on Inkjet Printed Silk Lines. Paul Calvert¹, Skander Limem¹, David Kaplan² and Hyeon Joo Kim²; ¹umass dartmouth, north dartmouth, Massachusetts; ²Tufts University, Medford, Massachusetts.

D4.19
Persistent Inhibition of Cell Growth on Silver Implanted Glassy Polymeric Carbon Robert Lee Zimmerman¹, Ismet Gurhan², Fayse Ozdal-Kurt³, B. H. Sen⁴, Marcello Rodrigues⁵ and Daryush Ila¹; ¹Center for Irradiation of Materials, Alabama A&M University, Normal, Alabama; ²Ege University Faculty of Engineering, Izmir, Turkey; ³CBU Faculty of Science, Manisa, Turkey; ⁴EU Faculty of Dentistry, Izmir, Turkey; ⁵University of São Paulo, Ribeirão Preto, SP, Brazil.

D4.20
An Enzymatically Switchable Hydrogel Surface for Controlled Cell Adhesion. Simon Todd, Rein Ulijn and Julie Gough; Materials Science Centre, University of Manchester, Manchester, United Kingdom.

D4.21
High Density Addressable Protein and Cell Patterning via Switchable Superhydrophobic Microarrays Jau-Ye Shiu and Peilin Chen; Research Center for Applied Sciences, Academia Sinica, Taipei, Taiwan.

D4.22
Culture of Mammalian Cells on Single Crystal SiC Substrates. Camilla Coletti¹, Mark Jaroszeski², Andrew M. Hoff¹ and Stephen E. Saddow¹; ¹Electrical Engineering, University of South Florida, Tampa, Florida; ²Chemical Engineering, University of South Florida, Tampa, Florida.

D4.23
A Novel Nano Coating Technique to Increase Osteoblast Functions: Ionic Plasma Deposition Alex Reising¹, Ariel Cohen¹, Chang Yao¹, Dan Storey² and Thomas Jay Webster¹; ¹Engineering, Brown University, Providence, Rhode Island; ²Ionic Fusion, Denver, Colorado.

D4.24
The Dynamics of Cell Migration on Hyaluronic Acid Hydrogel Surface Zhi Pan¹, Kaustabh Ghosh², Xiaozheng Shu⁴, Glenn D. Prestwich⁴, Richard A. F. Clark^2,3 and Miriam Rafailovich¹; ¹Materials Science & Engineering, SUNY at Stony Brook, Stony Brook, New York; ²Biomedical Engineering, SUNY at Stony Brook, Stony Brook, New York; ³Dermatology and Medicine, SUNY at Stony Brook, Stony Brook, New York; ⁴Medicinal Chemistry, University of Utah, Salt Lake City, Utah.

D4.25
Composite Films of PLLA and PLLA/PEG Copolymer with Dual Surface Properties. Bokyung Kim, Jisook Lee, Ick Chan Kwon and Hesson Chung; Korea Institute of Science and Technology, Seoul, South Korea.

D4.26
Biocompatible Clay Langmuir Blogett Films Jaseung Koo¹, Tadanori Koga¹, Mark Schlossman², Aleksey Tikhonov³, Jonathan Sokolov¹ and Miriam H. Rafailovich¹; ¹Materials Science, State University of New York at Stony Brook, Stony Brook, New York; ²University of Illinois at Chicago, Chicago, Illinois; ³NSLS, BrookHaven National Laboratory, Upton, New York.

D4.27
Enhanced Cell Activity and Mechanical Property of Calcium Phosphate Coatings with Preferred Orientation. Hyunbin Kim¹, Renato P. Camata², Kristin M. Hennessy³, Susan L. Bellis³, Sukbin Lee⁴, Gregory S. Rohrer⁴, Anthony D. Rollett⁴ and Yogesh K. Vohra²; ¹Materials Science and Engineering, University of Alabama at Birmingham, Birmingham, Alabama; ²Physics, University of Alabama at Birmingham, Birmingham, Alabama; ³Physiology and Biophysics, University of Alabama at Birmingham, Birmingham, Alabama; ⁴Materials Science and Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania.

D4.28
Artificially Induced Ca²⁺ Flux in HCN-2 Neuronal Cells Using an Organic Electronic Ion Pump Joakim Isaksson¹, Peter Kjäll², David Nilsson³, Nathaniel D Robinson¹, Magnus Berggren¹ and Agneta Richter-Dahlfors²; ¹Dept of Science and Technology, Linkopings Universitet, Norrkoping, Sweden; ²Microbiology and Tumor Biology Center, Karolinska Institutet, Stockholm, Sweden; ³Acreo AB, Norrkoping, Sweden.

D4.29
Characterization and Quantification of the Extracellular Matrix Deposited by Embryonic Hippocampal Neurons and Dorsal Root Ganglion Neurons in a Defined, Serum-free In Vitro Culture System. Melissa Hirsch-Kuchma¹, John W Rumsey¹, Megan Murphy¹, Neelima Bhargava¹, Mainak Das¹, Mikhail Klimov², Joseph Bielitzki¹ and James J Hickman¹; ¹Nanoscience Technology Center, University of Central Florida, Orlando, Florida; ²Advanced Materials Processing and Analysis Center, University of Central Florida, Orlando, Florida.

D4.30
Scanning Force Microscopy and Fluorescent Microscopy of Microcontact Printed Antibodies and Antibody Fragments. Quynh Chu-LaGraff¹ and John LaGraff²; ¹Biology, Union College, Schenectady, New York; ²Chemistry, Siena College, Loudonville, New York.

D4.31
A Surface-Supported Bilayer Platform for Probing Membrane Protein Interactions. Kalina Hristova, Materials Science, Johns Hopkins University, Baltimore, Maryland.

D4.32
Abstract Withdrawn

D4.33
Engineered Self-Assembly of Cardiomyocytes into 3-Dimensional Muscular Thin Film Bio-composites. Adam W Feinberg¹, Alex Feigel², Sergey S Shevkoplyas², Sean P Sheehy¹, George M Whitesides² and Kevin Kit Parker¹; ¹Division of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts; ²Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts.

D4.34
Preparation of novel three-dimensional protein-based porous hydrogels Toshifumi Shiroya¹, Tatsushi Isojima¹, Hiroyuki Tanaka¹, Minako Hanasaki¹, Hisao Takeuchi¹ and Yasuo Ifuku²; ¹Functional Materials Laboratory, Mitsubishi Chemical Group Science and Technology Research Center, Inc., Yokohama, Japan; ²Research & Development, Mitsubishi Kagaku Iatron, Inc., Yachiyo, Japan.

D4.35
Silicones at the Ophthalmic Interface: Controlling Surface Roughness and (Bio)Chemistry Michael A Brook^1,2, Heather D Sheardown², Lihua Liu¹, Yang Chen¹ and Diana Morarescu²; ¹Chemistry, McMaster University, Hamilton, Ontario, Canada; ²Chemical Engineering, McMaster University, Hamilton, Ontario, Canada.

