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Fall 2008 Logo2008 MRS Fall Meeting & Exhibit

December 1-5, 2008 | Boston
Meeting Chairs:
 S. Ashok, Shenda M. Baker, Michael R. Fitzsimmons, Young-Chang Joo

Symposium HH : Advances in Material Design for Regenerative Medicine, Drug Delivery, and Targeting/Imaging

2008-12-01   Show All Abstracts

Symposium Organizers

V. Prasad Shastri Vanderbilt University
Andreas Lendlein Institute of Polymer Research
LinShu Liu U. S. Dept of Agriculture
Samir Mitragotri University of California-Santa Barbara
Antonios Mikos Rice University
HH1: Advanced Biomaterials I
Session Chairs
Andreas Lendlein
Monday PM, December 01, 2008
Room 310 (Hynes)

9:00 AM - **HH1.1
Citric Acid-based Biomaterials: Teaching an Old Compound New Tricks.

Guillermo Ameer 1
1 Department of Biomedical Engineering and the Department of Surgery, Northwestern University, Evanston, Illinois, United States

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9:30 AM - HH1.2
Dual and Triple Shape Capability of Poly(ε-caprolatone)dimethacrylate Networks with Dangling PEG Chains.

Marc Behl 1 , Ingo Bellin 1 , Andreas Lendlein 1
1 Center for Biomaterial Development, Institute of Polymer Research, GKSS Forschungszentrum Geesthacht GmbH, Teltow Germany

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9:45 AM - HH1.3
Fluorescent Core-Shell Silica Nanoparticles as Probes for in Vitro and in Vivo Imaging and Sensing.

Andrew Burns 1 , Erik Herz 1 , Barbara Baird 2 , Jin Hyang Choi 3 , Gabriela Hidalgo 4 , Alexander Nikitin 3 , Len Lion 4 , Anthony Hay 5 , Michelle Bradbury 6 , Ulrich Wiesner 1
1 Materials Science & Engineering, Cornell University, Ithaca, New York, United States, 2 Chemistry & Chemical Biology, Cornell University, Ithaca, New York, United States, 3 Biomedical Science, Cornell University, Ithaca, New York, United States, 4 Civil & Environmental Engineering, Cornell University, Ithaca, New York, United States, 5 Microbiology, Cornell University, Ithaca, New York, United States, 6 Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York, United States

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10:00 AM - HH1.4
Optimised Synthetic Route for Tuneable Shell SiO2@Fe3O4 Core-Shell Nanoparticles.

Carmen Vogt 1 , Muhammet Toprak 1 , Jingwhen Shi 2 , Bengt Fadeel 2 , Stefan Brene 3 , Rouslan Sitnikov 3 , Mamoun Muhammed 1
1 Functional Materials, Royal Institute of Technology, Stockholm Sweden, 2 Institute of Environmental Medicine, Karolinska Institutet, Stockholm Sweden, 3 Experimental MR Center, Karolinska Institutet, Stockholm Sweden

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10:15 AM - HH1.5
Antimicrobial Nanostructured Hydrogel Webs with Controlled Silver Release.

Jian Wu 1 , Shuyu Hou 1 , Dacheng Ren 1 , Patrick Mather 1
1 Department of Biomedical and Chemical Engineering and Syracuse Biomaterials Institute, Syracuse University, Syracuse, New York, United States

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10:30 AM - HH1.6
Engineering Biomimetic Polymersomes for Effective Cytosolic Delivery.

Giuseppe Battaglia 1
1 Engineering Materials, University of Sheffield, Sheffield United Kingdom

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10:45 AM - HH1.7
Single Component Polymer Capsules for Biomedical Applications.

Alexander Zelikin 1 , Siow Feng Chong 1 , Sri Sivakumar 1 , Amy Sexton 2 , Robert De Rose 2 , Stephen Kent 2 , Remy Robert 3 , Kim Wark 3 , Frank Caruso 1
1 Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria, Australia, 2 Department of Microbiology and Immunology , The University of Melbourne, Parkville, Victoria, Australia, 3 Preventative Health Flagship and Division of Molecular and Health Technologies, CSIRO, Parkville, Victoria, Australia

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11:00 AM - HH1: ADBIOMAT
BREAK

HH2: Drug Delivery Systems I
Session Chairs
Samir Mitragotri
Monday PM, December 01, 2008
Room 310 (Hynes)

11:30 AM - HH2.1
Micelles for Delivery of Nitric Oxide.

