2021 MRS Spring Meeting

Meeting content will be available through May 31
at https://mrs2021.cd.pathable.com/.


All times listed are Eastern Daylight Time.

Symposium SM04 : Beyond Nano–Challenges and Opportunities in Drug Delivery

2021-04-20   Show All Abstracts

Symposium Organizers

Yoon Yeo, Purdue University
Yosi Shamay, Technion-Israel Institute of Technology
Youqing Shen, Zhejiang University
Patrick Stayton, University of Washington

Symposium Support

Gold
National Institutes of Health
National Center for Advancing Translational Sciences of the National Institutes of Health Grant (1R13TR003724-01)

Bronze
MilliporeSigma
SM04.01/SM01.06: Joint Session: Immunoengineering/Nanotechnology
Session Chairs
Nan Ma
Xun Xu
Yoon Yeo
Tuesday PM, April 20, 2021
SM04

8:00 AM - *SM04.01/SM01.06.01
Multifunctional Nanocarriers for Efficient Cancer Immunotherapy

Yunching Chen1,Shu-Yi Lin2,Kuan-Wei Huang1

National Tsing Hua University1,National Health Research Institutes2

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8:25 AM - *SM04.01/SM01.06.02
Immuno-Engineered Biomaterials Reduce Implant-Related Infections

Bingyun Li1,Shichao Zhang1

West Virginia University School of Medicine1

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8:50 AM - SM04.01/SM01.06.03
Polydopamine Capped Gold Nanoparticles for Double NIR-Stimulated Photodynamic Therapy

Miso Lee1,Mao Wei1,Ju Won Lee1,Jae Keun Park1,Vu Pham-Nguyen1,Wan Ho Cho1,Hyuk Sang Yoo1

Kangwon National University1

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9:05 AM - SM04.01/SM01.06.04
Less (Radiation) is More—Bi2S3 Nanoparticles as Efficient Radiosensitizers for Breast Cancer Cells

Isabel Galain1,Emilia Tejeria1,María Elena Cardoso1,Gustavo Mourglia1,Paula Arbildi1,Mariella Terán1,Maria Perez Barthaburu2,Ivana Aguiar1

Facultad de Química - Universidad de la República1,Centro Universitario Regional del Este - Universidad de la República2

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9:20 AM - SM04.01/SM01.06.05
Nucleic Acid Mediated Reversal of Charge—An Useful Methodology to Prevent the Immunostimulatory Activity of Positively Charged Lipid Nanocarrier

Arindam Dey1,2,Adrien Nougarede1,3,Flora Clément1,2,4,Carole Fournier1,2,Evelyne Marche1,2,Marie Escude1,3,Dorothée Jary1,3,Fabrice Navarro1,3,Patrice Marche1,2

Université Grenoble Alpes1,Research Center, CNRS2,Microfluidic Systems and Bioengineering Lab3,CEA, INSERM, IRIG-BIOMICS4

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9:35 AM - SM04.01/SM01.06.06
Tagging the Cancer Cell Surface for Innate Immune Recognition and Destruction by Bifunctional Multivalent Antibody-Recruiting Polymers

Annemiek Uvyn1,Bas de Waal2,Bert Meijer2,Bruno De Geest1

Ghent University1,Technische Universiteit Eindhoven2

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9:50 AM - SM04.01/SM01.06
Panel Discussion


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SM04.02: Machine Learning for Drug Delivery Design
Session Chairs
Yosi Shamay
Tuesday PM, April 20, 2021
SM04

11:45 AM - *SM04.02.01
Machine Learning-Enabled High-Throughput Virtual Screening for Novel Mitochondrial Membrane Dyes

Andrew Ferguson1,Kirill Shmilovich1,Bernadette Mohr2,Tristan Bereau2

The University of Chicago1,University of Amsterdam2

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12:10 PM - *SM04.02.02
Development of Kinase Inhibitor Nanomedicines for Intracranial Tumor Delivery

Daniel Heller1,2,Daniel Tylawsky2,Yosi Shamay3,Kiroto Kiguchi4

Memorial Sloan Kettering Cancer Center1,Weill Cornell Medicine2,Technion–Israel Institute of Technology3,Children’s Hospital of Philadelphia4