D4.36
Preferential Immobilization of Biomolecules on Self-Assembled Monolayer Template Takeo Miyake, waseda.univ, Tokyo, Japan.

D4.37
Chemical Modification of the Substrate Surface for Uniform Lipid Bilayer Formation Toshinari Isono, Hanako Tanaka and Toshio Ogino; Yokohama National University, Yokohama, Japan.

D4.38
Modified Self-assembled Monolayers for Biosensing on Waveguide Surfaces Andrew M. Dattlebaum¹, Aaron S. Anderson², Jennifer S. Martinez¹, Jurgen G. Schmidt³, W. Kevin Grace², Karen M. Grace⁴ and Basil I. Swanson²; ¹Center for Integrated Nanotechnologies, Los Alamos National Lab, Los Alamos, New Mexico; ²Chemistry Division, Los Alamos National Lab, Los Alamos, New Mexico; ³Bioscience Division, Los Alamos National Lab, Los Alamos, New Mexico; ⁴Los Alamos National Lab, Los Alamos, New Mexico.

D4.39
Self-Assembled Artificial Protein Coatings With Distinct Biofunctionality Stephen E Fischer¹, Xingyu Liu², Hai-Quan Mao^2,3 and James L Harden⁴; ¹Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland; ²Materials Science and Engineering, Johns Hopkins University, Baltimore, Maryland; ³Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland; ⁴Physics, University of Ottawa, Ottawa, Ontario, Canada.

D4.40
Targeted Drug Delivery: Effects of Grafted Polyethylene Glycol on Ligand-Receptor Binding Under Flow. Kelley Burridge^1,2 and Joyce Wong^1,2; ¹Biomedical Engineering, Boston University, Boston, Massachusetts; ²Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts.

D4.41
A Dynamical Light Scattering Study of Interactions of Oppositely Charged Proteins in Solution. Perumal Radha Ramasamy and Gary Halada; Materials Science and Engineering Department, SUNY - Stony Brook, Stony Brook, New York.

D4.42
Enzymatic Activity of Proteins Covalently Attached to Polymeric Nanoparticles. Gary Lee Thompson, Brittney Zemp, Erica Andreozzi, Rohan Satishkumar and Alexey Vertegel; Bioengineering, Clemson University, Clemson, South Carolina.

D4.43
Characterization of Structure of Synthetic Antimicrobial Peptide Anologue and Lipid Bilayer Complex. Lanfang Li and Gerard C.L. Wong; Univ. of Illinois at Urbana Champaign, Urbana, Illinois.

D4.44
First-principles Study of Adsorption Energetics of Alkanethiols on GaAs(001). Oleksandr Voznyy and Jan J. Dubowski; Department of Electrical and Computer Engineering, University of Sherbrooke, Sherbrooke, Quebec, Canada.

D4.45
Abstract Withdrawn

D4.46
Biomimetic Approach to Drug Design: Poly-L-glutamic Acid Based Polyvalent Inhibitors of Anthrax Toxin. Amit Joshi¹, Arundhati Saraph¹, Vincent Poon², Jeremy Mogridge² and Ravi S Kane¹; ¹Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, New York; ²Department of Pathobiology and Laboratory Medicine, University of Toronto, Toronto, Ontario, Canada.

D4.47
Nitrophenyl Layer Properties on Boron-doped Single Crystalline Diamond Characterized by AFM. Hiroshi Uetsuka^1,2, Dongchan Shin^1,2, Norio Tokuda¹ and Christoph E. Nebel^1,2; ¹Diamond Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan; ²New Energy and Industrial Technology development Organization (NEDO), Kawasaki, Japan.

D4.48
Fluorescent Microscopy of Adsorbed Fibrinogen on Nanocrystalline Diamond. Jacob Garguilo, Guilhem Ribeill, John Sakon, Keith Weninger and Robert Nemanich; Physics, NCSU, Raleigh, North Carolina.

D4.49
Tailoring the Pyrolytic Graphite Edge `Plane' for Binding of an O2-Reducing Enzyme. Rachel S. Heath, Christopher F. Blanford and Fraser A. Armstrong; Inorganic Chemistry, University of Oxford, Oxford, United Kingdom.

D4.50
Robust Attachment of Biomolecules to Encoded Metal Nanowires. James Sioss¹, Susan Patrick², Gary Clawson² and Christine Keating¹; ¹Penn State University, University Park, Pennsylvania; ²Hershey Medical Center, Hershey, Pennsylvania.

D4.51
Characterization of Directly Immobilized Probe DNA and Hybridized with Target DNA on Partially Functionalized Diamond Surface. Jung-Hoon Yang^1,2,3, Kwang-Soup Song^1,2,3, Shouma Kuga¹ and Hiroshi Kawarada^1,2,3; ¹Nano science and engineering, Waseda university, Tokyo, Japan; ²Nanotechnology Research Center & Institute of Biomedical Engineering, Waseda University, Tokyo, Japan; ³Consolidated Research Institute for Advanced Science and Medical Care, Waseda University, Tokyo, Japan.

D4.52
Biointerfacial Reactivity and Assembly of Gold Nanoparticles in the Presence of Amino Acids Stephanie I-Im Lim, Wui Ip, Peter Njoki and Chuan-Jian Zhong; Chemistry, State Univ. of New York at Binghamton, Binghamton, New York.

D4.53
Matrix Assisted Pulsed Laser Evaporation-Direct Write of Tissue-Engineered Materials Timothy M Patz¹, Anand Doraiswamy², Roger J Narayan² and Douglas B Chrisey³; ¹Starr-Edwards, Irvine, California; ²Biomedical Engineering, University of North Carolina, Chapel Hill, North Carolina; ³Materials Science and Engineering, Rensselaer Polytechnic Institute, Troy, New York.

SESSION D5: Surface Modification I
Chair: Jose Garrido
Tuesday Morning, November 28, 2006
Room 202 (Hynes)
8:30 AM *D5.1
Charging and Structural Transitions of Cellulose and Collagen Layers. Uwe Freudenberg¹, Sven Holger Behrens² and Carsten Werner¹; ¹Max Bergmann Center of Biomaterials, IPF, Dresden, Germany; ²BASF AG, Ludwigshafen, Germany.

9:00 AM D5.2
Electronically Switchable BioInterfaces.  J. Voros, M. Halter, C. Huwiler, T. Blattler, M. Bally, D. Grieshaber, M. Gabi.  Institute of Biomedical Engineering, ETH Zurich, Switzerland.

9:15 AM D5.3
Tailoring UV Photochemistry to Manage Polymer Surface Bioactivity Zhengmao Zhu¹, Dallas G. Hoover² and Michael J. Kelley^1,3; ¹Applied Science, Coll. of William & Mary, Newport News, Virginia; ²Animal and Food Science, U. Delaware, Newark, Delaware; ³Thomas Jefferson National Accelerator Facility, Newport News, Virginia.

