2019 MRS Spring Meeting & Exhibit

Symposium SM05: Supramolecular Biomaterials for Regenerative Medicine and Drug Delivery

2019-04-23   Show All Abstracts

Symposium Organizers

Matthew Webber, University of Notre Dame
Eric Appel, Stanford University
Honggang Cui, Johns Hopkins University
Patricia Dankers, Technische Universiteit Eindhoven

Symposium Support

CEM Corporation
MilliporeSigma
3M
SM05.01: Supramolecular Peptide Assemblies I
Session Chairs
Eric Appel
Honggang Cui
Tuesday AM, April 23, 2019
PCC North, 200 Level, Room 227 C

10:30 AM - SM05.01.01
Metabolite-Responsive Peptide Nanostructures

Rein Ulijn1,2

City University of New York1,Hunter College2

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11:00 AM - SM05.01.02
Nucleopeptide Assemblies Selectively Sequester ATP in Cancer Cells and Target Cell Nucleolus

Huaimin Wang1,Bing Xu1

Brandeis University1

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11:15 AM - SM05.01.03
STINGel—A Biomaterial-Based Drug Delivery Vehicle for Enhanced Cancer Immunotherapy

David Leach1,Jeffrey Hartgerink1,Neeraja Dharmaraj2,Simon Young2

Rice University1,University of Texas Health Science Center at Houston2

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11:30 AM - SM05.01.04
Self-Assembling MultiDomain Peptide Nanofibers for Immunotherapy, Wound Healing and Other Biomedical Applications

Jeffrey Hartgerink1

Rice University1

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SM05.02: Supramolecular Peptide Assemblies II
Session Chairs
Patricia Dankers
Matthew Webber
Tuesday PM, April 23, 2019
PCC North, 200 Level, Room 227 C

1:30 PM - SM05.02.01
Supramolecular Peptide Immunotherapies—Effect of Material Structure on Immune Phenotype

Joel Collier1,Yaoying Wu1,Sean Kelly1,Lucas Shores1

Duke University1

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2:00 PM - SM05.02.02
Molecular Mechanism of Alzheimer's Disease—Towards Prevention and Cure

Zoya Leonenko1

University of Waterloo1

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2:15 PM - SM05.02.03
Multidomain Peptide Hydrogel Accelerates Healing of Full-Thickness Wounds in Diabetic Mice

Nicole Carrejo1,Amanda Moore1,Tania Lopéz Silva1,David Leach1,I-Che Li1,Douglas Walker1,Jeffrey Hartgerink1

Rice University1

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2:30 PM - SM05.02.04
Supramolecular Peptide Nanotechnology for Antimicrobial Therapies

Helena Azevedo1

Queen Mary University of London1

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3:00 PM -
BREAK


3:30 PM - SM05.02.05
Intracellular Delivery of Therapeutic Peptides Using Cleavable Peptide Amphiphiles

Matthew Tirrell1,Mathew Schnorenberg1,Handan Acar1,Logan Leak1,Sang Pil Yoo1,James LaBelle1

University of Chicago1

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4:00 PM - SM05.02.06
Self-Assembling Prodrugs

Honggang Cui1

Johns Hopkins University1

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4:15 PM - SM05.02.07
Programmed Cell Death Instructed by Membrane-Interacting Supramolecular Assemblies

Shantanu Sur1,Samuel Stupp2,Charlotte Chen2,Darren Sipes1,Arielle Stoian1

Clarkson University1,Northwestern University2

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4:30 PM - SM05.02.08
Instructed-Assembly for Cell Morphogenesis and Mitochondrial Delivery

Bing Xu1,Huaimin Wang1,Hongjian He1,Zhaoqianqi Feng1

Brandeis University1

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SM05.03: Poster Session: Supramolecular Biomaterials for Regenerative Medicine and Drug Delivery
Session Chairs
Eric Appel
Honggang Cui
Patricia Dankers
Matthew Webber
Tuesday PM, April 23, 2019
PCC North, 300 Level, Exhibit Hall C-E

5:00 PM - SM05.03.01
A Lipid Raft Modified Multifunctional Nano Gene Delivery System in Brain Targeting

Xia Cao1,2,Wei Wang1,Jianping Wang1,Qilong Wang1,Ximing Xu1,Jiangnan Yu1

Jiangsu University1,Harvard medical school2

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5:00 PM - SM05.03.02
Coassembly of Enantiomeric Peptides Inside Mitochondria for Cancer Therapy

Ja-Hyoung Ryu1

UNIST1

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5:00 PM - SM05.03.03
Receptor-Targeting Protein Nanocarriers for Potential Chemotherapy of Non-Muscle-Invasive Bladder Cancer

Koon Gee Neoh1,Jing Zhang1,Mullapudi Sneha Sree1,Juwita Rahmat1,Ratha Mahendran1,En-Tang Kang1,Edmund Chiong1

National University of Singapore1

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5:00 PM - SM05.03.04
Polymer Nanoparticle-Based Combination Therapy for the Treatment of Multi-Drug Resistant Bacteria and Biofilm Infections

