3D Printing for Medical Applications

3D printing, also known as additive manufacturing and solid freeform fabrication, is an approach involving additive layer-by-layer fabrication of a three-dimensional structure through selective joining of material; processing of the structure is directed by a computer-aided design (CAD) model. Unlike conventional methods, 3D printing techniques may enable the development of structures with well-defined small-scale features and multiple functions. This MRS/SFB joint webinar aims to address recent 3D printing for medical applications with a focus on recent advances in biomaterials for 3D printing and recent efforts to translate 3D printing technology. In particular, efforts to characterize 3D printed materials via in vitro and in vivo methods will also be considered. The processing of radiographic images and the development of computer models will also be discussed. We anticipate that this workshop will facilitate future research activities, including industry-university collaborations, involving 3D printing of biomaterials for use in medicine, surgery, and dentistry.
    

Program

• Scaffold-guided Tissue Engineering from Bench to Bedside
  Dietmar W. Hutmacher, Queensland University of Technology
   
  
• dECM Bioinks for Engineering Tissue and Organ Specific Microenvironment
  Jinah Jang, Pohang University of Science and Technology
    
• Bioprinting for Translational Applications
  James Yoo, Wake Forest Institute for Regenerative Medicine
    
• A Design Control Paradigm for Clinical Application of 3D Printed Patient Specific Scaffolds
  Scott Hollister, Georgia Institute of Technology
  

Moderator

Roger Narayan, North Carolina State University

Roger Narayan is a distinguished professor in the Joint Department of Biomedical Engineering at the University of North Carolina and North Carolina State University. He currently serves as an editorial board member for several academic journals, including as associate editor of Applied Physics Reviews. Narayan has edited several books, including the textbook Biomedical Materials, Second Edition, the handbook Materials for Medical Devices, and the Encyclopedia of Biomedical Engineering. He has previously served as director of the TMS Functional Materials Division, the ASM International Emerging Technologies Awareness Committee, and the American Ceramic Society Bioceramics Division. As the 2016-2017 ASME Swanson Fellow, Narayan worked with America Makes on several activities to disseminate additive manufacturing technology, including the development of a workforce/education/outreach roadmap for additive manufacturing, and the development of a repository containing educational materials related to additive manufacturing. Narayan has received several honors, including the NCSU Alcoa Foundation Engineering Research Achievement Award, the University of North Carolina Jefferson-Pilot Fellowship in Academic Medicine, the National Science Faculty Early Career Development Award, the Office of Naval Research Young Investigator Award, and the American Ceramic Society Richard M. Fulrath Award. He has been elected as Fellow of AAAS, ASME, ASM International, AIMBE, and American Ceramic Society.

Speakers

Dietmar W. Hutmacher, Queensland University of Technology

Dietmar Hutmacher is a biomedical engineer, educator, inventor, and creator of new intellectual property opportunities. He is committed to fostering transformative research and pedagogical innovation as well as programs that create an entrepreneurial mindset amongst faculty and students. He directs the Centre for Regenerative Medicine and the ARC Training Centre in Additive Biomanufacturing at QUT, an interdisciplinary team of researchers including engineers, cell biologists, polymer chemists, clinicians, and veterinary surgeons. Hutmacher is an internationally recognized leader in the fields of biomaterials, tissue engineering and regenerative medicine with expertise in commercialization. He has translated a bone tissue engineering concept from the laboratory through to clinical application involving in vitro experiments, preclinical studies and ultimately clinical trials. His recent research efforts have resulted in traditional scientific/academic outputs as well as pivotal commercialization outcomes. His pre-eminent international standing and impact on the field are illustrated by fact that he is listed as a highly cited researcher.

Jinah Jang, Pohang University of Science and Technology

Jinah Jang received her PhD degree at Pohang University of Science and Technology (POSTECH), and trained as postdoctoral fellow in POSTECH and Institute for Stem Cell and Regenerative Medicine at University of Washington. She joined the POSTECH in 2017 and is an associate professor in the Convergence IT Engineering, Mechanical Engineering, and School of Interdisciplinary Bioscience and Bioengineering. Jang has published more than 70 peer-reviewed articles in journals including Chemical Reviews, Science Advances, Nature Communications, and Biomaterials. She serves as an Editorial Board Member of the International Journal of Molecular Science, Applied Sciences, and Journal of Korean Society for Precision Engineering and as the Associate Editor of Essays in Biochemistry. She has served as a board member of multiple academic societies including Early Career Researchers Committee of International Society for Biofabrication, and the Korean Society for Precision Engineering. Jang has received numerous awards including the ISBF young scientist award (2014), Presidential Postdoc Fellowship from NRF Korea (2015), Excellence Young Researcher Award from Korea Society for Biomaterials (2020) and Korea Tissue Engineering and Regenerative Medicine Society (2021). Her research interest lies in engineering the functional human tissues using high-performance stem cells and printable biomaterials-based 3D bioprinting technology.

James Yoo is Professor and Associate Director of the Wake Forest Institute for Regenerative Medicine (WFIRM), with a cross-appointment to the Departments of Urology, Physiology and Pharmacology, and the Virginia Tech-Wake Forest School of Biomedical Engineering and Sciences. Yoo's research efforts have been directed toward the clinical translation of tissue engineering technologies and cell-based therapies. His background in cell biology and medicine has facilitated the transfer of several cell-based technologies from the bench-top to the bedside. A few notable examples of successful clinical translation include the bladder, urethra, vagina, and muscle cell therapy for incontinence. Yoo has been a lead scientist in the bioprinting program at WFIRM and was instrumental in developing skin bioprinting and integrated tissue and organ printing (ITOP) systems for preclinical and clinical applications.