9:30 AM D5.4
Abstract Withdrawn

9:45 AM D5.5
Poly(2-methyl-2-oxazoline): A Novel Nonfouling Polymer. Rupert Konradi, Bidhari Pidhatika and Marcus Textor; Dept. of Materials, LSST, ETH Zurich, Zurich, Switzerland.

10:00 AM BREAK

SESSION D6: Surface Modification II
Chair: Robert Hamers
Tuesday Morning, November 28, 2006
Room 202 (Hynes)
10:30 AM *D6.1
From Non-specific to Specific to Biospecific Surface Modifications: A Precision Control of the Biointerface Buddy D. Ratner, UWEB, University of Washington, Seattle, Washington; Department of Bioengineering, University of Washington, Seattle, Washington.

11:00 AM D6.2
The Role of Geometry and Surface Chemistry on the Stability of Supported Lipid Bilayers Morgan Mager and Nicholas Melosh; Materials Science, Stanford University, Stanford, California.

11:15 AM D6.3
Atomic Layer Deposition on Biological Macromolecules: Metal Oxide Coating of Tobacco Mosaic Virus, Ferritin and DNA Mato Knez¹, Anan Kadri², Christina Wege², Ulrich Gösele¹, Holger Jeske² and Kornelius Nielsch¹; ¹Max Planck Institute of Microstructure Physics, Halle, Germany; ²University of Stuttgart, Stuttgart, Germany.

11:30 AM D6.4
Photochemical Micro-pattern Substitution of Functional Groups for Protein Attachment Control. Masataka Murahara and Yuji Sato; Entropia Laser Initiative, Tokyo Institute of Technology, Meguro, Tokyo, Japan.

11:45 AM D6.5
Strong Resistance of Zwitterionic-Based Materials and Coatings for Biomedical and Engineering Applications. Shaoyi Jiang, Zheng Zhang and Shengfu Chen; U. of Washington, Seattle, Washington.

SESSION D7: Functional Carbon Surfaces I
Chair: Carsten Werner
Tuesday Afternoon, November 28, 2006
Room 202 (Hynes)
1:30 PM *D7.1
From Diamonds to Soot: Carbon as a Versatile Platform for Biomaterials Integration Robert J Hamers, Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin.

2:00 PM D7.2
Surface Wettability of Nanostructured Carbon Materials- From Superhydrophobicity to Superhydrophilicity Xingcheng Xiao¹, Brian Sheldon¹, Janet Rankin¹, Aihui Yan¹, Robert Hurt¹, Sirinrath Sirivisoot¹, Thomas Webster¹, Erkan Konca¹, Orlando Auciello² and John A. Carlisle²; ¹Engineering Division, Brown University, Providence, Rhode Island; ²Materials Science Division, Argonne National Laboratory, Argonne, Illinois.

2:15 PM D7.3
Engineered Carbon Surfaces for Enzymatic Bio-fuel Cells. Christopher F. Blanford, Rachel S. Heath and Fraser A. Armstrong; University of Oxford, Oxford, United Kingdom.

2:30 PM D7.4
Diamond Surfaces: A Novel Platform for Biosensors. Jose Garrido, Andreas Haertl, Simon Lud and Martin Stutzmann; Walter Schottky Institut, Technische Universitat Munchen, Garching, Germany.

2:45 PM D7.5
Abstract Withdrawn

3:00 PM BREAK

SESSION D8: Functional Carbon Surfaces II
ChairS: Orlando Auciello and Jose A. Garrido
Tuesday Afternoon, November 28, 2006
Room 202 (Hynes)
3:30 PM *D8.1
DLC Coatings in Medical Applications Roland Hauert, Nanoscale Materials Science, EMPA, Dübendorf, Switzerland.

4:00 PM D8.2
Antibacterial Silver-containing DLC and ta-C coatings: A Comparative Study. Jose Luis Endrino^1,2, Matthew Allen³, Ramon Escobar Galindo², Jose Maria Albella² and Andre Anders¹; ¹Lawrence Berkeley National Laboratory, Berkeley, California; ²Instituto de Ciencias de Materiales de Madrid, Madrid, Spain; ³SUNY Upstate Medical University, Syracuse, New York.

4:15 PM D8.3
Study of Ultrananocrystalline Diamond Films as Implantable Biomedical Devices: Assessment of their Biocompatibility to Cell Attachment and Growth Bing Shi¹, Qiaoling Jin², Liaohai Chen² and Orlando Auciello^1,3; ¹Materials Science Division, Argonne National Laboratory, Argonne, Illinois; ²Biosciences Division, Argonne National Laboratory, Argonne, Illinois; ³Center for Nanoscale Materials, Argonne National Laboratory, Argonne, Illinois.

4:30 PM D8.4
Large-Scale Carbon Nanotube Patterns for Directed Growth of Mesenchymal Stem Cells Sung Young Park¹, Kyu-Back Lee², Yongdoo Park² and Seunghun Hong¹; ¹Physics and NANO Systems Institute, Seoul National University, Seoul, South Korea; ²Dept. of Biomedical Engineering, College of Medicine, Korea University, Seoul, South Korea.

4:45 PM D8.5
Mesoporous Carbide-derived Carbons with Porosity Tuned for Efficient Adsorption of Cytokines. Gleb Yushin¹, Elizabeth N Hoffman¹, Michel W Barsoum¹, Yury Gogotsi¹, Carol A Howell², Susan R Sandeman², Gary J Phillips², Andrew W Lloyd² and Sergey V Mikhalovsky²; ¹Materials Science and Engineering, A.J. Drexel Nanotechnology Institute, Drexel University, Philadelphia, Pennsylvania; ²School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, Moulsecoomb, United Kingdom.

SESSION D9: Advances in Tissue Engineering
Chairs: Erika Johnston and Anne Meyer
Wednesday Morning, November 29, 2006
Room 202 (Hynes)
8:30 AM *D9.1
Membrane Solutions Enabling Channel Protein-based Sensing. Noah Malmstadt, Tae-Joon Jeon and Jacob Schmidt; Bioengineering, UCLA, Los Angeles, California.

9:00 AM D9.2
Development of Multifunctional Photocurable Degradable Elastomers Christiaan Nijst, Jeffrey M Karp, Joost P Bruggeman, Lino Ferreira, Andreas Zumbuehl, Christopher Bettinger and Robert Langer; Massachusetts Institute of Technology, Cambridge, Massachusetts.

9:15 AM D9.3
DNA Hydrogels Soong Ho Um, Nokyoung Park and Dan Luo; Biological and Environmental Engineering, Cornell University, Ithaca, New York.

