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Call for Papers

Symposium SM5—Aqueous Cytomimetic Materials

A wide variety of living materials consist mainly of aqueous solutions containing different solutes and macromolecules. The assembly of building blocks in aqueous environments results in small units, such as membraneless organelles, as well as large biological tissues and organs. Nature has demonstrated the power to synthesize, fabricate and construct complicated functional materials in mild aqueous and isothermal conditions, in a way that materials scientists and engineers have yet to achieve. For instance, membraneless organelles can be formed in aqueous solutions. Complicated membranes can be assembled from lipids and proteins, achieving excellent control over the transport of molecules into and out of biological cells A more comprehensive understanding of the science and mechanisms behind these processes will inspire cytomimetic approaches to synthesize new materials, creating opportunities to engineer more complex hierarchical structures.

The exploration into aqueous cytomimetic strategies may start with investigations into the physical processes, such as aqueous phase separation, that are essential for forming relatively simple organelles in biological systems. Aqueous two-phase systems (ATPS) have already demonstrated promises in enabling fabrication of new bio-materials and development of useful biotechnological techniques. The unique properties of the systems resulting from aqueous phase separation often demand new characterization tools. New cytomimetic chemical synthesis can be facilitated with good knowledge of the fluid dynamics and interfacial phenomena underlying the aqueous environments. Modern micro-engineering and microfluidic devices are also playing an increasingly important role in unraveling the mysteries behind aqueous cytomimetic systems and in controlling the assembly of building blocks, such as lipids and proteins in aqueous environments. This symposium will bring together researchers from different relevant disciplines and cover the complete range of topics including fundamentals, characterization, and applications.

Interdisciplinary and multidisciplinary topics related to chemistry, physics, biomedical engineering, materials science and engineering will be organized into different sessions of invited abstracts. Therefore, participants can interact with experts from different areas to explore new avenues relevant to aqueous cytomimetic materials. In the closing session, the abstracts will focus on discussions as to how different disciplines can be integrated together for furthering the applications of aqueous cytomimetic materials.

Topics will include:

  • Bio-materials enabled by aqueous two-phase systems
  • Cytomimetic chemistry for materials synthesis
  • Theory and modeling of phase separation in biological systems
  • Fundamentals underlying properties of aqueous phase separation and aqueous two-phase systems
  • Applications of aqueous two-phase systems and aqueous emulsions (e.g. biotechnology)

Invited Speakers:

  • Clifford Brangwynne (Princeton University, USA)
  • Rivas Caballero (Consejo Superior de Investigaciones Científicas (CSIC), Spain)
  • Chun-Long Chen (Pacific Northwest National Laboratory, USA)
  • Patrick Collier (Oak Ridge National Laboratory, USA)
  • Maria Olvera de la Cruz (Northwestern University, USA)
  • Rumiana Dimova (Max Planck Institute of Colloids and Interfaces, Germany)
  • John Frampton (Dalhousie University, Canada)
  • Gregory Jedd (Temasek Lifesciences Laboratory, Singapore)
  • Daniel Kamei (University of California, Los Angeles, USA)
  • Tuomas Knowles (Cambridge University, United Kingdom)
  • Istvan Lagzi (Budapest University of Technology and Economics, Hungary)
  • Yuichiro Nagatsu (Tokyo University of Agriculture and Technology, Japan)
  • Sarah Perry (University of Massachusetts, USA)
  • Joseph Schlenoff (Florida State University, USA)
  • Kathleen Stebe (University of Pennsylvania, USA)
  • Hossein Tavana (University of Akron, USA)
  • Scott Tsai (Ryerson University, Canada)
  • Kanta Tsumoto (Mie University, Japan)
  • Takuya Ueda (University of Tokyo, Japan)
  • Hiroshi Umakoshi (Osaka University, Japan)
  • Boris Zaslavsky (Cleveland Diagnostics, USA)

Symposium Organizers

Anderson H.C. Shum
The University of Hong Kong
Department of Mechanical Engineering
Hong Kong
852-28597904, ashum@hku.hk

Takahiko Ban
Osaka University
Graduate School of Engineering Science, Division of Chemical Engineering

Christine Keating
The Pennsylvania State University
Department of Chemistry
814-863-7832, keating@chem.psu.edu

Shuichi Takayama
University of Michigan
Department of Biomedical Engineering
734-615-5539, takayama@umich.edu