Symposium Organizers
Christine Selhuber-Unkel, University of Kiel
Jennifer Curtis, Georgia Institute of Technology
Matthew Paszek, Cornell University
Kate Poole, University of New South Wales
SB06.01: Cells as Mechanosensory Living Materials I
Session Chairs
Christine Selhuber-Unkel
Ana-Sucana Smith
Monday AM, December 02, 2019
Hynes, Level 2, Room 201
8:30 AM - *SB06.01.01
Sensing Local Strains in the Cytoskeleton via LIM Domains
Patrick Oakes1
Loyola University Chicago Stritch School of Medicine1
Show AbstractAbstracts will be published on November 4.
9:00 AM - SB06.01.02
Mechanical Manipulation of Tandem Repeats of Biological Motifs—One Molecule at a Time
Jaba Mitra1,2,Taekjip Ha2
University of Illinois at Urbana-Champaign1,Johns Hopkins University2
Show AbstractAbstracts will be published on November 4.
9:15 AM - SB06.01.03
Biologically Inspired, Cell–Selective Release of Aptamer–Trapped Growth Factors by Traction Forces
Benjamin Almquist1
Imperial College London1
Show AbstractAbstracts will be published on November 4.
9:30 AM - *SB06.01.04
Watching Cellular Mechanotransduction—Piezo1 Activation by Cellular Traction Forces
Medha Pathak2,Kyle Ellefsen1,Jesse Holt2,Alice Chang3,Jamison Nourse2,Janahan Arulmoli2,Armen Mekhdjian3,Hamid Abuwarda2,Francesco Tombola2,Lisa Flanagan2,Alexander Dunn3,Ian Parker1
University of California1,University of California, Irvine2,Stanford University3
Show AbstractAbstracts will be published on November 4.
10:30 AM - *SB06.01.05
From Microdishes to Microniches—Controlling Single Cell Apico-Basal Polarity and Lumenogenesis
Virgile Viasnoff1,2,Yue Zhang1,Richard deMets1,Celine Stoecklin1
National University of Singapore1,Centre National de la Recherche Scientifique2
Show AbstractAbstracts will be published on November 4.
11:00 AM - *SB06.01.06
Mechanism in Collective Organizations of Living Cells
Joachim Spatz1
Max Planck Institute for Medical Research1
Show AbstractAbstracts will be published on November 4.
11:30 AM - *SB06.01.07
Soft Tissue Mechanics Result from Fibrous Networks Confined by Close-Packed Cells
Paul Janmey1,Anne van Oosten1,2,Xingyu Chen1,Vivek Shenoy1
University of Pennsylvania1,Leiden University2
Show AbstractAbstracts will be published on November 4.
SB06.02: Cell Adhesion and Mechanics
Session Chairs
Christine Selhuber-Unkel
Britta Trappmann
Monday PM, December 02, 2019
Hynes, Level 2, Room 201
1:30 PM - *SB06.02.01
Single-Molecule Measurements of Force Transmission by Integrin Heterodimers in Living Cells
Alexander Dunn1
Stanford University1
Show AbstractAbstracts will be published on November 4.
2:00 PM - SB06.02.02
Multiscale Modeling of the Facet Capsule Ligament—Size Effects and Problem Size Reduction through Generalized Boundary Conditions
Jacob Merson1,Catalin Picu1
Rensselaer Polytechnic Institute1
Show AbstractAbstracts will be published on November 4.
2:15 PM - SB06.02.03
Towards Non-Optical, Label-Free Measurements of Particle and Cell Stiffness in Flow
Charles Dhong1,Darren Lipomi2
University of Delaware1,University of California, San Diego2
Show AbstractAbstracts will be published on November 4.
2:30 PM - *SB06.02.04
Local Catalytic Effects in Adherent Membranes
Ana-Sucana Smith1
FAU Erlangen-Nürnberg1
Show AbstractAbstracts will be published on November 4.
SB06.03: Tools to Study Mechanotransduction
Session Chairs
Matthew Paszek
Medha Pathak
Monday PM, December 02, 2019
Hynes, Level 2, Room 201
3:30 PM - *SB06.03.01
Synthetic Extracellular Matrices to Study Mechanotransduction in 3D
Britta Trappmann1
Max Planck Institute for Molecular Biomedicine1
Show AbstractAbstracts will be published on November 4.