9:30 AM D9.4
Synthetic ECM Differentially Modulates the Growth of Stem Cells and Preosteoblasts. Susan X. Hsiong^1,2, Paolo Carampin¹, Hyun-Joon Kong¹ and David J. Mooney¹; ¹DEAS, Harvard University, Cambridge, Massachusetts; ²Chemical Engineering, University of Michigan, Ann Arbor, Michigan.

9:45 AM D9.5
Biochemical Surface Modifications of Collagen-GAG Membranes Direct Keratinocyte Function. Katie Ann Bush^1,2, Brett Downing^1,2, Ernesto Soto³, W. Grant McGimpsey³, Mehmet Toner^4,5,6 and George Pins¹; ¹Biomedical Engineering, Worcester Polytechnic Institute, Worcester, Massachusetts; ²Graduate School of Biomedical Sciences, University of Massachusetts, Worcester, Massachusetts; ³Chemistry & Biochemistry, Worcester Polytechnic Institute, Worcester, Massachusetts; ⁴Center for Engineering in Medicine/Surgical Services, Massachusetts General Hospital, Boston, Massachusetts; ⁵Shriners Burns Hospital, Boston, Massachusetts; ⁶Harvard Medical School, Boston, Massachusetts.

10:00 AM BREAK

10:30 AM *D9.6
Matrix Manipulation of Growth Factor Signaling to Enhance Regenerative Cell Behaviors. Linda G. Griffith, Professor of Biological Engineering and Mechanical Engineering, MIT, Cambridge, Massachusetts.

11:00 AM D9.7
Preparation of Hydroxyapatite Sheet with Various Shapes and its Application to Programmable Tissue Engineering Scaffold. Hiroaki Nishikawa^1,2,3, Ryouta Hatanaka^1,2, Masanobu Kusunoki^1,2,3 and Shigeki Hontsu^1,2,3; ¹B.O.S.T., Kinki Univ., Kinokawa, Wakayama, Japan; ²CREST-JST, Tokyo, Japan; ³Wakayama Pref. C.R.E.A.T.E. of the JST, Wakayama, Japan.

11:15 AM D9.8
Synthesis of a Novel Electrically Conducting, Biocompatible, Biodegradable Polymer for Biomedical Applications. Nathalie K. Guimard¹, Jonathan L. Sessler¹ and Christine E. Schmidt²; ¹Chemistry, University of Texas at Austin, Austin, Texas; ²Biomedical Engineering, University of Texas at Austin, Austin, Texas.

11:30 AM D9.9
Three-dimensional Control of Biospecificity via Two-photon Engineered Polymer Scaffolds Prakriti Tayalia¹, Tommaso Baldacchini¹, Cleber Renato Mendonca^1,3, David J Mooney¹ and Eric Mazur^1,2; ¹Division of Engineering & Applied Sciences, Harvard University, Cambridge, Massachusetts; ²Department of Physics, Harvard University, Cambridge, Massachusetts; ³Instituto de Física de São Carlos, Universidade de São Paulo, São Carlos, SP, Brazil.

11:45 AM D9.10
Novel Microfabrication Methods and Materials for Producing 3D Physically and Chemically Structured Polymeric Tissue Engineering Scaffolds Benita M. Comeau and Clifford Lee Henderson; School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia.

SESSION D10: Bone and Biomineral Interfaces
Chairs: Erika Johnston and Jacob Schmidt
Wednesday Afternoon, November 29, 2006
Room 202 (Hynes)
1:30 PM *D10.1
Aspects of Biosurface Friction and Lubrication Anne E. Meyer, Industry/University Center for Biosurfaces, University at Buffalo, Buffalo, New York.

2:00 PM D10.2
Hydroxyapatite-peptide Based Composite Hydrogels for Bone Regeneration. Hassna Rehman Ramay^1,2, Darrin J Pochan^1,2 and Joel P Schneider³; ¹Materials Science and Engineering, University of Delaware, Newark, Delaware; ²Delaware Biotechnology Institute, University of Delaware, Newark, Delaware; ³Chemistry and Biochemistry, University of Delaware, Newark, Delaware.

2:15 PM D10.3
Polymer/Ceramic Nanocomposite Tissue Engineering Scaffolds for More Effective Orthopedic Applications. Huinan Liu and Thomas J Webster; Division of Engineering, Brown University, Providence, Rhode Island.

2:30 PM D10.4
Bone Formation Mediated by Growth Factors Embedded in a Polyelectrolyte Multilayer Film. Erell Le guen¹, Andree Dierich², Pierre Schaaf³, Jean-Claude Voegel¹ and Nadia Jessel¹; ¹UMR 595, Biomaterials, INSERM, Strasbourg, France; ²IGBMC, ICS, CNRS/ULP, Strasbourg, France; ³Institut Charles Sadron, CNRS/ULP, Strasbourg, France.

2:45 PM BREAK

3:15 PM *D10.5
Interface Tissue Engineering for Soft and Hard Tissue Integration. Helen Lu, J. P. Spalazzi, K. L. Moffat and I. E. Wang; Biomedical Engineering, Columbia University, New York, New York.

3:45 PM D10.6
Carbon Nanotube-Reinforced Hydroxyapatite Nanocomposites. Ashley Ann White¹, Osa Emohare², Roger Brooks², Neil Rushton², Ian Kinloch¹ and Serena Best¹; ¹Dept. of Materials Science & Metallurgy, University of Cambridge, Cambridge, United Kingdom; ²Orthopaedic Research Unit, University of Cambridge, Cambridge, United Kingdom.

4:00 PM D10.7
Laser Direct Writing of Bioceramics for Tissue Engineering Lance M Harris¹, Anand Doraiswamy², Roger J Narayan², S. B Qadri¹, R. Modi¹ and Douglas B Chrisey^1,3; ¹United States Naval Research Laboratory, Washington, District of Columbia; ²Biomedical Engineering, University of North Carolina, Chapel Hill, North Carolina; ³Department of Materials Science and Engineering, Rensselaer Polytechnic Institute, Washington, New York.

4:15 PM D10.8
Patterning Inorganic Films by Templating Colloids of an Amorphous Mineral Precursor Yi-Yeoun Kim and Laurie B, Gower; Materials Science & Engineering, University of Florida, Gainesville, Florida.

4:30 PM D10.9
Effect of Substrate Surface Modification on Biomineralization of Osteoblasts. Yizhi Meng¹, Xiaolan Ba², Seo-Young Kwak³, Elaine DiMasi³, Jiji Gu⁴, Milan Kahanda⁵, Vladimir Zaitsev², Shouren Ge², Nadine Pernodet², Miriam Rafailovich² and Yi-Xian Qin¹; ¹Biomedical Engineering, Stony Brook University, Stony Brook, New York; ²Materials Science and Engineering, Stony Brook University, Stony Brook, New York; ³National Synchrotron Light Source, Brookhaven National Laboratory, Upton, New York; ⁴Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts; ⁵Ward Melville High School, East Setauket, New York.