Yun Suk Jo 1 , Jay Gantz 1 , André van der Vlies 1 , Tyler Thacher 1 , Sasa Antonijevic 2 3 4 , Simone Cavadini 2 , Davide Demurtas 5 , Nikolaos Stergiopulos 1 , Jeffrey Hubbell 1 2
1 Institute of Bioengineering (IBI), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne Switzerland, 2 Institute of Chemical Sciences and Engineering (ISIC), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne Switzerland, 3 Department of Chemistry, University of California Berkeley, Berkeley, California, United States, 4 Division of Materials Science, Lawrence Berkeley National Laboratory, Berkeley, California, United States, 5 Centre Intégratif de Génomique, Université de Lausanne, Lausanne Switzerland

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11:45 AM - HH2.2
Triterpene Saponin Glycosides: a New Class of Chemical Penetration Enhancers.

Christopher Pino 1 , Jordan Gutterman 2 , V. Shastri 1
1 Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, United States, 2 Department of Molecular Therapeutics, M.D. Anderson Cancer Center, Houston, Texas, United States

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12:00 PM - HH2.3
Structure and Mechanical Properties of Nucleic Acid Lipid Films and Their Application as Drug Delivery Vehicles Towards Human Breast Cancer Cells.

Surekha Gajria 1 2 , Thorsten Neumann 2 1 , Matthew Black 3 2 , Wirasak Smitthipong 2 3 , Luc Jaeger 1 2 , Matthew Tirrell 3 2
1 Chemistry, UC Santa Barbara, Santa Barbara, California, United States, 2 Materials Research Laboratory, UC Santa Barbara, Santa Barbara, California, United States, 3 College of Engineering, UC Santa Barbara, Santa Barbara, California, United States

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12:15 PM - HH2.4
IMAC Surface Modification of Polyketal Microparticles for Dual-Mode Drug Release.

Jay Sy 1 , Niren Murthy 1 2 , Michael Davis 1 3
1 Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, Atlanta, Georgia, United States, 2 Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia, United States, 3 Division of Cardiology, Emory School of Medicine, Atlanta, Georgia, United States

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12:30 PM - HH2.5
Nanoparticles of Porous Iron Carboxylates as New Drug Carriers.

Patricia Horcajada 1 , Christian Serre 1 , Ruxandra Gref 2 , Tamim Chalati 2 , Gerard Ferey 1 , Patrick Couvreur 2
1 Institut Lavoisier, University of Versailles, Versailles France, 2 Faculty of Pharmacy, University Paris XI, Chatenay Malabry France

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12:45 PM - HH2.6
Protein-Nanoparticle Conjugates As Neuroprotective Agents.

Vladimir Reukov 1 , Victor Maximov 1 , Alexey Vertegel 1
1 , Clemson University, Clemson, South Carolina, United States

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HH3: Advanced Biomaterials II
Session Chairs
Antonios Mikos
Monday PM, December 01, 2008
Room 310 (Hynes)

2:30 PM - HH3.1
Shape-memory Properties of Multiblock Copolymers Consisting of Poly(ω-pentadecalactone) Hard Segments and Crystallisable Poly(ε-caprolactone) Switching Segments.

Karl Kratz 1 2 , Ulrike Voigt 2 , Wolfgang Wagermaier 2 , Andreas Lendlein 1 2
1 , Center for Biomaterial Development and Berlin-Brandenburg Centre for Regenerative Therapies (BCRT), Teltow Germany, 2 , GKSS Forschungszentrum Geesthacht GmbH, Teltow Germany

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2:45 PM - HH3.2
Magnetron-Sputtered Zinc Doped Hydroxyapatite Thin Films for Orthopedic Applications.

Patrick Marti 1 , Serena Best 1 , Zoe Barber 1 , Roger Brooks 2 , Neil Rushton 2
1 Department of Materials Science & Metallurgy, University of Cambridge, Cambridge United Kingdom, 2 Department of Surgery, University of Cambridge, Cambridge United Kingdom

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3:15 PM - HH3.4
Novel Biologically-inspired KRSR and RGD Modified Rosette Nanotube Coatings on Orthopedic Implants.

Lijie Zhang 1 , Usha Hemraz 2 , Hicham Fenniri 2 , Thomas Webster 1
1 Engineering, Brown University, Providence, Rhode Island, United States, 2 National Institute for Nanotechnology and Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada

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3:30 PM - HH3.5
Activatable Nanoparticle-Tagged Perfluorocarbon Droplets for Medical Imaging.