4:00 PM - SB06.03.02
A Sensitive Tool for Probing Cellular Mechanics—Tracking Longitudinal Rotation with a Kinked-Silicon Nanowire
Youjin Lee1,David Wu1,Yuxing Peng1,Bozhi Tian1
The University of Chicago1
Show AbstractAbstracts will be published on November 4.
4:15 PM - SB06.03.03
NIR-Actuated Composites to Perturb and Profile Mechano-Chemical Cell Signaling
Rachel Steinhardt1,Nicholas Vishnosky1
Syracuse University1
Show AbstractAbstracts will be published on November 4.
4:30 PM - *SB06.03.04
A Materials Approach to Studying Forces, Form and Function in Cells and Tissues
Christopher Chen1,2
Boston University1,Harvard University2
Show AbstractAbstracts will be published on November 4.
SB06.04: Poster Session I: Bringing Mechanobiology to Materials—From Molecular Understanding to Biological Design I
Session Chairs
Monday PM, December 02, 2019
Hynes, Level 1, Hall B
8:00 PM - SB06.04.01
Towards the Development of a Macroscopic, Biohybrid, Hydrogel-Based Actuator
Christine Arndt1,Mohammadreza Taale1,Florian Ceynowa1,Fabian Schuett1,Rainer Adelung1,Christine Selhuber-Unkel1
Kiel University1
Show AbstractAbstracts will be published on November 4.
8:00 PM - SB06.04.02
Detachment of the Biomolecule Bindings between the Microtubules and Kinesins
Kenta Hatazawa1,Ryuzo Kawamura2,Takayuki Hoshino1
Hirosaki University1,Saitama University2
Show AbstractAbstracts will be published on November 4.
8:00 PM - SB06.04.03
Behavior and Phenotype of Cancer Cells in Response to Varied Mechanical Environment in 3D Hydrogel Models Cultured In Vitro
Jason Nichol1,Tayler Laycox1,Riley Aspinwall1,Ian Schmidt1
Endicott College1
Show AbstractAbstracts will be published on November 4.
8:00 PM - SB06.04.04
The Signaling Response of Artificial Neurons Made from Chemical Oscillators
James Sheehy1,Seth Fraden1
Brandeis University1
Show AbstractAbstracts will be published on November 4.
8:00 PM - SB06.04.05
Characterizing Hetero-Oligomers from Amyloid-Beta and Alpha-Synuclein with AFM
Eun Ji Shin1,Joon Won Park1
Pohang University of Science and Technology1
Show AbstractAbstracts will be published on November 4.
8:00 PM - SB06.04.06
Designed Liquid Crystalline Polypeptide Fibres
Hannah Leese2,1,James MacDonald1,Karan Bali1,Paul Freemont1,Milo Shaffer1
Imperial College London1,University of Bath2
Show AbstractAbstracts will be published on November 4.
8:00 PM - SB06.04.07
Cortex Dominates Bacillus subtilis Spore’s Water-Responsive Behaviors
Zhi-Lun Liu1,Haozhen Wang1,Xi Chen1
The City University of New York1
Show AbstractAbstracts will be published on November 4.
8:00 PM - SB06.04.08
Understanding the Molecular Mechanism of Cartilage Degradation and Cation Channel Activity
Deng Li1,Kai-Chih Yeh1,Yuan Chiang1,Shu-Wei Chang1
National Taiwan University1
Show AbstractAbstracts will be published on November 4.
8:00 PM - SB06.04.09
Nanofibrils as Basic Building Blocks of Natural Spider Silk
Qijue Wang1,Chloe Walsh1,Dinidu Perera1,Hannes Schniepp1
College of William and Mary1
Show AbstractAbstracts will be published on November 4.
8:00 PM - SB06.04.10
Influence of Different Mechanical Conditions on Cell Behavior
Sandra Sindt1,Yasmeen El-Rayyes1,Galen Ream1,Christine Selhuber-Unkel1
Kiel University1
Show AbstractAbstracts will be published on November 4.
8:00 PM - SB06.04.11
Rapid Magnetic Printing of 3D Cell Structures
Sarah Mishriki1,Abdel Rahman Abdel Fattah1,2,Tobias Kammann1,3,Srivatsa Aithal1,Rakesh Sahu1,Fei Geng1,Ishwar Puri1
McMaster University1,KU Leuven2,Friedrich-Schiller-University3
Show AbstractAbstracts will be published on November 4.