4:45 PM D10.10
Nano to Micro Scale Porous Silicon as a Cell Interface for Bone Tissue Engineering. Wei Sun¹, Tzong-Jen Sheu², Edward Puzas^2,1 and Philippe M. Fauchet^3,1; ¹Biomedical Engineering, University of Rochester, Rochester, New York; ²Orthopaedics, University of Rochester, Rochester, New York; ³Electrical and Computer Engineering, University of Rochester, Rochester, New York.

SESSION D11: Molecular Bioelectronics
Chair: Janos Voros
Thursday Morning, November 30, 2006
Room 202 (Hynes)
8:30 AM *D11.1
Electric Field Induced Attachment of Proteins Monitored by Surface Plasmon Resonance David R. McKenzie, Richard Morrow and Marcela M. Bilek; School of Physics, University of Sydney, Sydney, New South Wales, Australia.

9:00 AM D11.2
Reconstitution of Protein for Bioelectronic Applications Jae-Woo Kim¹, Sang H. Choi², Peter T. Lillehei², Sang-Hyon Chu¹ and Glen C. King²; ¹National Institute of Aerospace, Hampton, Virginia; ²NASA LaRC, Hampton, Virginia.

9:15 AM D11.3
Optically Induced Changes in the Electrical Properties of the Protein - Porphyrin Complexes. Maxim P. Nikiforov¹, Bohdana Discher² and Dawn Bonnell¹; ¹MSE, University of Pennsylvania, Philadlephia, Pennsylvania; ²Dept of Biochemistry&Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania.

9:30 AM D11.4
Dynamic Control of Biomolecular Activity Using Nanoscale Electrical Interfaces Ian Y Wong and Nicholas A Melosh; Materials Science and Engineering, Stanford University, Stanford, California.

9:45 AM BREAK

SESSION D12: Bioelectronics and Biomedical Tools
Chair: Janos Voros
Thursday Morning, November 30, 2006
Room 202 (Hynes)
10:15 AM *D12.1
Micro-structured Platinum Electrodes for a Retinal Prosthesis. Brian Mech, Robert J Greenberg and David M Zhou; Second Sight Medical Products, Sylmar, California.

10:45 AM D12.2
Optical Micro-resonator Probes for Cortical Recording. Jiayi Zhang¹, Yoon-Kyu Song², John P Donoghue³ and Arto V Nurmikko^2,1; ¹Physics Department, Brown University, Providence, Rhode Island; ²Division of Engineering, Brown University, Providence, Rhode Island; ³Neuroscience Department, Brown University, Providence, Rhode Island.

11:00 AM D12.3
An Electronically Controlled Release Platform for Studying Cell Behavior Elizabeth A Hager-Barnard, Jules J. VanDersarl, Erhan Yenilmez and Nicholas A. Melosh; Materials Science and Engineering, Stanford University, Stanford, California.

11:15 AM D12.4
Imaging Electromechanical Coupling of a Protein Membrane in Solution with an Electrically Biased Tip. Brian J Rodriguez¹, Stephen Jesse¹, Sergei V Kalinin¹, Sophia Hohlbauch², Irene Revenko² and Roger Proksch²; ¹Materials Science and Technology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee; ²Asylum Research, Santa Barbara, California.

11:30 AM D12.5
Inkjet Printing of Biocompatible Adhesives: Surgical Adhesives, Wound Closures and Anti-fouling in Medical Devices Anand Doraiswamy, Peter L Mente and Roger J Narayan; Joint Dept. of Biomedical Engineering, University of North Carolina, Chapel Hill, North Carolina.

SESSION D13: Nanopatterning
Chair: Andreas Offenhausser
Thursday Afternoon, November 30, 2006
Room 202 (Hynes)
1:30 PM *D13.1
Integration of Biomolecules with Inorganic Framework Materials: Novel Approaches to Protein-Based Nanoscale Devices Millicent Anne Firestone^1,2, Brian Reiss^1,2, Orlando Auciello^1,2, Leonidas E. E. Ocola² and Deborah K. Hanson³; ¹Materials Science Division, Argonne National Laboratory, Argonne, Illinois; ²Center for Nanoscale Materials, Argonne National Laboratory, Argonne, Illinois; ³Biosciences Division, Argonne National Laboratory, Argonne, Illinois.

2:00 PM D13.2
Surface Patterning Proteins and Protein-conjugated Nanoparticles in Immobilized or Lipid-membrane-supported Arrays: Using Engineered Cell-surface Contacts to Model Complex Cell-cell Interactions. Darrell J. Irvine¹ and Junsang Doh²; ¹Mat. Sci. & Eng./Biological Eng., MIT, Cambridge, Massachusetts; ²Chemical Eng., MIT, Cambridge, Massachusetts.

2:15 PM D13.3
Directed Self-assembly of Virus Particles at Chemical Templates. James J. DeYoreo¹, Sung-Wook Chung¹, Chin Li Cheung¹, Selim Elhadj¹, Anju Chatterji², Tianwei Lin², John E Johnson², Chung-Yi Chiang³, Angela M Belcher³, Andrew Presley⁴ and Matthew B Francis⁴; ¹Lawrence Livermore National Laboratory, Livermore, California; ²The Scripps Research Institute, La Jolla, California; ³Massachusetts Institute of Technology, Cambridge, Massachusetts; ⁴University of California at Berkeley, Berkeley, California.

2:30 PM D13.4
S-layers as Templates in the Formation of Two-dimensional Nanoscale Patterns. Dietmar Pum and Uwe B. Sleytr; Center for Nanobiotechnology, University of Natural Resources and Applied Life Sciences, Vienna, Austria.

2:45 PM D13.5
Protein Orientation and Conformation Controlled by Charged Self-Assembled Monolayers on Nano-patterned Au Discs and Holes. Qiuming Yu^1,2, Dong Qin^1,2 and Greg Golden^1,2; ¹Center for Nanotechnology, University of Washington, Seattle, Washington; ²Department of Bioengineering, University of Washignton, Seattle, Washington.

3:00 PM BREAK

SESSION D14: Nanobioelectronics
Chair: Millicent Firestone
Thursday Afternoon, November 30, 2006
Room 202 (Hynes)
3:30 PM *D14.1
DNA, Proteins, and Neurons Coupled to Electronic Devices. Andreas Offenhausser, Forschungszentrum Juelich, Juelich, Germany.

4:00 PM D14.2
Selective Biofunctionalization of Silicon Nanowires on SiO₂ Surfaces Ansoon Kim, Chil Seong Ah, Han Young Yu, In Bok Baek, Jong-Heon Yang, Chang-Geun Ahn and Seong Jae Lee; IT Convergence & Components Lab., Electronics and Telecommunications Research Institute, Daejeon, South Korea.

4:15 PM D14.3
3-D Conformal Electrode Arrays for Interfacing with Topologically Complex Neural Surfaces. Karlene Rosera Maskaly, John S. George, Craig A. Chavez and James L. Maxwell; Los Alamos National Laboratory, Los Alamos, New Mexico.