Naomi Matsuura 1 , Ivan Gorelikov 1 , Ross Williams 1 , Kelvin Wan 1 , Siqi Zhu 1 , James Booth 2 , Peter Burns 1 , Kullervo Hynynen 1 , John Rowlands 1
1 Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada, 2 Molecular and Cellular Biology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

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3:45 PM - HH3.6
Maghemite Nanoparticles Embedded in a Silica Shell as Enhanced T2 Contrast Agent for MRI.

Elena Taboada 1 , Anna Roig 1 , Elisenda Rodriguez 2
1 Crystallography Dpt., Institut de Ciència de Materials de Barcelona (ICMAB-CSIC), Bellaterra Spain, 2 Center for Molecular Imaging Research, MGH-Harvard Medical Hospital, Boston, Massachusetts, United States

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4:00 PM - HH3: ADBIOMAT
BREAK

HH4: Drug Delivery Systems II Gene and Peptide Delivery
Session Chairs
Kathryn Uhrich
Monday PM, December 01, 2008
Room 310 (Hynes)

4:30 PM - **HH4.1
A Multilayered Approach to Surface-Mediated DNA Delivery.

David Lynn 1
1 Department of Chemical and Biological Engineering, University of Wisconsin - Madison, Madison, Wisconsin, United States

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5:00 PM - HH4.2
DNA Delivery Using pH-Sensitive Polymer Vesicles.

Hannah Lomas 1 , Irene Canton 1 , Marzia Massignani 1 , Adam Blanazs 2 , Steven Armes 2 , Andrew Lewis 3 , Giuseppe Battaglia 1
1 Biomaterials and Tissue Engineering Group, Department of Engineering Materials, The Kroto Research Institute, The University of Sheffield, Sheffield United Kingdom, 2 Department of Chemistry, The University of Sheffield, Sheffield United Kingdom, 3 , Biocompatibles UK Ltd, Farnham Business Park, Farnham, Surrey United Kingdom

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5:15 PM - HH4.3
Role of Shell Structure and Surface Chemistry in the Cytosolic Delivery of SiRNA, Proteins, and Viral Particles into Cells using Endosome-escaping Core-shell Nanoparticles.

Darrell Irvine 1 3 2 , Yuhua Hu 4 , Prabhani Atukorale 3 , Eun Chol Choi 1
1 Materials Sci. and Engineering, MIT, Cambridge, Massachusetts, United States, 3 Biological Engineering, MIT, Cambridge, Massachusetts, United States, 2 Koch Institute for Integrative Cancer Research, MIT, Cambridge, Massachusetts, United States, 4 Chemical Engineering, MIT, Cambridge, Massachusetts, United States

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5:30 PM - HH4.4
Polyelectrolyte Multilayer Drug Delivery of Antimicrobial Peptides.

Anita Shukla 1 , Robert Langer 1 , Paula Hammond 1
1 Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States

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5:45 PM - HH4.5
Nanostructured Ceramic Coatings for Drug Delivery.

Karin Dittmar 1 , Arnaud Tourvieille 1 2 , Laurent-Dominique Piveteau 2 , Heinrich Hofmann 1
1 Laboratory of Powder Technology, Ecole Polytechnique Fédérale de Lausanne, Lausanne Switzerland, 2 , Debiotech SA, Lausanne Switzerland

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HH5: Poster Session: Functional Materials and Drug Delivery Systems
Session Chairs
LinShu Liu
Tuesday AM, December 02, 2008
Exhibition Hall D (Hynes)

9:00 PM - HH5.1
Favorable Surface Adhesion Response of Electrodeposited Nano-hydroxyapatite on Ultrafine-grained (UFG)/nano-grained (NG) Austenitic Stainless Steel.

Sachin Mali 1 , Mahesh Somani 1 , L. Karjalainen 1 , Devesh Misra 1 , Sashank Nayak 1
1 Center for Structural and Functional Materials, University of Louisiana at Lafayette, Lafayette, Louisiana, United States

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9:00 PM - HH5.10
Synthesis of Magnetic Porous Hollow Silica Nanostructures for Drug Delivery.

Hui Ma 1 , Mark DeCoster 2 , James McNamara 2 , Daniela Caruntu 1 , Jianfeng Chen 3 , Charles O'Connor 1 , Weilie Zhou 1
1 AMRI/Chemistry, Advanced Materials Research Institute/UNO, New Orleans, Louisiana, United States, 2 Biomedical Engineering and Institute for Micromanufacturing , Louisiana Tech University, Ruston, Louisiana, United States, 3 Key Lab for Nanomaterials, Ministry of Educations,, Beijing University of Chemical Technology, Beijing China

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9:00 PM - HH5.11
Novel Superparamagnetic Iron Oxide Nanoparticles for a Multifunctional Nanomedicine Platform.