Akash Gupta1,Jessa Makabenta1,Cheng-Hsuan Li1,Ryan Landis1,Friederike Schlüter1,Vincent Rotello1

University of Massachusetts Amherst1

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5:00 PM - SM05.03.05
Spatially Controlled Bioorthogonal Catalysis for Imaging and Drug Delivery

Riddha Das1,Akash Gupta1,Ryan Landis1,Gulen Tonga1,Vincent Rotello1

University of Massachusetts Amherst1

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5:00 PM - SM05.03.06
Nerve/Osteoblast/Endothelium Multicellular System Based on Ultralong Hydroxyapatite Nanowires/Cellulose Multifunctional Biological Paper Promotes Bone Regeneration

Feng Liu1

Shandong University1

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5:00 PM - SM05.03.07
Jet Printing Organic Cocrystals from the Vapor Phase

Siddharth Borsadia1,Max Shtein1

University of Michigan1

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5:00 PM - SM05.03.08
Encapsulation of Flavonoids and Triterpenoids Extracted from Cranberries in Peptide-Based Spheres

Yasaman Hamedani1,Catherine Neto1,Milana Vasudev1

University of Massachusetts Dartmouth1

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5:00 PM - SM05.03.09
Fluorophilic-Lipophilic-Hydrophilic Poly-2-Oxazolines Block Copolymers as MRI Contrast Agents—From Synthesis to Self-Assembly

Sergey Filippov1,2,Leonid Kaberov2,Bart Verbraeken3,Richard Hoogenboom3

Harvard University1,Institute of Macromolecular Chemistry2,Ghent University3

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5:00 PM - SM05.03.10
A Bioinspired Platform to Deliver Neurotrophins to the Central Nervous System for Neural Regeneration

Duo Xu1,Yunfeng Lu1

University of California, Los Angeles1

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5:00 PM - SM05.03.11
Supramolecular Polymeric Chemotherapy Based on cucurbit[7]uril-PEG Copolymer

Han Wu1,Hao Chen1,Yueyue Chen2,Jiang-Fei Xu1,Zhiwei Sun2,Xi Zhang1

Tsinghua University1,Capital Medical University2

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5:00 PM - SM05.03.12
pH-Induced Charge-Reversal Amphiphile with Cancer Cell-Selective Membrane-Disrupting Activity

Yincheng Chang1,Jiang-Fei Xu1,Xi Zhang1

Tsinghua University1

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5:00 PM - SM05.03.13
Multifunctional β-Cyclodextrin Macrocrosslinker-Based Self-Healable Hydrogels Showing High Mechanical Strength, Enhanced Stability and pH Responsiveness for Drug Delivery

Seunho Jung1,Daham Jeong1,Chul-gu Kim1,Yohan Kim1,Seonmok Kim1

Konkuk University1

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5:00 PM - SM05.03.14
Agar -Sericin Blend Antioxidant Hydrogel Dressing for Chronic Wounds

Suhela Tyeb1,Nitesh Kumar2,Ashok Kumar1,Vivek Verma2

Indian Institute of Technology Kanpur1,Indian Institure of Technology Kanpur2

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5:00 PM - SM05.03.15
Multi-Functional and Bio-Responsive Electrospun Nanofiber Membranes

Daewoo Han1,Shindu Thomas1,Emily Gay1,Giovanni Pauletti1,Michael Thomas1,Andrew Steckl1

University of Cincinnati1

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5:00 PM - SM05.03.16
Adsorption Kinetics of Methylene Blue in Biocompatible Hydrogels for Drug Delivery Systems

Lucas Ribeiro1,Renata Lang Sala1,Emerson Rodrigues de Camargo1

Federal University of Sao Carlos1

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5:00 PM - SM05.03.17
Mesoporous Nanoparticles for Drug Delivery Applications

Shahjahan Chowdury1,SeungHyun Park2,SungBum Park1,Yong-il Park1,Won Hyung Ryu2

Kumoh National Institute of Technology1,Yonsei University2

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2019-04-24   Show All Abstracts

Symposium Organizers

Matthew Webber, University of Notre Dame
Eric Appel, Stanford University
Honggang Cui, Johns Hopkins University
Patricia Dankers, Technische Universiteit Eindhoven

Symposium Support

CEM Corporation
MilliporeSigma
3M
SM05.04: Supramolecular Engineering
Session Chairs
Honggang Cui
Matthew Webber
Wednesday AM, April 24, 2019
PCC North, 200 Level, Room 227 C

9:15 AM - SM05.04.01
Quantifying Spatial Organization in Functional Biomaterials

Maartje Bastings1

Ecole Polytechnique Federale Lausanne1

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9:45 AM - SM05.04.02
Enabling Long-Term Antibody Delivery with Polymer-Nanoparticle Supramolecular Hydrogels

Anthony Yu1,Gillie Agmon1,Awua Buahin1,Eric Appel1

Stanford University1

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10:00 AM -
BREAK


10:30 AM - SM05.04.03
Supramolecular Biomaterials for Engineering the Cell-Material Interface—From Design to High Throughput Screening

Patricia Dankers1,Ronald van Gaal1,Annika Vrehen1,Simone Hendrikse1,Peter-Paul Fransen1,Mani Diba1

