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Symposium SM3 : Advanced Biomaterials for Neural Interfaces

2017-04-18   Show All Abstracts

Symposium Organizers

Mohammad Reza Abidian, University of Houston
Stephanie Lacour, Ecole Polytechnique Federale de Lausanne, Switzerland
Kip Ludwig, Mayo Clinic
Laura Poole-Warren, University of New South Wales
SM3.1/SM1.1/SM4.1: Joint Session I
Session Chairs
Mohammad Reza Abidian
Martin Kaltenbrunner
Jonathan Rivnay
Tuesday AM, April 18, 2017
PCC North, 100 Level, Room 121 AB

10:30 AM - *SM3.1.01/SM1.1.01/SM4.1.01
Nano-Bioelectronics: From Biological Sensor Chips to Cyborg Tissues and Seamless Brain-Electronics Implants

Charles Lieber 1 , Jae-hyun Lee 1
1 , Harvard University, Cambridge, Massachusetts, United States

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11:00 AM - *SM3.1.02/SM1.1.02/SM4.1.02
Soft Wearable Robots Improve Walking Function and Economy after Stroke and Grasping Function after Spinal Cord Injury

Conor Walsh 1
1 , Harvard School of Engineering, Cambridge, Massachusetts, United States

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SM3.2/SM1.2/SM4.2: Joint Session II: Bioelectronics
Session Chairs
Mohammad Reza Abidian
Martin Kaltenbrunner
Jonathan Rivnay
Tuesday PM, April 18, 2017
PCC North, 100 Level, Room 121 AB

1:30 PM - *SM3.2.01/SM1.2.01/SM4.2.01
Skin-Inspired Materials, Devices and Applications

Zhenan Bao 1
1 , Stanford University, Stanford, California, United States

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2:00 PM - *SM3.2.02/SM1.2.02/SM4.2.02
Biocompatible Gel Electrodes and Ultraflexible Organic Devices for Implantable Electronics

Takao Someya 1 , Tsuyoshi Sekitani 2 , Sungwon Lee 3 , Tomoyuki Yokota 1
1 Electrical and Electronic Engineering and Information Systems, University of Tokyo, Tokyo Japan, 2 The Institute of Scientific and Industrial Research, Osaka University, Osaka Japan, 3 , Daegu Gyeongbuk Institute of Science and Technology, Daegu Korea (the Republic of)

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2:30 PM - *SM3.2.03/SM1.2.03/SM4.2.03
Interfacing with the Brain Using Organic Electronics

George Malliaras 1
1 , ENSM Saint-Etienne, Gardanne France

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3:00 PM -
BREAK

3:30 PM - *SM3.2.04/SM1.2.04/SM4.2.04
Materials and Devices Designs for Flexible, Active Electronic Interfaces to the Brain and the Heart

John Rogers 1
1 , Northwestern University, Evanston, Illinois, United States

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4:00 PM - *SM3.2.05/SM1.2.05/SM4.2.05
Conformal, Microfabricated Electrode Array for Optimization of Spectral Content in the Auditory Brainstem Implant (ABI)

Amelie Guex 1 , Ariel Hight 2 , Daniel Lee 2 , M. Brown 2 , Stephanie Lacour 1
1 , Ecole Polytechnique Federale de Lausanne, Switzerland, Lausanne Switzerland, 2 , Harvard Medical School, Boston, Massachusetts, United States

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4:30 PM - *SM3.2.06/SM1.2.06/SM4.2.06
Interfacing Neurons with Electronic Devices

Andreas Offenhaeusser 1
1 , Forschungszentrum Juelich, Juelich Germany

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2017-04-19   Show All Abstracts

Symposium Organizers

Mohammad Reza Abidian, University of Houston
Stephanie Lacour, Ecole Polytechnique Federale de Lausanne, Switzerland
Kip Ludwig, Mayo Clinic
Laura Poole-Warren, University of New South Wales
SM3.3: Neural Interfaces I
Session Chairs
Mohammad Reza Abidian
Laura Poole-Warren
Wednesday AM, April 19, 2017
PCC North, 100 Level, Room 121 C