8:00 PM - SB06.04.12
Design of Novel Scaffolds for Effective Healing of Bone Fractures Using Topology Optimization Based on Mechano-Biological Model, Angiogenesis and Scaffold Degradation
Mervenaz Sahin1,Mehmet Serhat Aydin1,Gullu Kiziltas Sendur1,2
Sabanci University1,Sabanci University Nanotechnology Research and Application Center2
Show AbstractAbstracts will be published on November 4.
8:00 PM - SB06.04.13
Modulation of Chemical Reactivity by Strong Coupling to Molecular Vibrations
Wonmi Ahn1,2,Igor Vurgaftman2,Adam Dunkelberger2,Jeffrey Owrutsky2,Blake Simpkins2
Excet Inc.1,U.S. Naval Research Laboratory2
Show AbstractAbstracts will be published on November 4.
Symposium Organizers
Christine Selhuber-Unkel, University of Kiel
Jennifer Curtis, Georgia Institute of Technology
Matthew Paszek, Cornell University
Kate Poole, University of New South Wales
SB06.05: Hot Topics in Bringing Mechanobiology to Materials
Session Chairs
Matthew Paszek
Christine Selhuber-Unkel
Tuesday AM, December 03, 2019
Hynes, Level 2, Room 201
8:00 AM - SB06.05.01
Nanowire-Based Spatio-Mechano-Chemical Guidance of the Cell Immune Activity
Mark Schvartzman1,Viraj Bhingardive1,Guillaume Le Saux1
Ben-Gurion University of the Negev1
Show AbstractAbstracts will be published on November 4.
8:15 AM - SB06.05.02
Extracellular Matrix Plasticity as a Driver of Cell Spreading
Joshua Grolman1,Philipp Weinand1,David Mooney1
Harvard University1
Show AbstractAbstracts will be published on November 4.
8:30 AM - *SB06.06.01
Photoresponsive Materials for Resolving Mechanobiology in Collective Cell Migration
Jun Nakanishi1
National Institute for Materials Science1
Show AbstractAbstracts will be published on November 4.
9:00 AM - SB06.06.02
Dynamic, Reversible Control of Biomaterial Properties Using DNA
Nicholas Stephanopoulos1
Arizona State University1
Show AbstractAbstracts will be published on November 4.
9:15 AM - SB06.06.03
Design and Development of Mechanobiological Gels That Can Control Mechanical Property
Takeshi Ueki1,Ryota Tamate1,Aya Akimoto2,Ryo Yoshida2,Jun Nakanishi1
National Institute for Materials Science1,The University of Tokyo2
Show AbstractAbstracts will be published on November 4.
9:30 AM - *SB06.06.04
Building with Cells—Exploiting Mechanobiology to Use Living Cells as an Engineering Material
Kevin Kit Parker1
Harvard University1
Show AbstractAbstracts will be published on November 4.
SB06.07: Bioinspired and Biofunctional Materials
Session Chairs
Cornelia Lee-Thedieck
Angela Pitenis
Tuesday AM, December 03, 2019
Hynes, Level 2, Room 201
10:30 AM - *SB06.07.01
Bioinspired Materials for Deconstructing Matrix Structure-Cell Function Relationships
Kristopher Kilian1
University of New South Wales1
Show AbstractAbstracts will be published on November 4.
11:00 AM - SB06.07.02
The Adaptive Behavior of Cells as Archetype for Novel Strain-Stiffening Structures
Michael Timmermann1,Leonard Siebert1,Rainer Adelung1,Christine Selhuber-Unkel1
University of Kiel1
Show AbstractAbstracts will be published on November 4.
11:15 AM - SB06.07.03
Stiff and Responsive Hybrid Bacterial Assemblies through Covalent Crosslinking of Nanoparticles to Engineered Bacterial S-Layer Proteins
Dong Li1,Marimikel Charrier1,Sneha Jani1,Behzad Rad1,Bruce Cohen1,Kathleen Ryan2,Caroline Ajo-Franklin1,Paul Ashby1
Lawrence Berkeley National Laboratory1,University of California, Berkeley2
Show AbstractAbstracts will be published on November 4.
11:30 AM - SB06.07.04
Adhesion of Cells to Ferromagnetic Shape Memory Alloys Functionalized with
Plasma Assembled Biomolecules—A Single Force Spectroscopy Study
Stefan Mayr2,1,M. V. Cakir1,U. Allenstein2,1,M. Zink1
University of Leipzig1,Leibniz Institute of Surface Engineering2
Show AbstractAbstracts will be published on November 4.
11:45 AM - SB06.07.05
Microfluidic Fabrication of Asymmetric Lipid and Polymer Vesicles
Yuting Huang1,David Weitz1
Harvard University1
Show AbstractAbstracts will be published on November 4.