Eindhoven University of Technology1

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10:45 AM - SM05.04.04
Digestion Inspired Supramolecular Drug Delivery Materials

Stefan Salentinig1

University of Fribourg1

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11:00 AM - SM05.04.05
The Design and Application of Dissipative Supramolecular Materials

Job Boekhoven1,Marta Tena-Solsona1,Raphael Grötsch1,Caren Wanzke1,Benedikt Rieß1,Patrick Schwarz1,Fabian Schnitter1

TUM - Chemistry Department1

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11:30 AM - SM05.04.06
Highly Functionalised Water-Soluble Fullerene Derivatives—Cage Size Affects Hierarchical Self-Assembled Structures

Ilija Rasovic1,2,Alba Piacenti2,Sonia Contera2,Kyriakos Porfyrakis2

University of Birmingham1,University of Oxford2

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SM05.05: Macromolecular Therapeutics
Session Chairs
Eric Appel
Patricia Dankers
Wednesday PM, April 24, 2019
PCC North, 200 Level, Room 227 C

1:30 PM - SM05.05.01
Macromolecular Therapeutics

James Hedrick1

IBM Research1

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2:00 PM - SM05.05.02
Design of Dendronized Polypeptides and Dendritic Bolaamphiphiles for siRNA and mRNA Delivery

Zhibin Guan1

University of California, Irvine1

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2:30 PM -
BREAK


SM05.06: Supramolecular Hydrogels
Session Chairs
Eric Appel
Honggang Cui
Wednesday PM, April 24, 2019
PCC North, 200 Level, Room 227 C

3:30 PM - SM05.06.01
Overcoming the Blood-Brain Barrier—Post-Resection Drug Delivery to Glioblastoma Multiforme Using Supramolecular Hydrogels

Oren Scherman1

University of Cambridge1

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4:00 PM - SM05.06.02
Dynamic and Responsive Supramolecualr Biomaterials

Matthew Webber1

University of Notre Dame1

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4:15 PM - SM05.06.03
Bio-Inspired Metal-Coordination Crosslinking—Easy Access to Broad Dynamics When Engineering Polymer Gel Mechanics

Niels Holten-Andersen1

Massachusetts Institute of Technology1

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4:45 PM - SM05.06.04
Hydrogel Using Cyclic Oligosaccharide-Based Supramolecular Complex System for Hydrophobic Drug Delivery to Enhance the Mechanical Strength, pH Responsiveness, Drug Loading Capacity and Self-Healing Property

Daham Jeong1,Chul-gu Kim1,Seunho Jung1

Konkuk Univeristy1

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2019-04-25   Show All Abstracts

Symposium Organizers

Matthew Webber, University of Notre Dame
Eric Appel, Stanford University
Honggang Cui, Johns Hopkins University
Patricia Dankers, Technische Universiteit Eindhoven

Symposium Support

CEM Corporation
MilliporeSigma
3M
SM05.07: Supramolecular Regenerative Medicine
Session Chairs
Patricia Dankers
Matthew Webber
Thursday AM, April 25, 2019
PCC North, 200 Level, Room 227 C

9:00 AM - SM05.07.01
Multi-Functional Supramolecular Hydrogels for Heart Regenerative Drug Release

Maaike Schotman1,Maarten Bakker1,Peter-Paul Fransen1,Steven Chamuleau2,Patricia Dankers1

Eindhoven University of Technology1,University Medical Center Utrecht2

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9:15 AM - SM05.07.02
Supra-Molecular Hydrogels as Custom Bioinks

Sarah Heilshorn1

Stanford University1

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9:45 AM -
BREAK


10:15 AM - SM05.07.03
Materials Science for Regenerative Biology

Samuel Stupp1

Northwestern University1

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10:45 AM - SM05.07.04
Kidney Organoid Encapsulation in Static vs Dynamic Cross-Linked Supramolecular Hydrogels for Organoid Growth

Floor Ruiter1,Thomas Geuens1,Shahzad Hafeez1,Antonio Feliciano1,Clemens van Blitterswijk1,Vanessa LaPointe1,Matthew Baker1

Maastricht University1

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11:00 AM - SM05.07.05
Covalent-Supramolecular Polymer Hybrids for Cartilage Repair

Jacob Lewis1,Mark McClendon1,Brett Nemke2,Yan Lu2,Mark Markel2,Samuel Stupp1

Northwestern University1,University of Wisconsin–Madison2

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11:15 AM - SM05.07.06
Evaluating and Designing BTA Supramolecular Hydrogels for Viscoelastic 3D Cell Culture

Shahzad Hafeez1,Nicholas Matsumoto2,René Lafleur2,Egbert Meijer2,Matthew Baker1

Maastricht University1,Institute of Complex Molecular Systems (ICMS), Eindhoven University of Technology, Eindhoven, Te Netherlandsh2

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11:30 AM - SM05.07.07
From Dynamically Crosslinked Hydrogels to Tunable Bioinks for 3D-Printed Tissue Engineering Constructs

Matthew Baker1

Maastricht University1

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