4:30 PM D14.4
Designing and Implementing High Density Nanowire Arrays for Detection, Stimulation, and Inhibition of Neuronal Signals Brian P. Timko¹, Fernando Patolsky¹, Guihua Yu¹, Ying Fang¹, Andrew B. Greytak² and Charles M. Lieber^1,3; ¹Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts; ²Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts; ³Division of Engineering and Applied Science, Harvard University, Cambridge, Massachusetts.

4:45 PM D14.5
Study of Polymeric Microneedle Arrays for Drug Delivery. Aleksandr Ovsianikov¹, Roger Narayan², Anand Doraiswamy², Peter Mente², Prasad Mageswaran² and Boris Chichkov¹; ¹Nanotechnology Department, Laser Zentrum Hannover e.V., Hannover, Germany; ²Joint Department of Biomedical Engineering, University of North Carolina, Chapel Hill, North Carolina.

SESSION D15: Poster Session
Thursday Evening, November 30, 2006
8:00 PM
Exhibition Hall D (Hynes)
D15.1
Abstract Withdrawn

D15.2
Dental Prostheses with Anti-Fungus Surface Layer Based on Segmented Polyurethane. Erkesh Batyrbekov, Rinat Iskakov and Bulat Zhubanov; Institute of Chemical Sciences, Almaty, Kazakhstan.

D15.3
Biomineralization Induced by Self-assembled Proteins and Extracellular Protein Matrix of Osteoblasts. Xiaolan Ba¹, Yi-zhi Meng², Seo Young Kwak³, Elaine DiMasi³, Shou-ren Ge¹, Vladimir Zaitsev¹, Yi-xian Qin², Nadine Pernodet¹ and Miriam Rafailovich¹; ¹Materials Science and Engineering, SUNY-Stony Brook, Stony Brook, New York; ²Biomedical Engineering, Stony Brook University, Stony Brook, New York; ³National Synchrotron Light Source, Brookhaven National Laboratory, Upton, New York.

D15.4
Developing Biosensors for Monitoring Orthopedic Tissue Growth Sirinrath Sirivisoot, Chang Yao, Xingcheng Xiao, Brian Sheldon and Thomas Webster; Engineering, Brown University, Providence, Rhode Island.

D15.5
In vitro Evaluation of Macrophage Activity on Nanophase Ceramics. Peishan Liu-Snyder and Thomas Webster; Brown University, Providence, Rhode Island.

D15.6
Evaluation of Biological Responses of UMR-106 Cells to Porous PHBV Matrix Coated with Collagen. Hui Liu¹, John Stubbs² and Dharmaraj Raghavan¹; ¹Chemistry, Howard University, Washington, DC, District of Columbia; ²Microbiology, College of Medicine, Howard University, Washington, District of Columbia.

D15.7
The Growth of CdS Films under Aqueous Conditions using a Biomimetic Approach. Sang Soo Jee¹, Yi-yeoun Kim² and Laurie Gower¹; ¹Materials Science and Engineering, University of Florida, Gainesville, Florida; ²Specialty Minerals Inc., Bethlehem, Pennsylvania.

D15.8
Development of Novel Nano-structured Tissue Engineering Scaffold Materials through Self-assembly for Bed-side Orthopedic Applications. Lijie Zhang¹, Hicham Fenniri² and Thomas J. Webster¹; ¹Divisions of Engineering and Orthopedics, Brown University, Providence, Rhode Island; ²National Institute for Nanotechnology and Department of Chemistry, National Research Council and the University of Alberta, Edmonton, Alberta, Canada.

D15.9
Dual-Syringe Reactive Electrospinning of Cross-linked Hyaluronic Acid Hydrogel Nanofibers for Tissue Engineering Applications Yuan Ji¹, Kaustabh Ghosh², Bingquan Li¹, Jonathan Sokolov¹, Richard Clark² and Miriam Rafailovich¹; ¹Materials Science and Engineering, SUNY at Stony Brook, Stony Brook, New York; ²Department of Biomedical Engineering, SUNY at Stony Brook, Stony Brook, New York.

D15.10
Nonfouling and Responsive Zwitterionic Hydrogels with Immobilized Proteins and Improved Mechanical Strength. Shaoyi Jiang, Zheng Zhang and Shengfu Chen; U. of Washington, Seattle, Washington.

D15.11
Molecular Origins of the Protein-Resistant Properties of Methyl 1-(3-Mercaptopropyl) Penta(Ethylene Oxide) Self-Assembled Monolayers. Jae Hyeok Choi¹, Hailemariam Negussie², Sarah S Ng³, David J. Vanderah⁴ and Ortiz Christine³; ¹Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts; ²Department of Biomedical Engineering, Boston University, Boston, Massachusetts; ³Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts; ⁴Biochemical Sciences Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, Maryland.

D15.12
Finite Element Analysis of Microjoint Bond Degradation in Cerebrospinal Fluid. Jesse Law and Ahsan Mian; Mechanical and Industrial Engineering, Montana State University, Bozeman, Montana.

D15.13
Fabrication of Nano-patterned Surfaces for Bio-sensing Devices by Colloidal Lithography. Andrea Valsesia, Pascal Colpo, Patricia Lisboa, Frederic Bretagnol, Giacomo Ceccone and Francois Rossi; EC-JRC-IHCP, Ispra, Varese, Italy.

D15.14
Site-Specific Patterning of Biomaterials on PECVD Generated Surfaces Jeffrey Stephen Zabinski, Joseph M. Slocik, Eric R. Beckel, Hao Jiang, Jesse O. Enlow, Timothy J. Bunning and Rajesh R. Naik; Air Force Research Lab, Wright-Patterson AFB, Ohio.

D15.15
Photolithographic Process, Based on High Contrast Acrylate Photoresist, for Multi -Protein Patterning. Margarita Chatzichristidi¹, Panagiota S. Petrou², Antonios M. Douvas¹, Constantinos D. Diakoumakos¹, Ioannis Raptis¹, Konstantinos Misiakos¹, Sotiris E. Kakabakos² and Panagiotis Argitis¹; ¹Inst. of Microelectronics, NCSR "Demokritos", Athens, Greece; ²Inst. of Radioisotopes & Radiodiagnostic Products, NCSR "Demokritos", Athens, Greece.

D15.16
Abstract Withdrawn

D15.17
Far-Field Arrangement of Proteins in a Zero-mode Waveguide for Single Molecule Imaging Takashi Tanii¹, Hironori Sonobe¹, Rena Akahori¹, Takeo Miyake¹, Taro Ueno², Takashi Funatsu², Naonobu Shimamoto¹ and Iwao Ohdomari¹; ¹School of Sci. & Eng., Waseda University, Tokyo, Japan; ²Graduate School of Parmaceutical Sciences, The University of Tokyo, Tokyo, Japan.