8:30 AM - SM3.3.01
Curvature-Dependent Neuronal Membrane Deformation Probed by Correlative Fluorescence and Electron Microscopy

Francesca Santoro 1 , Wenting Zhao 1 2 , Hsin-ya Lou 1 , Bianxiao Cui 1
1 Chemistry, Stanford University, Stanford, California, United States, 2 Material Science and Engineering, Stanford University, Stanford, California, United States

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8:45 AM - SM3.3.02
A Novel Polymeric Retinal Prosthesis Restores Vision in a Rat Model of Degenerative Blindness

Maria Rosa Antognazza 1
1 , Istituto Italiano di Tecnologia, Milano Italy

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9:00 AM - *SM3.3.03
CMOS Neural Probes

Ken Shepard 1
1 Electrical Engineering, Columbia, New York, New York, United States

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9:30 AM - *SM3.3.04
Stability and Reliability of Neural Implants—A View from Materials to Systems

Thomas Stieglitz 1
1 Laboratory for Biomedical Microtechnology, Department of Microsystems Engineering – IMTEK, University of Freiburg, Freiburg Germany

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10:00 AM -
BREAK

10:30 AM - *SM3.3.05
Communication with Neurons—New Materials and New Dimensions

Gordon Wallace 1 , David Officer 1
1 ARC Centre of Excellence for Electromaterials Science, Intelligent Polymer Research Institute, AIIM Facility, Innovation Campus, University of Wollongong, Wollongong, New South Wales, Australia

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11:00 AM - SM3.3.06
Fabrication of 3D Neural Probes Using Photolithography in Fibers

Andres Canales 1 , Marc-Joseph Antonini 1 , Gregory Ellson 2 , Yoel Fink 1 , Polina Anikeeva 1
1 , Massachusetts Institute of Technology, Cambridge, Massachusetts, United States, 2 , University of Texas at Dallas, Dallas, Texas, United States

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11:15 AM - SM3.3.07
Coupling of Active and Passive 1D Nanostructure Devices to Record Neuronal Activity—From Extra to Intracellular Interfacing

Adrien Casanova 1 , Marie-Charline Blatche 1 , Fabrice Mathieu 1 , Aurelie Lecestre 1 , Laurent Mazenq 1 , Cecile Ferre 2 , Daniel Gonzalez-Dunia 2 , Liviu Nicu 1 , Guilhem Larrieu 1
1 , LAAS-CNRS, Université de Toulouse, CNRS, Toulouse France, 2 INSERM UMR 1043, CNRS UMR 5282, Université Toulouse, Toulouse France

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11:30 AM - *SM3.3.08
Nano-Fractal Platinum-Iridium Bioelectrodes

James Weiland 1 , John Whalen 2 , Artin Petrossians 1
1 , University of Southern California, Los Angeles, New York, United States, 2 , Platinum Group Coatings, Pasadena, California, United States

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SM3.4: Neural Interfaces II
Session Chairs
Kip Ludwig
Wednesday PM, April 19, 2017
PCC North, 100 Level, Room 121 C

2:00 PM - SM3.4.01
From Soft and Stretchable Conductive Materials to a Fully Functional Neuromodulation Device

Mattia Marelli 1 , Alessandro Antonini 1 , Marta Ferri 1 , Cristian Ghisleri 1 , Ilaria Pietta 1 , Laura Spreafico 1 , Luca Ravagnan 1 , Sandro Ferrari 1
1 , WISE, Milan Italy

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2:15 PM - SM3.4.02
Investigation of Glassy Carbon Microelectrode Arrays for Multi-Analyte Biosensing Applications