Oleh Taratula 1 3 , Ronak Savla 1 3 , Ipsit Pandya 1 , Andrew Wang 2 , Tamara Minko 3 4 , Huixin He 1 4
1 Chemistry, Rutgers, the State University of New Jersey, Newark, New Jersey, United States, 3 Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, New Jersey, United States, 2 , Ocean NanoTech, Fayetteville, Arizona, United States, 4 , Cancer Institute of New Jersey, New Brunswick, New Jersey, United States

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9:00 PM - HH5.12
Single File Diffusion of Protein Drugs through Cylindrical Nanochannel.

Seung Yun Yang 1 , Jeong-A Yang 2 , Sei Kwang Hahn 2 , Jin Kon Kim 1
1 Environmental Science & Engineering and Chemical Engineering, POSTECH, Pohang Korea (the Republic of), 2 Material Science & Engineering, POSTECH, Pohang Korea (the Republic of)

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9:00 PM - HH5.13
Bioinspired Design of Polymer Films for Controlled Release of Self-assembling Colloidal Aggregate Containing Sirolimus.

Hyung Il Kim 1 4 , Madoka Takai 2 4 , Tomohiro Konno 2 4 , Ryosuke Matsuno 2 4 , Jeong-Sun Seo 3 , Kazuhiko Ishihara 1 2 4
1 Department of Bioengineering, School of Engineering, The University of Tokyo, Tokyo Japan, 4 Center for NanoBio Integration (CNBI), The University of Tokyo, Tokyo Japan, 2 Department of Materials Engineering, School of Engineering, The University of Tokyo, Tokyo Japan, 3 Ilchun Genomic Medicine Institute, MRC and Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul Korea (the Republic of)

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9:00 PM - HH5.14
Effect of Polymer Adsorption on Crystallization of Small Organic Molecules.

Hyemin Choi 1 , Jonghwi Lee 1
1 Department of Chemical Engineering and Materials Science, Chung-Ang University, Seoul Korea (the Republic of)

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9:00 PM - HH5.15
Formulation Of A Hierarchically Designed Peptide Nucleic Acid Based DNA Delivery Construct.

Peter Millili 1 , Daniel Yin 3 , Haihong Fan 3 , Ulhas Naik 2 , Millicent Sullivan 3
1 Chemical Engineering, University of Delaware, Newark, Delaware, United States, 3 Pharmaceutical Sciences, Merck & Co., West Point, Pennsylvania, United States, 2 Biological Sciences, University of Delaware, Newark, Delaware, United States

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9:00 PM - HH5.16
IR Spectroscopy and DSC Studies of Binary Combinations of cis-6-Octadecenoic Acid and Octadecanoic Acid – Relevance to Stratum Corneum Permeation.

David Moore 3 , Eilidh Bedford 1 2 , Donald Koelmel 3 , Donna Laura 3
3 , ISP, Wayne, New Jersey, United States, 1 Performance Products, Cabot Corporation, Billerica, Massachusetts, United States, 2 , Unilever, Port Sunlight United Kingdom

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9:00 PM - HH5.17
Antisense Oligonucleotides Delivery to the Antigen Presenting Cells by using Schizophyllan.

Shinichi Mochizuki 1 , Jusaku Minari 1 , Mika Kasuga 1 , Yoshiyuki Adachi 2 , Kazuo Sakurai 1
1 , The University of Kitakyushu, Fukuoka Japan, 2 , Tokyo University of Pharmacy and Life Science, Hachioji, Tokyo Japan

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9:00 PM - HH5.18
Design, Synthesis, and Biological Functionality of a Modular Drug Delivery Platform.

Douglas Mullen 1 3 , Daniel McNerny 2 3 , Xue-min Cheng 3 , Alina Kotlyar 3 , Ankur Desai 3 , Istvan Majoros 3 , James Baker 3 , Mark Banaszak Holl 1 3 4
1 Macromolecular Science and Engineering Program, University of Michigan, Ann Arbor, Michigan, United States, 3 Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, Michigan, United States, 2 Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan, United States, 4 Department of Chemistry, University of Michigan, Ann Arbor, Michigan, United States

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9:00 PM - HH5.19
Layer-by-Layer Assembly of Block Copolymer Micelles for Applications in Drug Delivery from Surfaces.