D15.18
Local Electron Beam Induced Reduction and Crystallization in Electrochemically Deposited Amorphous TiO2 Films Philippe Kern and Johann Michler; EMPA, Thun, Switzerland.

D15.19
Control of Enzymatic Activities by Fe3O4 Nanoparticles Hui Zhou¹, Marie-Eve Aubin-Tam² and Kimberly Hamad-Schifferli^3,2; ¹Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts; ²Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts; ³Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts.

D15.20
Increased Osteoblast Adhesion on Nanograined Hydroxyapatite/Calcium Titanate and Tricalcium Phosphate/Calcium Titanate Composites Huinan Liu¹, Celaletdin Ergun², John W Halloran³ and Thomas J Webster¹; ¹Division of Engineering, Brown University, Providence, Rhode Island; ²Mechanical Engineering Department, Istanbul Technical University, Istanbul, Turkey; ³Materials Science and Engineering, University of Michigan, Ann Arbor, Michigan.

D15.21
Patterned Polymer Brushes for Directed Ionic and Molecular Transport Rachel C Evans^1,2,3, Huilin Tu^1,2,3 and Paul V Braun^1,2,3; ¹Materials Science and Engineering, University of Illinois Urbana-Champaign, Urbana, Illinois; ²Fredrick Seitz Materials Research Laboratory, Urbana, Illinois; ³Beckman Institute for Advanced Science and Technology, Urbana, Illinois.

D15.22
Reusable, Reversibly Sealable Parylene-C Membranes for Cell and Protein Patterning. Bimalraj Rajalingam^1,2, Dylan Wright³, Jeffrey M Karp³, Selvapraba Selvarasah⁴, Yibo Ling^2,5, Judy Yeh⁶, Robert Langer^2,3,6, Mehmet R Dokmeci⁴ and Ali Khademhosseini^2,1; ¹Department of Medicine, Brigham and Women's Hospital,Harvard Medical School, Boston, Massachusetts; ²Harvard-MIT Division of Health Science and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts; ³Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts; ⁴Electrical and Computer Engineering Department,Center for High Rate Nanomanufacturing, Northeastern University, Boston, Massachusetts; ⁵Department of Electrical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts; ⁶Division of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts.

D15.23
Micro and Nano-structured Bioactive Interfaces using Piezoelectric Ink Jet Technology Anand Doraiswamy¹, Jan Sumerel², Cerasela Dinu³, Joe Howard³, Douglas B Chrisey⁴ and Roger J Narayan¹; ¹Biomedical Engineering, University of North Carolina, Chapel Hill, North Carolina; ²Dimatix Inc., Santa Clara, California; ³Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany; ⁴Materials Science and Engineering, Rensselaer Polytechnic Institute, Troy, New York.

D15.24
Micropatterned Parylene Stencils for Generation of Dynamic and Static Patterned Cellular Co-cultures. Dylan Wright¹, Bimalraj Rajalingam^2,3, Selvapraba Selvarasah⁴, Yibo Ling^3,5, Mehmet R Dokmeci⁴ and Ali Khademhosseini^2,3; ¹Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts; ²Department of Medicine, Brigham and Women's Hospital,Harvard Medical School, Boston, Massachusetts; ³Harvard-MIT Division of Health Science and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts; ⁴Electrical and Computer Engineering Department,Center for High Rate Nanomanufacturing, Northeastern University, Boston, Massachusetts; ⁵Department of Electrical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts.

D15.25
Modeling Block Copolymer Interactions with Biomimetic Membranes Shashishekar P Adiga, Peter Zapol and Millicent A. Firestone; Materials Science Division, Argonne National Laboratory, Argonne, Illinois.

D15.26
Agarose Microfluidics Devices for Diagnostics and Tissue Engineering. Yibo Ling^1,2, Jamie Rubin³, Jeffrey M Karp³ and Ali Khademhosseini^1,4; ¹Harvard-MIT Division of Health Science and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts; ²Department of Electrical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts; ³Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts; ⁴Department of Medicine, Brigham and Women's Hospital,Harvard Medical School, Boston, Massachusetts.

D15.27
Atomic Structure and Bonding of Water Overlayer on Cu(110): the Borderline for Intact and Dissociative Adsorption. Jun Ren¹ and Sheng Meng²; ¹Department of Physics, Sichuan Normal University, Chengdu, China; ²Physics Department, Harvard University, Cambridge, Massachusetts.

D15.28
Preparation and Characterization of a Superparamagnetic Polymer Nanocomposite Nicole Brenner^1,2, Rebecca Isseroff², Richard Gambino¹, Shian Liang¹, D. Sunil³, Mayu Si¹, Lourdes Collazo¹, Nadine Pernodet¹ and Miriam Rafailovich¹; ¹Materials Science & Engineering, Stony Brook University, Stony Brook, New York; ²Lawrence High School, Cedarhurst, New York; ³Queens college, Queens, New York.

D15.29
Label-free Biological Microarray Imaging Using Spectral Reflectivity Information. Emre Ismail Ozkumur¹, Julia Rentz Dupuis¹, David Alan Bergstein¹, Rostem Irani², Michael Ruane¹, Bennett Goldberg³ and Selim Unlu¹; ¹Electrical and Computer Engineering, Boston University, Boston, Massachusetts; ²Center for Advanced Genomic Technology, Boston University, Boston, Massachusetts; ³Physics, Boston University, Boston, Massachusetts.

D15.30
Abstract Withdrawn

D15.31
Quantum Chemical Study of TiO2/Dopamine-DNA Triads. Peter Zapol^1,2, Manuel Vega-Arroyo², Larry A Curtiss^1,2 and Tijana Rajh²; ¹Materials Science Division, Argonne National Laboratory, Argonne, Illinois; ²Chemistry Division, Argonne National Laboratory, Argonne, Illinois.

D15.32
Detection of the Enzyme Glucose Oxidase Immobilized on Si-based Surfaces Sebania Libertino¹, Manuela Fichera¹, Patrick Fiorenza¹, Corrado Bongiorno¹ and Antonino Scandurra²; ¹Catania, CNR - IMM, Catania, Italy; ²SUPERLAB, Consorzio Catania Ricerche, Catania, Italy.

D15.33
Detection of Respiratory Viruses with Plastic High Throughput Screening Devices Zhengshan Zhao², Gerardo Antonio Diaz-Quijada¹, Regis Peytavi², Éric LeBlanc², Johanne Frenette², Guy Boivin², Jim V. Zoval³, Marc J. Madou³, Michel M. Dumoulin¹, Teodor Veres¹ and Michel G. Bergeron²; ¹Industrial Materials Institute, National Research Council, Boucherville, Quebec, Canada; ²Centre de recherche en infectiologie, Université Laval, Sainte Foy, Quebec, Canada; ³Department of Mechanical and Aerospace Engineering, University of California, Irvine, California.