SB06.08: Synthetic Mechanoresponsive Materials
Session Chairs
Patrick Oakes
Matthew Paszek
Tuesday PM, December 03, 2019
Hynes, Level 2, Room 201
1:30 PM - *SB06.08.01
Force Amplification in Mechanochemically Active Polymers
Nancy Sottos1,Tae Ann Kim1,Jaeuk Sung1,Jeffrey Moore1
University of Illinois at Urbana-Champaign1
Show AbstractAbstracts will be published on November 4.
2:00 PM - SB06.08.02
Engineering Elasticity Inspired by Natural Biopolymers
Anna Tarakanova1
University of Connecticut1
Show AbstractAbstracts will be published on November 4.
2:15 PM - SB06.08.03
Morphogenic Patterning in Synthetic Polymers
Evan Lloyd1,2,Adam Feinberg1,2,Philippe Geubelle1,2,Nancy Sottos1,2,Jeffrey Moore1,2
University of Illinois at Urbana-Champaign1,Beckman Institute for Advanced Science and Technology2
Show AbstractAbstracts will be published on November 4.
2:30 PM - *SB06.08.04
Embodied Intelligence and Energy in Autonomous Matter
Rob Shepherd1
Cornell University1
Show AbstractAbstracts will be published on November 4.
SB06.09: Soft Materials for Biomedicine
Session Chairs
Alexander Dunn
Patrick Oakes
Tuesday PM, December 03, 2019
Hynes, Level 2, Room 201
3:30 PM - *SB06.09.01
Cells, Gels and Shear—Designing Soft Materials for Biomedicine
Angela Pitenis1
University of California, Santa Barbara1
Show AbstractAbstracts will be published on November 4.
4:00 PM - SB06.09.02
Mechanically Tunable Structured Hydrogels and Their Impact on Cells
Katharina Siemsen1,Chanh Hu Trinh1,Florian Ceynowa1,Rainer Adelung1,Jan Lammerding2,Christine Selhuber-Unkel1
Kiel University1,Cornell University2
Show AbstractAbstracts will be published on November 4.
4:15 PM - SB06.09.03
Hyper-Activation of Cellular Rigidity Sensing Pathways by the Surface Tension of Biomedical Silicones
Zhu Cheng1,Carolyn Shurer1,Samuel Schmidt1,Vivek Gupta1,Grace Chuang1,Jin Su1,Amanda Watkins1,Jason Spector1,Chung-Yuen Hui1,Heidi Reesink1,Matthew Paszek1
Cornell University1
Show AbstractAbstracts will be published on November 4.
4:30 PM - *SB06.09.04
Mechanobiology in the Hematopoietic Stem Cell Niche
Cornelia Lee-Thedieck1
Leibniz University Hannover1
Show AbstractAbstracts will be published on November 4.
Symposium Organizers
Christine Selhuber-Unkel, University of Kiel
Jennifer Curtis, Georgia Institute of Technology
Matthew Paszek, Cornell University
Kate Poole, University of New South Wales
SB06.10/SB09.08: Joint Session: Mechanics of Cancer Invasion
Session Chairs
Ming Guo
Jan Lammerding
Susan Leggett
Ian Wong
Wednesday AM, December 04, 2019
Hynes, Level 3, Room 304
8:30 AM - *SB06.10.01/SB09.08.01
Cell-Matrix Interactions in Cancer and Fibrosis—Multiscale Chemo-Mechanical Models
Vivek Shenoy1
University of Pennsylvania1
Show AbstractAbstracts will be published on November 4.
9:00 AM - *SB06.10.02/SB09.08.02
Biomechanical Imaging of Cancer Cells and Tumor Development in 3D
Ming Guo1
Massachusetts Institute of Technology1
Show AbstractAbstracts will be published on November 4.
9:30 AM - SB06.10.03/SB09.08.03
3D Traction Force Microscopy of Multicellular Invasion in Biomimetic Silk-Collagen Hydrogels
Susan Leggett1,Mohak Patel1,Thomas Valentin1,Christian Franck2,Ian Wong1
Brown University1,University of Wisconsin–Madison2
Show AbstractAbstracts will be published on November 4.
9:45 AM - SB06.10.04/SB09.08.04
Unjamming and Collective Migration in MCF10A Series of Breast Cancer Cell Lines
Jae Hun Kim1,Jeffrey Fredberg1
Harvard University1
Show AbstractAbstracts will be published on November 4.