Byeong-Su Kim 1 , Paula Hammond 1
1 Chemical Engineering, MIT, Cambridge, Massachusetts, United States

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9:00 PM - HH5.2
In-vitro Bioactivity and Mechanical Properties of a Novel Implantable Biomaterial: Nano-tricalcium Phosphate-silicone Rubber Nanostructured Composite.

Jinesh Shah 1 , Wah Wah Thein-Han 1 , Qiang Yuan 1 , Devesh Misra 1
1 Center for Structural and Functional Materials, University of Louisiana at Lafayette, Lafayette, Louisiana, United States

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9:00 PM - HH5.20
Self-Assembly of Genetically Engineered M13 Bacteriophage and Functional Polymers into Macroscopic Vesicular Membranes and Fibers.

Woo-Jae Chung 1 2 , Seung-Wuk Lee 1 2
1 Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States, 2 Bioengineering, UC Berkeley, Berkeley, California, United States

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9:00 PM - HH5.21
Synthesis and Characterization of Silica Particles as a Drug Delivery Vessel.

Sami Chanaa 1 , Hangning Chen 1 3 , Ben Estes 1 , John Larese 1 2
1 Chemistry, University of Tennessee, Knoxville, Tennessee, United States, 3 College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu, China, 2 College of Chemistry and Chemical Engineering, ORNL, Oak Ridge, Tennessee, United States

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9:00 PM - HH5.22
Structural Changes of Horse Cytochrome c in a Biomimetic System: AOT Reverse Micelles. A Molecular Modeling Study.

Stephane Abel 1 , Marcel Waks 2 , Msssimo Marchi 1
1 DSV/IBiTec-C/SB2SM, Commissairiat a l'energie atomique, Saclay France, 2 Laboratoire Imagerie Paramétrique, CNRS, LIP, UMR 7623, Université Pierre et Marie Curie Paris 6, Paris France

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9:00 PM - HH5.23
A Diagnostic Sensor using a Carbon Nanotube-polymer Composite for the Determination of Acetone in Aqueous and Urine Samples.

Gina Lein 2 , Kalathur Santhanam 1 2 , Lynn Fuller 3
2 Department of Chemistry, Rochester Institute of Technology, Rochester, New York, United States, 1 Center For Materials Science and Engineering, Rochester Institute of Technology, Rochester, New York, United States, 3 Microelectronics Engineering, Rochester Institute of Technology, Rochester, New York, United States

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9:00 PM - HH5.24
Biodegradable Microfluidic Scaffolds for Tissue Engineering from Amino Alcohol-based Poly(ester amide) Elastomers.

Jane Wang 1 2 3 , Christopher Bettinger 1 2 , Robert Langer 3 4 5 , Jeffrey Borenstein 2
1 Material Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States, 2 Biomedical Engineering Center, Charles Stark Draper Laboratory, Cambridge, Massachusetts, United States, 3 Program of Polymer Science and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States, 4 Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States, 5 Division of Health Sciences and Technology, Harvard-M.I.T., Cambridge, Massachusetts, United States

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9:00 PM - HH5.26
Synthesis, Characterization and Preliminary Testing of Mesoporous Silica Nanoparticles for Drug Delivery Application.

Elayaraja Muthuswamy 1 , Shantaraj Bhattarai 2 , David Oupicky 2 , Stephanie Brock 1 , Michal Brichacek 1
1 Chemistry, Wayne State University, Detroit, Michigan, United States, 2 Pharmaceutical Sciences, Wayne State University, Detroit, Michigan, United States

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9:00 PM - HH5.27
Covalent Tethering of Plasmid DNA for Substrate-Mediated Gene Delivery.

Kory Blocker 1 , Kristi Kiick 2 , Millicent Sullivan 1
1 Chemical Engineering, University of Delaware, Newark, Delaware, United States, 2 Materials Science and Engineering, University of Delaware, Newark, Delaware, United States

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9:00 PM - HH5.29
Solid Lipid Templating of Open-pore Microscaffolds.

Kristina Ambrosch 1 , Michaela Schulz-Siegmund 1 , Michael Hacker 1
1 Pharmaceutical Technology, University of Leipzig, Leipzig Germany

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9:00 PM - HH5.3
Peptide-based Polyurethane Elastomers as Tissue Engineering Scaffolds

Elizabeth Cosgriff-Hernandez 1 , Thomas Wilems 1 , Nick Sears 1
1 Biomedical Engineering, Texas A&M University, College Station, Texas, United States

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9:00 PM - HH5.30
Self-assembly of Comb-rod Dendritic Block Copolymers as Tunable Drug Delivery Systems.