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12:35 PM - SM04.02.03
Micro-Nozzle Integration for Controlled Drug Delivery via a Microfluidic Imaging Window

Tristen Head1,2,Natalya Tokranova1,Nathaniel Cady1

State University of New York Polytechnic Institute1,University at Albany, State University of New York2

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12:50 PM - SM04.02.04
Dialysate Regeneration by Efficient Urea Decomposition with TiO2 Nanowire Photoelectrochemical Cell

Guozheng Shao1,Yushi Zang1,Bruce Hinds1

University of Washington1

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1:05 PM - SM04.02.05
Late News: Filamentous Self-Assembly Based on Lithocholic Acid-Polyethyleneimine Conjugate for Local Delivery of Drug and Gene Therapeutics

Jianping Wang1,Fanfei Meng1,Yoon Yeo1

Purdue University1

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1:20 PM - *SM04.02.07
Improving RNA Delivery by Testing Thousands of Nanoparticles In Vivo

James Dahlman1

Georgia Institute of Technology1

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SM04.03: Biomaterials and Drug Delivery for Immunotherapy I
Session Chairs
John Wilson
Yoon Yeo
Tuesday PM, April 20, 2021
SM04

2:15 PM - *SM04.03.01
Engineering Innate Immune Activation with Amphiphillic Biomaterials

Bruno De Geest1

Ghent University1

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2:40 PM - *SM04.03.02
Engineering Approaches to Modulate the Immune System

James Moon1

University of Michigan–Ann Arbor1

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3:05 PM - SM04.03.03
Late News: Poly(ethylene glycol)-b-poly(D,L-lactide) Nanoparticles as Potential Carriers for Anticancer Drug Oxaliplatin

Nikita Sedush1,Yulia Kadina1,Ekaterina Razuvaeva1,Dmitry Streltsov1,Alevtina Kulebyakina1,Alexander Puchkov1,Alexey Nazarov2,Sergei Chvalun1,3

National Research Center Kurchatov Institute1,Department of Chemistry, Lomonosov Moscow State University2,Enikolopov Institute of Synthetic Polymeric Materials Russian Academy of Sciences3

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3:20 PM - SM04.03.04
Donor-Acceptor Based Photothermal Nanoparticles for Augmenting Oxaliplatin Chemotherapy Against Colorectal Cancer

Santu Sarkar1,Nicole Levi1

Wake Forest University School of Medicine1

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3:35 PM - SM04.03.05
Late News: Polymersome Encapsulation of a Lipophilic Protein-Protein Interaction Inhibitor to Achieve Increased Solubility and Therapeutic Index

Yu Tian1,Mathew Schnorenberg1,James LaBelle1,Matthew Tirrell1

The University of Chicago1

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3:50 PM - SM04.03.06
Late News: Activatable Perfluorocarbon Bubble Inflation and Drug Release Using Superheated Perfluorocarbon Nanodroplets

Caroline de Gracia Lux1,Jacques Lux1,Robert Mattrey1

University of Texas Southwestern Medical Center1

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4:05 PM - SM04.03
Panel Discussion


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SM04.04: Biomaterials and Drug Delivery for Immunotherapy II
Session Chairs
Ciana Lopez
Patrick Stayton
Yoon Yeo
Tuesday PM, April 20, 2021
SM04

5:15 PM - *SM04.04.02
Programming Immunity with Smart Materials

John Wilson1

Vanderbilt University1

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5:40 PM - SM04.04.03
A Novel Upconversion Nano Platform for NIR Triggered Drug Release and PDT Therapy

Lei Ma1,Olivia Fernandez1,Hao Zhang2,Lu Li2,Luis Echegoyen1,Xiujun Li1

The University of Texas at El Paso1,Shandong Normal University2

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5:55 PM - SM04.04.04
Polymeric Microcapsules Designed for On-Demand Local Heating and Drug Release in Synergistic Chemo-Photothermal Therapy

Ji-Won Kim1,Sang Hoon Han1,Shin-Hyun Kim1

Korea Advanced Institute of Science and Technology (KAIST)1

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6:10 PM - *SM04.04.05
Cancer Immunotherapy Using Nanomaterial-Based Delivery Systems of Oncolytic Adenovirus