D15.34
DNA-Mediated Assembly and Disassembly of Micron-Sized Particles Chris Tison and Valeria Milam; Georgia Institute of Technology, Atlanta, Georgia.

D15.35
Efficiency of Gold DNA Conjugates for Antisense Gene Silencing. Katherine Alice Brown and Kimberly Hamad-Schifferli; Biological Engineering, MIT, Cambridge, Massachusetts.

D15.36
Multiscale Modeling of DNA Translocation through a Nanopore. Maria Fyta¹, Simone Melchionna², Efthimios Kaxiras¹ and Sauro Succi³; ¹Department of Physics and Division of Engineering and Applied Sciences, Harvard Univeristy, Cambridge, Massachusetts; ²INFM-SOFT, Department of Physics, Universita di Roma 'La Sapienza', Rome, Italy; ³Istituto Applicazioni Calcolo, CNR, Rome, Italy.

D15.37
Titania Nanoscrolls for Drug Delivery. Harsha Prabhakar Kulkarni¹ and Yue Wu^1,2; ¹Curriculum in Applied and Material Science, University Of North Carolina at Chapel Hill, Chapel Hill, North Carolina; ²Department Of Physics and Astronomy, University Of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

D15.38
Polyelectrolyte assemblies as multicompartment films for embedding drugs Philippe Lavalle¹, Juan Mendez Garza¹, Erell Le Guen¹, Nadia Jessel¹, Pierre Schaaf² and Jean-Claude Voegel¹; ¹Biomaterials, INSERM, Strasbourg, France; ²Institut Charles Sadron, CNRS, Strasbourg, France.

D15.39
The Design of Potent Liposome-Based Inhibitors of Anthrax Toxin. Prakash Rai¹, Chakradhar Padala¹, Vincent Poon², Arundhati Saraph¹, Saleem Basha¹, Sandesh Kate¹, Kevin Tao², Jeremy Mogridge² and Ravi Kane¹; ¹Rensselaer Polytechnic Institute, Troy, New York; ²University of Toronto, Toronto, Ontario, Canada.

D15.40
Abstract Withdrawn

D15.41
Formation of DMPC Bilayers on Polyelectrolyte Multilayers Studied by Neutron Reflectometry Rumen Krastev, Christophe Delajon, Narayan Chandra Mishra and Helmuth Möhwald; Interfaces, Max-Planck Institute of Colloids and Interfaces, Potsdam, Germany.

D15.42
On-dependent s-SNOM on Porphyrin Monolayers. Maxim P. Nikiforov¹, Susanne Schneider², Ulrich Zerweck², Christian Loppacher², Stefan Grafstroem², Tae-Hong Park³, Michael Therien³, Lukas Eng³ and Dawn Bonnell¹; ¹MSE, University of Pennsylvania, Philadlephia, Pennsylvania; ²Institute of applied photophysics, Dresden, D-01062, Germany; ³Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania.

SESSION D16: DNA, Lipids and Drug Delivery I
Chair: Martin Eickhoff
Friday Morning, December 1, 2006
Room 202 (Hynes)
8:30 AM *D16.1
Lipid Bilayers and Vesicles at Surfaces; Basic Mechanisms and Applications. Angelica Wikstrom, Dorota Thid, Indriati Pfeiffer, Bastien Seantier, Sofia Svedhem, Sarunas Petronis, Michael Zaech, Julie Gold and Bengt Kasemo; Applied Physics, Chalmers University of Technology, Gothenburg, Sweden.

9:00 AM D16.2
Self-Assembling Systems of Amphiphilic Polymers as Skin Permeation Enhancing Carriers for Topical Delivery Junoh Kim^1,2, Jongwon Shim¹, Ju Hee Ryu¹, Yong-Jin Kim¹, Ih-Seop Chang¹ and Kookheon Char²; ¹Nanotechnology Research Team, AMOREPACIFIC Corporation R&D Center, Yongin-Si, Gyeonggi-Do, South Korea; ²School of Chemical and Biological Engineering, Seoul National University, Seoul, South Korea.

9:15 AM D16.3
Layer-by-layer Polymer Thin Films for Sequential Drug Delivery. Helen F Chuang and Paula T Hammond; Chemical Engineering, MIT, Cambridge, Massachusetts.

9:30 AM D16.4
Utilizing the Micromechanical Properties of DNA for Controlled Nanoparticle Assembly Mathew M. Maye¹, Dmytro Nykypanchuk¹, Daniel van der Lelie² and Oleg Gang¹; ¹Center for Functional Nanomaterials, Brookhaven National Laboratory, Upton, New York; ²Biology Department, Brookhaven National Laboratory, Upton, New York.

9:45 AM D16.5
Self-recognising Fluid Monolayers of DNA-based Surfactants: Properties and Applications Vesselin N. Paunov, Chun Xu, Pietro Taylor and Paul D.I. Fletcher; Department of Chemistry, University of Hull, Hull, North Humberside, United Kingdom.

10:00 AM BREAK

SESSION D17: DNA, Lipids and Drug Delivery II
Chair: Martin Eickhoff
Friday Morning, December 1, 2006
Room 202 (Hynes)
10:30 AM D17.1
Molecular Dynamics Study of Peptide Nucleic Acid Affinity to Lipid Bilayer. Pawel Weronski^1,2, Yi Jiang¹ and Steen Rasmussen³; ¹Theoretical Division, Los Alamos National Laboratory, Los Alamos, New Mexico; ²Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Krakow, Poland; ³Earth and Environmental Sciences Division, Los Alamos National Laboratory, Los Alamos, New Mexico.

10:45 AM D17.2
Novel Bioactive Enzyme/DNA/Inorganic Nanomaterials. Akhilesh Bhambhani and Challa V. Kumar; Department of Chemistry, University of Connecticut, Storrs, Connecticut.

11:00 AM D17.3
Tracking the Pathway of Inorganic Particles in Living Cells. Viktoriya Sokolova¹, Anna Kovtun¹, Rolf Heumann² and Matthias Epple¹; ¹Institute of Inorganic Chemistry, University of Duisburg-Essen, Essen, Germany; ²Chair of Biochemistry, Molecular Neurobiochemistry, University of Bochum, Bochum, Germany.

11:15 AM D17.4
Optical and Magnetic Mismatch Detection of Controlled DNA Assemblies onto Au Patterned SiO₂ Devices. Steven Hira^1,2, P. Manandhar², P. Xiong², P. B. Chase², S. von Molnár² and G. Strouse^1,2; ¹Chemistry and Biochemistry, Florida State University, Tallahassee, Florida; ²Center for Materials Research and Technology (MARTECH), Florida State University, Tallahassee, Florida.

11:30 AM D17.5
A Cell-free Protein Producing DNA Hydrogel Nokyoung Park, Soong Ho Um and Dan Luo; Biological and Environmental Engineering, Cornell University, Ithaca, New York.