Shujun Chen 1 , Paula Hammond 1
1 Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States

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9:00 PM - HH5.31
Anodzied Titanium For Local Drug Delivery.

Chang Yao 1 , Thomas Webster 1
1 , Brown University, Providence, Rhode Island, United States

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9:00 PM - HH5.32
Triterpene Saponin Glycosides Impact the Percutaneous Delivery of Water Soluble Drugs.

Christopher Pino 1 , Michael Scherer 1 , Chenxia Guan 2 , V. Shastri 1
1 Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, United States, 2 Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States

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9:00 PM - HH5.33
Design of a Bacteriophage for Targeted Delivery of an Antimicrobial Peptide.

Adam Hathorne 1 , Harry Bermudez 1
1 Polymer Science and Engineering, University of Massachusetts, Amherst, Amherst, Massachusetts, United States

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9:00 PM - HH5.34
Raman Spectroscopy of Defected Griseofulvin in Powders and Films.

Anna Zarow 1 , Bo Zhou 2 , William Wagner 1 , Rodolfo Pinal 2 , Zafar Iqbal 1
1 , New Jersey Institute of Technology, Newark, New Jersey, United States, 2 , Purdue University, West Lafayette, Indiana, United States

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9:00 PM - HH5.4
Functionally Graded Coatings for Wear Resistant Biomaterials: Characterization through Nanoindentation and Nanoscratch Tests.

Pasquale Vena 1 , Roberto Contro 1 , Dario Gastaldi 1 , Emanuele Bertarelli 1 , Carlo Bottani 2 , Marco Beghi 2 , Fabio di Fonzo 2 , Diego Tonini 2
1 Structural Engineering, Politecnico di Milano, Milano Italy, 2 Department of Chemistry, Materials and Chemical Engineering, Politecnico di Milano, Milano Italy

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9:00 PM - HH5.5
Electro-wetting and ArF Excimer Laser Induced Photochemical Surface Modification Formation of Hydrophilic and Hydrophobic Micro-domain Structure on IOL Surface for Blocking after Cataract.

Yuji Sato 1 , Kenji Kawai 2 , Mikio Sasou 3 , Hiroaki Ozaki 4 , Takeo Ooki 5 , Masataka Murahara 1
1 , Tokyo Institute of Technology, Tokyo Japan, 2 School of Medicine, Tokai University, Kanagawa Japan, 3 School of Medicine, University of Mie, Mie Japan, 4 School of Medicine, Fukuoka University, Fukuoka Japan, 5 School of Medicine, University of Tokushima, Tokushima Japan

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9:00 PM - HH5.6
Tailored Scaffolds from a Gelatin-based Polymer System: Influence of the Molecular Architecture on Material Properties.

Axel Neffe 1 2 , Giuseppe Tronci 2 , Martin Roessle 2 , Andreas Lendlein 1 2
1 , Centre for Biomaterial Development and Berlin-Brandenburg Centre for Regenerative Therapies (BCRT), Teltow Germany, 2 , GKSS Forschungszentrum Geesthacht GmbH, Teltow Germany

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9:00 PM - HH5.7
Controlled Actuation of Shape-Memory Polymer Networks by Application of Magnetic Field.

Muhammad Razzaq 1 , Marc Behl 1 , Karl Kratz 1 , Andreas Lendlein 1
1 Center for Biomaterial Development, Institute of Polymer Research, GKSS Forschungszentrum Geesthacht GmbH, Teltow Germany

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9:00 PM - HH5.8
Liquid Phase Deposition of Nanoporous Titania on Spatially Organized Poly(p-xylylene) Films.

Niranjan Malvadkar 1 , Melik Demirel 1
1 Engineering Science and Mechanics, Pennsylvania State University, University Park, Pennsylvania, United States

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9:00 PM - HH5.9
Active Cooperative Assemblies Towards Nanocomposites.

Muhammet Toprak 1 , Carmen Vogt 1 , Abhilash Sugunan 1
1 Functional Materials, Royal Institute of Technology, Stockholm Sweden

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HH6/DD3: Joint Poster Session: Materials in Tissue Engineering
Session Chairs
Elizabeth Orwin
V. Prasad Shastri
Tuesday AM, December 02, 2008
Exhibition Hall D (Hynes)

9:00 PM - HH6.1/DD3.1
Segmented Polyurethane Implants For Regeneration Of Esophagus.

Yerkesh Batyrbekov 1 , Nurzhan Bubeev 2 , Bulat Zhubanov 1
1 , Institute of Chemical Sciences, Almaty Kazakhstan, 2 , South Kazakhstan State Medicinal Academy, Chimkent Kazakhstan

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9:00 PM - HH6.10/DD3.10
In Situ Mineralization of Block Copolymer Hydrogels.