10:30 AM - *SB06.10.05/SB09.08.05
Mechanical Forces, the Microenvironment and Metastasis of 3D Microtumors
Celeste Nelson2,Joe Tien1
Boston University1,Princeton Univ2
Show AbstractAbstracts will be published on November 4.
11:00 AM - *SB06.10.06/SB09.08.06
Engineered Microfluidic Environments to Study the Role of Nuclear Mechanobiology in Cancer Progression
Jan Lammerding1
Cornell University1
Show AbstractAbstracts will be published on November 4.
11:30 AM - *SB06.10.07/SB09.08.07
The National Cancer Institute’s Support for the Interface of Bio/Nano Materials with Cancer Research
Nas Zahir1
National Cancer Institute1
Show AbstractAbstracts will be published on November 4.
SB06.11/SB09.09: Joint Session: Cancer Cell—ECM Interactions
Session Chairs
Matthew Paszek
John Slater
Nas Zahir
Wednesday PM, December 04, 2019
Hynes, Level 3, Room 304
1:30 PM - *SB06.11.01/SB09.09.01
Nuclear Rupture at High Curvature and High Rates Upsets DNA Repair to Affect Cell Cycle, Differentiation and Genome Variation
Dennis Discher1
University of Pennsylvania1
Show AbstractAbstracts will be published on November 4.
2:00 PM - SB06.11.02/SB09.09.02
Invited Presentation by Valerie Weaver
Show AbstractAbstracts will be published on November 4.
3:30 PM - *SB06.11.03/SB09.09.03
Biosynthetic Hydrogels for Islet Engraftment and Immune Acceptance
Andres Garcia1
Georgia Institute of Technology1
Show AbstractAbstracts will be published on November 4.
4:00 PM - *SB06.11.04/SB09.09.04
Viscoelasticity and Cancer
David Mooney1
Harvard University1
Show AbstractAbstracts will be published on November 4.
4:30 PM - SB06.11.05/SB09.09.05
Integrin-Specific Hydrogels Direct Mesenchymal Stem Cell Immunomodulation and Bone Regeneration
Karen Martin1,Amy Clark1,José García1,Christopher Johnson1,2,Hannah Theriault1,Woojin Han1,Dennis Zhou1,Edward Botchwey1,2,Andres Garcia1
Georgia Tech1,Emory University2
Show AbstractAbstracts will be published on November 4.
SB06.12: Poster Session II: Bringing Mechanobiology to Materials—From Molecular Understanding to Biological Design II
Session Chairs
Wednesday PM, December 04, 2019
Hynes, Level 1, Hall B
8:00 PM - SB06.12.01
Elucidating the Effects of Direct Physical Contact between Dental Pulp Stem Cells Cultivated on Polybutadiene with Different Stiffness on Proliferation and Differentiation Behaviors
Yihan Shen1,Zijian Ma2,Ya-Chen Chuang3,4,Jessica Hofflich3,Miriam Rafailovich3,Marcia Simon3
St. Andrew's School1,Tianjin Nankai High School2,Stony Brook University3,ThINC Facility, Advanced Energy Center4
Show AbstractAbstracts will be published on November 4.
8:00 PM - SB06.12.02
Bio-Inspired and Bio-Mimetic Self-Assembled Materials
Sharon Gilead1,Ehud Gaizt1
Tel Aviv University1
Show AbstractAbstracts will be published on November 4.
8:00 PM - SB06.12.03
Investigating Substrate Mechanics Effects in Combination with TiO2 Thin Layer Coated by Atomic Layer Deposition (ALD) for Dental Pulp Stem Cell Proliferation and Differentiation
Megha Gopal1,Jessica Hofflich2,Ya-Chen Chuang2,Miriam Rafailovich2
New Hyde Park Memorial High School1,Stony Brook University, The State University of New York2
Show AbstractAbstracts will be published on November 4.
8:00 PM - SB06.12.04
Shape Memory Cell Culture Platform for Mechanobiology
Koichiro Uto1,Mitsuhiro Ebara1
National Institute for Materials Science1
Show AbstractAbstracts will be published on November 4.
8:00 PM - SB06.12.05
Engineering Tubular Structured Epithelial Organoids by Directed Tissue Assembly
Yan Yan Shery Huang1,Ye Liu1,Joo-Hyeon Lee1,Catherine Dabrowska1
University of Cambridge1
Show AbstractAbstracts will be published on November 4.