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2015 MRS Fall Meeting Logo2015 MRS Fall Meeting & Exhibit

November 29-December 4, 2015 | Boston
Meeting Chairs: T. John Balk, Ram Devanathan, George G. Malliaras, Larry A. Nagahara, Luisa Torsi

Symposium L—Nanofunctional Materials, Nanostructures and Nanodevices for Biomedical Applications

Many debilitating and deadly diseases (e.g., Alzheimer, AIDS, cancer, H1N1, etc.) affect tens of millions of people worldwide every year. The need for breakthrough materials and technologies, which have the potential to significantly impact conventional treatment and contribute to improved methodologies toward prevention, diagnostics, imaging, and therapies, is challenging. In order to address this challenge, scientists, engineers, and medical researchers have looked to nanotechnology as a possible disruptive paradigm, offering hope for those afflicted with one of these diseases. A multifunctional nanodevice capable of detecting disease at its earliest stages, pinpointing its location within the body, and delivering therapeutics, is one long-term vision shared by many for in-vivo application. Consequently, research in this field brings together synthesis of nanofunctional materials, surface chemistry/coatings, identification of targeting agents, and physical/chemical transduction mechanisms, to name a few. In the case of in-vitro diagnostics and drug discovery, on-chip agent processing (e.g., preconcentration, sifting and separation), nanostructural fabrication, and overall systems integration are additional considerations. However, as with all new technologies, leveraging the unique behavior of nanomaterials, structures, and devices also introduces the potential for unique and unforeseen toxicological impact to patients. Nanomaterials also demand new nanoscale visualization and characterization methods at extremely high spatial and temporal resolution (especially under physiologically relevant conditions such as fluidic environment); as well as concomitant “big data” handling, management and analysis. This symposium aims at providing opportunities for intensive discussion and exchange of ideas by bringing together researchers in various disciplines to advance medicine using nanotechnology.

Topics will include:

  • Nanomaterials
    • Inorganic and organic nanoparticulate systems
    • Molecular recognition materials, nanotubes and nanowires
    • Self-Assembled biomaterials (e.g., DNA origami)
  • Surface Chemistry and Conjugation
    • High-specificity chemistry and coatings
    • High-affinity ligands, peptides, aptamers, and antibodies
  • In-vitro/In-vivo Imaging/Diagnostic Agents/Devices
    • High resolution, advanced imaging methods (e.g. ETEM, super-resolution microscopy, in-situ/fluidic imaging)
    • Nanoacoustic/nanomagnetic agents
    • Nanophotonic/optical agents
    • Nanothermal/radiological agents
  • Therapeutics Encapulation (e.g., liposome and micelle)
    • Polymer-drug conjugates
    • Photo/thermal treatment
  • Transduction Mechanism
    • Platforms for sensor detection (e.g., optical, electrical and mechanical and other MEMS/NEMS based)
  • On-chip Processes
    • Separation science, magnetic sifting and preconcentration techniques
    • Microfluidics
  • Health and Environmental Concerns
    • Nanomaterial toxicity (in-vivo/in-vitro)
    • Toxicity mechanisms and biodistribution

Invited Speakers:

  • Adam Abate (University of California, San Francisco, USA)
  • Damien Alloyeau (Paris Diderot University, France)
  • Christian Amotore (Universite Pierre et Marie Curie Paris, France)
  • Thomas Lars Andresen (Technical University of Denmark, Denmark)
  • Tejal Desai (University of California, San Francisco, USA)
  • Paul Gatenholm (Chalmers University, Sweden)
  • Piotr Grodzinski (National Institutes of Health, USA)
  • James Heath (California Institute of Technology, USA)
  • Fredrik Höök (Chalmers University of Technology, Sweden)
  • Jesse Jokerst (Stanford University, USA)
  • Paul Kempen (Stanford University, USA)
  • James Kirkpatrick (Gutenberg University, Germany)
  • Richard Leapman (National Institutes of Health, USA)
  • Karen Martinez (University of Copenhagen, Denmark)
  • Scott McNeil (National Institutes of Health, USA)
  • Chad Mirkin (Northwestern University, USA)
  • Christelle Prinz (Lund University, Sweden)
  • Peter Thomsen (Gothenburg University, Sweden)
  • Shan Wang (Stanford University, USA)
  • Peng Yin (Harvard University, USA)
  • Otto Zhou (University of North Carolina at Chapel Hill, USA)
  • Xiaowei Zhuang (Harvard University, USA)

Symposium Organizers

Robert Sinclair
Stanford University
Department of Materials Science and Engineering

Vinayak Dravid
Northwestern University
Department of Materials Science and Engineering

Bo Huang
University of California, San Francisco
Department. of Pharmaceutical Chemistry and Dept. of Biochemistry and Biophysics

Kristian Mølhave
Technical University of Denmark
Department of Micro- and Nanotechnology

Eva Olsson
Chalmers University of Technology
Department of Applied Physics