David Griffin 1 , Surita Bhatia 1
1 Chemical Engineering, University of Massachusetts, Amherst, Massachusetts, United States

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9:00 PM - HH6.11/DD3.11
Porous Hydroxyapatite/gelatin Scaffolds via Freeze-drying: the Effect of Bioceramic Nanoparticles on the Scaffold’s Microarchitecture and Properties.

Andrei Stanishevsky 1 , Sonda Sengupta 1 , Erin Ellis 1
1 , University of Alabama at Birmingham, Birmingham, Alabama, United States

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9:00 PM - HH6.12/DD3.12
Biomimetic Chitosan/nano-hydroxyapatite Composite Scaffolds for Bone Tissue Engineering.

Wah Wah Thein-Han 1 , Jinesh Shah 1 , Devesh Misra 1
1 Center for Structural and Functional Materials, University of Louisiana at Lafayette, Lafayette, Louisiana, United States

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9:00 PM - HH6.13/DD3.13
Towards Functional Biomaterials: Elucidating Design Principles of Enzyme Activated Hydrogelation.

Andrew Hirst 1 2 , Rein Ulijn 1 2 3
1 School of Materials and Manchester Interdisciplinary Biocentre, University of Manchester, Manchester, Lancashire, United Kingdom, 2 School of Materials, University of Manchester, Manchester United Kingdom, 3 School of Chemistry, University of Strathclyde, Glasgow United Kingdom

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9:00 PM - HH6.14/DD3.14
Hybrid Biomaterials with Tunable Elastic Modulus Through Sol-gel Functionalization of Peptidic Hydrogels.

Aysegul Altunbas 1 , Nikhil Sharma 1 , Radhika Nagarkar 2 , Joel Schneider 2 , Darrin Pochan 1
1 Materials Science & Engineering, University of Delaware, Newark, Delaware, United States, 2 Department of Chemistry & Biochemistry, University of Delaware, Newark, Delaware, United States

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9:00 PM - HH6.16/DD3.16
Novel Composite Biomaterials Made from Resilin and Cellulose.

Shaul Lapidot 1 , Mara Dekel 1 , Sigal Meirovitch 1 , Sigal Roth 2 , Daniel Siegel 2 , Noa Lapidot 2 , Oded Shoseyov 1 2
1 The Faculty of Agriculture, Food and Environmental Quality Sciences, The Hebrew University of Jerusalem, Israel, Rehovot Israel, 2 , CollPlant ltd 2 Pekeris St. POB 2310 , Rehovot Israel

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9:00 PM - HH6.17/DD3.17
Modified Alginate for Biomedical Applications.

Soumitra Choudhary 1 , Surita Bhatia 1
1 Chemical Engineering, University of Massachusetts, Amherst, Amherst, Massachusetts, United States

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9:00 PM - HH6.19/DD3.19
Hyaluronic Acid-gelatin Nanofibrous Scaffold Produced by Electrospinning of Their Aqueous Solution for Tissue Engineering Applications.

Ying Liu 1 , Richard Clark 2 , Lei Huang 3 , Miriam Rafailovich 1
1 Department of Materials Science and Engineering, SUNY at Stony Brook, Stony Brook, New York, United States, 2 Department of Biomedical Engineering, SUNY at Stony Brook, Stony Brook, New York, United States, 3 Department of Physics and Astronomy, SUNY at Stony Brook, Stony Brook, New York, United States

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9:00 PM - HH6.2/DD3.2
Synthetic Platelets’ Role in Vascular Trauma and Their Interactions with Platelets.

James Bertram 1 , Nolan Flynn 2 , Erin Lavik 1
1 Biomedical Engineering, Yale University, New Haven, Connecticut, United States, 2 Chemistry, Wellesley College, Wellesley, Massachusetts, United States

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9:00 PM - HH6.20/DD3.20
Iron Oxide Magnetic Nanoparticles for Treating Bone Diseases.

Nhiem Tran 1 , Thomas Webster 2
1 Department of Physics, Brown University, Providence, Rhode Island, United States, 2 Division of Engineering and Orthopaedics, Brown University, Providence, Rhode Island, United States

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9:00 PM - HH6.21/DD3.21
Drug Loaded Polypyrrole Coatings on Titanium for Supporting Bone Growth and Inhibiting Fibrosis.