Chae-Ok Yun1

Hanyang University1

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6:35 PM - *SM04.04.01
Modulating the Immune System with Nanostructured Biomaterials

Tejal Desai1

University of California, San Francisco1

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7:00 PM - SM04.04
Panel Discussion


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SM04.05: Advances in Nanomedicine
Session Chairs
Wenguang Liu
Youqing Shen
Wednesday AM, April 21, 2021
SM04

9:00 PM - *SM04.05.01
Biomolecule-Based Nanostructures for Tumor Microenvironment Targeting and Regulation

Guangjun Nie1

National Center for Nanoscience and Technology1

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9:25 PM - *SM04.05.02
Engineering Nano-Based Neurotherapeutics for Pediatric Brain Disease

Elizabeth Nance1

University of Washington1

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9:50 PM - SM04.05.04
Polymeric Micelles for Delivery of Gasotransmitter Hydrogen Sulfide with Proangiogenic Activitiy

Urara Hasegawa1,Andre van der Vlies1

The Pennsylvania State University1

Show Abstract

10:05 PM - *SM04.05.05
Theragnosis Inspired by Real-Time Molecular Imaging

Ick Chan Kwon1

Harvard Medical School1

Show Abstract

10:30 PM - SM04.05
Panel Discussion


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2021-04-21   Show All Abstracts

Symposium Organizers

Yoon Yeo, Purdue University
Yosi Shamay, Technion-Israel Institute of Technology
Youqing Shen, Zhejiang University
Patrick Stayton, University of Washington

Symposium Support

Gold
National Institutes of Health
National Center for Advancing Translational Sciences of the National Institutes of Health Grant (1R13TR003724-01)

Bronze
MilliporeSigma
SM04.06: Gene Delivery I
Session Chairs
Youqing Shen
Yoon Yeo
Wednesday AM, April 21, 2021
SM04

8:00 AM - *SM04.06.01
The Direction of Nucleic Acid Drug Delivery—From RNA Interference to Genome Editing

Jun Wang1,2

South China University of Technology, Guangzhou International Campus1,South China University of Technology2

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8:25 AM - *SM04.06.02
Polyplexes for Local Delivery of siRNA.

Tina Vermonden1,Lies Fliervoet1,Cristina Casadidio1

Utrecht University1

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8:50 AM - SM04.06.03
Nucleic Acid Co-Delivery—How to Modulate Protein Co-Expression by Formulation of Payload

Hanieh Moradian1,2,3,Andreas Lendlein1,2,3,Manfred Gossen1,2

Helmholtz-Zentrum Geesthacht1,Berlin-Brandenburg Center for Regenerative Therapies (BCRT)2,University of Potsdam3

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9:05 AM - SM04.06.04
Antibacterial Activities of Cationic Porphyrins and Gold Nanorod Encapsulated Porphyrins and Their Activities on Bacterial Cell Lines

Nthabeleng Hlapisi1

University of Zululand1

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9:20 AM - *SM04.06.05
PNAGA-based Hydrogels for Diverse Biomedical Applications

Wenguang Liu1,Chunyan Cui1,Chuanchuan Fan1

Tianjin University1

Show Abstract

9:45 AM - SM04.06
Panel Discussion


Show Abstract

SM04.07: Gene Delivery II
Session Chairs
Yosi Shamay
Wednesday PM, April 21, 2021
SM04

11:45 AM - *SM04.07.01
RNA Therapeutics Using Targeted Lipid Nanoparticles—From Gene Silencing to Gene Editing

Dan Peer1

Tel Aviv University1

Show Abstract

12:10 PM - *SM04.07.02
RNA Delivery

Manfred Gossen1

Helmholtz-Zentrum Geesthacht1

Show Abstract

12:35 PM - SM04.07.03
Late News: Effect of Nucleotide Chemistry on Expression of In Vitro Transcribed mRNA

Hanieh Moradian1,2,3,Andreas Lendlein1,2,3,Manfred Gossen1,2

Helmholtz-Zentrum Geesthacht, Institute of Active Polymers1,Berlin-Brandenburg Center for Regenerative Therapies (BCRT)2,Institute of Biochemistry and Biology, University of Potsdam3

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12:50 PM - SM04.07.04
Competitive Binding and Molecular Crowding Regulate the Cytoplasmic Interactome of Non-Viral Polymeric Gene Delivery Vectors

