Symposium BM07—Emerging Materials and Devices for Engineering Biological Function and Dynamics

Biomaterials and devices that establish functional interactions with biological components at various length scales, with the goal of modulating and probing the biological system, are highly sought after. Modern bio-integrated systems offer the capability for either recording or modulating molecular or cellular behaviors in three-dimensions and/or with high spatiotemporal resolutions. Advances in protein engineering and synthetic macromolecular design have, and will continue to enable precise regulation of biomolecule activities and biological pathways. All together, these materials and devices under development by scientists and engineers hold promise for assisting physicians in their effort to treat a variety of ailments, from Type 2 diabetes to traumatic spinal injuries and cancer. However, in order to engineer and translate these materials into functional devices and therapeutics, an extensive collaborative effort is required between scientists, engineers and physicians.

This symposium will assemble experts in key thematic areas to highlight several classes of emerging materials and devices used to engineer biological function and dynamics. In particular, it will cover systems such as synthetic and biologically derived nanoparticles, engineered biopolymers, nanoscale imaging probes, semiconductors and flexible electronics, and a number of preclinical and clinical treatment modalities including image-guided therapy and tissue regeneration. The overall goal will be to seed collaborative efforts that will accelerate translation of these emerging materials and devices into therapeutics to reduce the burden of disease on human health.

Topics will include:

  • Biomaterials for therapeutic applications
  • Synthetic mimics of biological structures/scaffolds
  • Semiconductor-based biomaterials
  • Engineering macromolecular therapeutics
  • Nanomaterials for probing biology

Invited Speakers:

  • Morgan Alexander (The University of Nottingham, United Kingdom)
  • Polina Anikeeva (Massachusetts Institute of Technology, USA)
  • Debra Auguste (City College of New York, USA)
  • Zhenan Bao (Stanford University, USA)
  • Jianjun Cheng (University of Illinois Urbana-Champaign, USA)
  • Dennis Discher (University of Pennsylvania, USA)
  • Tal Dvir (Tel Aviv University, Israel)
  • Jinming Gao (University of Texas Southwestern Medical Center, USA)
  • Alon Gorodetsky (University of California, Irvine, USA)
  • Leaf Huang (University of North Carolina at Chapel Hill, USA)
  • Stéphanie Lacour (École Polytechnique Fédérale de Lausanne, Switzerland)
  • Oren Levy (Brigham and Women’s Hospital, USA)
  • Xing-Jie Liang (The National Center for Nanoscience and Technology, China)
  • David Mooney (Harvard University, USA)
  • Dehua Pei (The Ohio State University, USA)
  • Tijana Rajh (Argonne National Laboratory, USA)
  • John Rogers (Northwestern University, USA)
  • Molly Stevens (Imperial College London, United Kingdom)
  • Jun Wang (South China University of Technology, China)
  • Kathryn/A Whitehead (Carnegie Mellon University, USA)
  • Yoon Yeo (Purdue University, USA)
  • Gang Zheng (University of Toronto, Canada)

Symposium Organizers

Yizhou Dong
The Ohio State University
College of Pharmacy

Christopher A. Alabi
Cornell University
Chemical and Biomolecular Engineering

Daniel G. Anderson
Massachusetts Institute of Technology
Chemical Engineering and Institute for Medical Engineering and Science

Bozhi Tian
University of Chicago