Maria Vomero 1 3 , Danesh Ashouri 1 4 , Calogero Gueli 1 , Sam Kassegne 2 3 , Thomas Stieglitz 1 4
1 IMTEK-BMT, University of Freiburg, Freiburg Germany, 3 , Center for Sensorimotor Neural Engineering, Seattle, Washington, United States, 4 , Exzellenzcluster BrainLinks-BrainTools, Freiburg Germany, 2 Mechanical Engineering, San Diego State University, San Diego, California, United States

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2:30 PM -
BREAK

3:30 PM - SM3.4.03
Integration of Microfluidic Channels for Hybrid Drug-Delivery Mechanism in Mechanically-Adaptive Neural Probes

Allison Hess-Dunning 1 2 , Joseph Lerchbacker 1 2
1 Rehabilitation Research and Development, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, United States, 2 , Advanced Platform Technology Center, Cleveland, Ohio, United States

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3:45 PM - SM3.4.04
Removal of Targeted Pathway on Blood-Derived Immune Cells Improves Intracortical Recordings

Hillary Bedell 1 , Shushen Lin 1 , Ashley Rein 1 , Xujia Li 1 , Emily Molinich 1 , Jeffrey Capadona 1
1 , Case Western Reserve University, Cleveland, Ohio, United States

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4:00 PM - *SM3.4.05
Overview of NIH-Funded Material and Device Advances as well as Future Opportunities in Neural Interfaces

Nick Langhals 1
1 , National Institute of Neurological Disorders and Stroke (NINDS), Bethesda, Maryland, United States

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4:30 PM - SM3.4.06
MEASSuRE—A Novel Tool to Mechanically Stretch and Record Electrophysiological Activity and Image Cells, all at the Same Time

Oliver Graudejus 1 2 , Ruben Ponce Wong 2 , Sonali Ahuja 3 , Adam Pak 1 , Sigurd Wagner 4 , Barclay Morrison 3
1 , Arizona State University, Phoenix, Arizona, United States, 2 , BMSEED LLC, Phoenix, Arizona, United States, 3 Biomedical Engineering, Columbia University, New York, New York, United States, 4 Electrical Engineering, Princeton University, Princeton, New Jersey, United States

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2017-04-20   Show All Abstracts

Symposium Organizers

Mohammad Reza Abidian, University of Houston
Stephanie Lacour, Ecole Polytechnique Federale de Lausanne, Switzerland
Kip Ludwig, Mayo Clinic
Laura Poole-Warren, University of New South Wales
SM3.5: Neural Interfaces III
Session Chairs
Mohammad Reza Abidian
Laura Poole-Warren
Thursday AM, April 20, 2017
PCC North, 100 Level, Room 121 C

9:00 AM - *SM3.5.01
Molecular Design, Synthesis, Microstructure, Mechanics, and Transport Behavior of Functionalized Conjugated Polymers for Biomedical Devices

David Martin 1 , Vivek Subramanian 1 , Liangqi Ouyang 2 , Jinglin Liu 1 , Bin Wei 1 , Jing Qu 1 , Chin-Chen Kuo 1 , Dimitrios Koutsouras 3 , George Malliaras 3
1 , University of Delaware, Newark, Delaware, United States, 2 , Linkopping University, Linkopping Sweden, 3 Bioelectronics, Ecole des Mines de Saint Etienne, Gardanne France

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9:30 AM - *SM3.5.02
Biomimetic Neural Implant Design towards Seamless Tissue Interface

Xinyan Cui 1
1 , University of Pittsburgh, Pittsburgh, Pennsylvania, United States

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10:00 AM -
BREAK

10:30 AM - SM3.5.03
All-in-One Fabrication Process of a Rigidified Flexible Neural Probe

Jolien Pas 1 , Marc Ferro 1 2 , George Malliaras 1
1 Bioelectronics, EMSE, Gardanne, Bouche-du-Rhone, France, 2 Materials Science and Engineering and of Photon Science, Stanford University, Stanford, California, United States

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10:45 AM - SM3.5.04
Conducting Polymer Nanotubes for Axonal Guidance

Milad Khorrami 1 , Mohammad Reza Abidian 1
1 , University of Houston, Houston, Texas, United States