Sirinrath Sirivisoot 1 , Rajesh Pareta 1 , Thomas Webster 2
1 Division of Engineering, Brown University, Providence, Rhode Island, United States, 2 Division of Engineering and Orthopaedics, Brown University, Providence, Rhode Island, United States

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9:00 PM - HH6.22/DD3.22
Surface Modification Effect of Carbon Nanotubes-based Scaffolds on Human Embryonic Stem Cells Adhesion and Differentiation.

Tzu-I Chao 1 , Wei-Chun Chin 1 , Jennifer Lu 1 , Fang Lu 1
1 , University of California at Merced, Merced, California, United States

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9:00 PM - HH6.23/DD3.23
Mechanical Behavior of Individual Bovine Marrow-derived Stem Cells Undergoing Chondrogenesis.

BoBae Lee 1 , Paul Kopesky 2 , Eric Vanderploeg 3 , Bodo Kurz 6 , Christine Ortiz 1 , Alan Grodzinsky 2 4 5
1 Materials Science and Engineering, MIT, Cambridge, Massachusetts, United States, 2 Biological Engineering, MIT, Cambridge, Massachusetts, United States, 3 Center for Biomedical Engineering, MIT, Cambridge, Massachusetts, United States, 6 Anatomisches Institut, Christian-Albrechts-Universität zu Kiel, Kiel Germany, 4 Electrical Engineering and Computer Science, MIT, Cambridge, Massachusetts, United States, 5 Mechanical Engineering, MIT, Cambridge, Massachusetts, United States

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9:00 PM - HH6.25/DD3.25
Cell Patterning Using Nanostructured Surfaces.

ChiungWen Kuo 1 , Jau-Ye Shiu 1 , Peilin Chen 1
1 Research Center for Applied Sciences, Academia Sinica, Taipei Taiwan

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9:00 PM - HH6.26/DD3.26
Neural and Glial Cell Adhesion and Proliferation on Carbon Nanotube and Nanoparticle Zinc Oxide Polymer Composites.

Justin Seil 1 , Thomas Webster 1
1 , Brown University, Providence, Rhode Island, United States

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9:00 PM - HH6.27/DD3.27
Photocurable Biodegradable Elastomers as Tissue Engineering Scaffolds.

Cody Schoener 1 , Christopher Perry 1 , Ranjini Murthy 1 , Melissa Grunlan 1
1 Biomedical Engineering, Texas A & M University, College Station, Texas, United States

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9:00 PM - HH6.28/DD3.28
Cytotoxicity and Biological Effects of Functional Nanomaterials Delivered to Various Cell Lines.

Meena Mahmood 1
1 Applied Science, UALR, Nanotechnology Center, Little Rock, Arkansas, United States

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9:00 PM - HH6.29/DD3.29
Platelet Response on Poly (lactide-co-glycolic-acid) (PLGA) Film with Nano-structured Fillers.

Li Buay Koh 1 , Isabel Rodriguez 2 , Subbu S Venkatraman 1
1 School of Materials Science and Engineering, Nanyang Technological University, Singapore Singapore, 2 , Institute of Materials Research & Engineering, A*STAR (Agency for Science, Technology and Research), Singapore Singapore

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9:00 PM - HH6.3/DD3.3
Skin-external Device Integration using Expandable Cationic Poly(DMAA-co-AMTAC) Hydrogels.

Antonio Peramo 1 , Joong Hwan Bahng 2 , Cynthia Marcelo 3 , Nicholas Kotov 2 1 4 , David Martin 1 4 5
1 Materials Science and Engineering, University of Michigan, Ann Arbor, Michigan, United States, 2 Chemical Engineering, University of Michigan, Ann Arbor, Michigan, United States, 3 Surgery, University of Michigan, Ann Arbor, Michigan, United States, 4 Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, United States, 5 Macromolecular Science and Engineering, University of Michigan, Ann Arbor, Michigan, United States

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9:00 PM - HH6.30/DD3.30
Designing an Equivalent of the Corneal Extracellular Matrix by Investigating Corneal Fibroblast Response to Aligned Collagen Scaffolds.

Donna Phu 1 , Lindsay Wray 1 , Elizabeth Orwin 1
1 Engineering and Biology, Harvey Mudd College, Claremont, California, United States

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9:00 PM - HH6.31/DD3.31
Bone Tissue Induction, using a BC-PCL Composite Scaffold Material.

Maria Cortes 1 , Filipe A. F. Macedo 1 , Ruben Sinisterra 2 , Alfonso Gala-Garcia 1
1 Restorative Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil, 2 Chemistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

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