Julien Gautrot1,Alex Raynold1,Danyang Li1,Fengjin Qu1

Queen Mary, University of London1

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1:05 PM - SM04.07.05
Cell Nucleus Decoration with Oxidized Nano-Graphene—A New Opportunity in Drug Delivery

Martina Mugnano1,Giuseppe Cesare Lama2,Rachele Castaldo2,Francesco Merola1,Gennaro Gentile2,Veronica Ambrogi3,Piero Cerruti2,Pasquale Memmolo1,Vito Pagliarulo1,Pietro Ferraro1,Simonetta Grilli1

Institute of Applied Science & Intelligent Systems ‘E. Caianiello’, National Council of Research of Italy (ISASI-CNR)1,Institute for Polymers, Composites and Biomaterials, National Council of Research of Italy (IPCB-CNR)2,University of Naples Federico II3

Show Abstract

1:20 PM - SM04.07
Panel Discussion


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SM04.08: Biomaterials and Bioinspired Materials I
Session Chairs
Kim Woodrow
Yoon Yeo
Wednesday PM, April 21, 2021
SM04

2:15 PM - *SM04.08.01
Developing Therapeutic Materials to Redirect Cellular Chatter

Juliane Nguyen1

University of North Carolina at Chapel Hill1

Show Abstract

2:40 PM - *SM04.08.02
Nanoscale Metal-Organic Frameworks for Chemoradiation and Radioluminescent Imaging

Conroy Sun1,2,Megan Neufeld1,Allison DuRoss1,Madeleine Landry1

Oregon State University1,Oregon Health & Science University2

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3:05 PM - SM04.08.03
Late News: 3D Printing of Spatiotemporally Controlled Drug Delivery Dental Device

Valentine Berger1,Zhi Luo1,Jean-Christophe Leroux1

ETH Zurich1

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3:20 PM - SM04.08.05
Late News: Dissecting How Cells Internalize and Process Nano-Sized Drug Carriers for Nanomedicine Applications

Anna Salvati1

University of Groningen1

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3:35 PM - SM04.08.06
Late News: Controlling Porosity and Protein Release Profile of Nanofibrillar Chitosan Scaffolds

Christine Jerome1,Muhammad Haji Mansor1,2,Jean-Michel Thomassin1,Alain Colige1,Emmanuel Garcion2,Frank Boury2

Univ de Liege1,Université d'Angers2

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3:50 PM - SM04.08
Panel Discussion


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SM04.09: Biomaterials and Bioinspired Materials II
Session Chairs
Ciana Lopez
Patrick Stayton
Wednesday PM, April 21, 2021
SM04

5:15 PM - *SM04.09.01
Long-Acting Parenteral Products for Global Health—Challenges and Opportunities

Dennis Lee1,2

Bill & Melinda Gates Foundation1,Global Health2

Show Abstract

5:40 PM - *SM04.09.02
In Situ 3D-Patterning of Electrospun Fibers Using Two-Layer Composite Materials

Kim Woodrow1

University of Washington1

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6:05 PM - SM04.09.03
Malleable Hydrogel Containing Micellar Cargo-Expellers for Prompt Transdermal Patch

Sung-Ho Shin1,2,Youngho Eom3,Eun Seong Lee4,Sung Yeon Hwang1,5,Dongyeop Oh1,5,Jeyoung Park1,5

Korea Research Institute of Chemical Technology1,Purdue University2,Pukyong National University3,The Catholic University of Korea4,University of Science and Technology5

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6:20 PM - SM04.09.04
Late News: A Platform for Macrophage-Mediated Delivery of Polymeric Prodrugs to Solid Tumors

Ciana Lopez1,2,Katherine Brempelis2,James Matthaei2,Kate Montgomery1,Selvi Srinivasan1,Debashish Roy1,Shannon Kreuser2,John Chiefari3,Courtney Crane2,Patrick Stayton1

University of Washington1,Seattle Children's Research Institute2,CSIRO Manufacturing3

Show Abstract

6:35 PM - *SM04.09.05
Boosting Intracellular Delivery of Messenger RNA

Gaurav Sahay1

Oregon State University1

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7:00 PM - SM04.09
Panel Discussion


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