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11:00 AM - SM3.5.05
Conducting Polymers for Axonal Regeneration—Effect of Surface Topography on Neurite Outgrowth

Martin Antensteiner 1 , Mohammad Reza Abidian 1
1 , University of Houston, Houston, Texas, United States

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11:15 AM - SM3.5.06
Implantable OECT-Based Metabolic Sensors for In Vivo Prediction of Seizure Onset

Mary Donahue 1 , Xenofon Strakosas 1 , Adam Williamson 2 , Marcel Braendlein 1 , Christophe Bernard 2 , George Malliaras 1
1 , ENS Mines-St. Etienne, Gardanne France, 2 Inserm, Aix Marseille University, Marseille France

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SM3.6: Neural Interfaces IV
Session Chairs
Kip Ludwig
Thursday PM, April 20, 2017
PCC North, 100 Level, Room 121 C

1:30 PM - *SM3.6.01
Nanofiber-Based Conduits with a Honeycomb Structure for Peripheral Nerve Repair

Younan Xia 1
1 , Georgia Institute of Technology, Atlanta, Georgia, United States

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2:00 PM - SM3.6.02
Conductive Elastomeric Electrodes for Interfacing with Peripheral Nervous System

Kevin Woeppel 1 2 , Sally Zheng 1 , Brady Clapsaddle 3 , Michael Looker 3 , Emily Chang 3 , Xinyan Cui 1 2
1 Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, United States, 2 Center for Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, Pennsylvania, United States, 3 , TDA Research, Inc., Golden, Colorado, United States

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2:15 PM - SM3.6.03
Hydrogel-Elastomer Hybrid Material with Tunable Mechanical Properties for Intracortical Probe

Jennifer Macron 1 , Aaron Lee 1 , Stephanie Lacour 1
1 , Bertarelli Foundation Chair in Neuroprosthetic Technology, Laboratory for Soft Bioelectronic Interfaces, Centre for Neuroprosthetics, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne Switzerland

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2:30 PM -
BREAK

3:00 PM - *SM3.6.04
Materials-Based, Biologically-Inspired, Anti-oxidative, Anti-Inflammatory Approaches to Enable Next-Generation Intracortical Microelectrodes

Jeffrey Capadona 1 2 , Andrew Shoffstall 2 1 , John Hermann 1 2 , Evon Ereifej 2 1
1 , Case Western Reserve University, Cleveland, Ohio, United States, 2 RR&D, Department of Veterans Affairs, Cleveland, Ohio, United States

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3:30 PM - *SM3.6.05
Organic Mixed Conductors for Bioelectronic Applications

Jonathan Rivnay 1
1 Department of Biomedical Engineering, Northwestern University, Evanston, Illinois, United States

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4:00 PM - SM3.6.06
Thermal Damage to the Blood-Brain Barrier during Craniotomy Procedure—Implications for Intracortical Recording Microelectrodes

Andrew Shoffstall 2 1 , Jennifer Paiz 1 , David Miller 1 , Mitchell Willis 1 , Griffin Rial 1 , Dhariyat Menendez 1 , Jeffrey Capadona 2 1
2 Advanced Platform Technology Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, United States, 1 Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, United States

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SM3.7: Poster Session: Neural Interfaces
Session Chairs
Mohammad Reza Abidian
Kip Ludwig
Thursday PM, April 20, 2017
Sheraton, Third Level, Phoenix Ballroom

8:00 PM - SM3.7.01
Invasive Microscale Probe for Intracellular Measurements

Manjunath Rajagopal 1 , Sanjiv Sinha 1
1 Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States

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8:00 PM - SM3.7.02
Highly Durable PEDOT-Based Medical Coatings for Recording and Stimulating Electrodes

Nandita Bhagwat 1 , Melanie Gupte 1 , Clayton Lepak 1 , Jeff Hendricks 1
1 , Biotectix, Richmond, California, United States

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8:00 PM - SM3.7.03
Rupture Characteristics of Elastically Stretchable Microcracked Gold Conductors for Stretchable Microelectrode Array Applications

Adam Pak 1 , Ruben Ponce Wong 2 , James Abbas 3 , Oliver Graudejus 2 4
1 School for Engineering of Matter, Transport, and Energy, Arizona State University, Tempe, Arizona, United States, 2 , BMSEED LLC, Phoenix, Arizona, United States, 3 Center for Adaptive Neural Systems, School of Biological and Health Systems Engineering, Arizona State University, Tempe, Arizona, United States, 4 School of Molecular Sciences, Arizona State University, Tempe, Arizona, United States

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8:00 PM - SM3.7.04
Therapeutic Inhibition of Innate Immunity to Improve Intracortical Microelectrode Longevity

John Hermann 1 2 , Jeremy Chang 1 , Dawn Taylor 3 2 1 , Jeffrey Capadona 1 2
1 Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, United States, 2 Rehabilitation Research and Development, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, United States, 3 Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States

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8:00 PM - SM3.7.05
Self-Softening Shape Memory Polymers as a Scaffold for Neural Electrodes

Melanie Ecker 1 , Vindhya Danda 2 , Joseph Pancrazio 2 , Walter Voit 1 2
1 Materials Science and Engineering, The University of Texas at Dallas, Richardson, Texas, United States, 2 Department of Bioengineering, The University of Texas at Dallas, Richardson, Texas, United States

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8:00 PM - SM3.7.06
Wet Chemical Synthesis of IrOx Film for Biostimulating Interface

Kuang-Chih Tso 1 , Han Yi Wang 1 , PuWei Wu 2 , Po Chun Chen 3 , Jyh Fu Lee 4
1 National Chiao Tung University, Hsinchu, Taiwan, R.O.C, Graduate Program for Science and Technology of Accelerator Light Source, Hsinchu Taiwan, 2 , Department of Materials Science and Engineering National Chiao Tung University, Hsinchu, Taiwan, R.O.C., Hsinchu Taiwan, 3 , Department of Materials and Mineral Resources Engineering National Taipei University of Technology, Taipei, Taiwan, R.O.C., Taipei Taiwan, 4 , National Synchrotron Radiation Research Center, Hsinchu, Taiwan, R.O.C., Hsinchu Taiwan

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8:00 PM - SM3.7.07
Connected Node Engineering of Neuronal Systems Using Laser Direct Write

Benjamin Vinson 1 , Samuel Sklare 2 , Jayant Saksena 3 , Jabe Curley 3 , Michael Moore 3 , Douglas Chrisey 2
1 Bioinnovation Program, Tulane University, New Orleans, Louisiana, United States, 2 Physics and Engineering Physics, Tulane University, New Orleans, Louisiana, United States, 3 Biomedical Engineering, Tulane University, New Orleans, Louisiana, United States

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8:00 PM - SM3.7.08
Investigating the Biostability of Three-Dimensional Graphene Foam for Regenerative Neural Stem Cell Culture

Tanveer Tabish 1 , Sakineh Chabi 2 , David Horsell 1 , Yongde Xia 1 , Chris Scotton 3 , Shaowei Zhang 1
1 College of Engineering Mathematics and Physical Sciences, University of Exeter, Exeter United Kingdom, 2 Department of Chemistry, Florida Institute of Technology, Melbourne, Florida, United States, 3 Institute of Biomedical and Clinical Science, University of Exeter, Exeter United Kingdom

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8:00 PM - SM3.7.09
Architectural Surface Modifications of Intracortical Microelectrode for Reduced Foreign Body Response

Evon Ereifej 2 1 , Cara Smith 2 1 , Seth Meade 2 1 , Keying Chen 2 1 , Jeffrey Capadona 2 1
2 Biomedical Engineering, Case Western Reserve University , Cleveland, Ohio, United States, 1 APT Cen, Veteran Affairs Medical Center, Cleveland , Ohio, United States

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