Meetings & Events

2012 MRS Spring Meeting Logo

2012 MRS Spring Meeting & Exhibit

April 9-13, 2012 | San Francisco
Meeting Chairs: Lara A. Estroff, Jun Liu, Kornelius Nielsch, Kazumi Wada

Symposium VV : Nanomedicine for Molecular Imaging and Therapy

2012-04-10   Show All Abstracts

Symposium Organizers

Xiaoyuan (Shawn) Chen, National Institute of Biomedical Imaging and Bioengineering National Institutes of Health
Jinwoo Cheon, Yonsei University
Mansoor Amiji, Northeastern University
Shuming Nie, Emory University
VV2: Nanomedicine for Molecular Imaging and Therapy II
Session Chairs
Xiaoyuan Chen
Tuesday PM, April 10, 2012
Marriott, Golden Gate, Salon B

2:30 AM - *VV2.1
Nanocomposite Design of Advanced Biomaterials

Jackie Y. Ying 1

1Institute of Bioengineering and Nanotechnology Singapore Singapore

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3:00 AM - VV2.2
Spatio-temporally Concerting Gold Nanoparticle Conjugates for Highly Synergistic Cancer Therapy

Jutaek Nam 1 Wan-Geun La 2 Sekyu Hwang 1 Yeong Su Ha 3 Nokyoung Park 4 Nayoun Won 1 Sungwook Jung 5 Suk Ho Bhang 2 Yoon-Ji Ma 2 Yong-Min Cho 2 Min Jin 2 Eun Kyung Wang 3 Sang Geol Kim 6 Jong-Min Kim 4 So-Hye Cho 7 Jeongsoo Yoo 3 Byung-Soo Kim 2 Sungjee Kim 1 5

1Pohang University of Science amp; Technology Pohang Republic of Korea2Seoul National University Seoul Republic of Korea3Kyungpook National University Daegu Republic of Korea4Samsung Electronics Yongin Republic of Korea5Pohang University of Science amp; Technology Pohang Republic of Korea6Kyungpook National University Daegu Republic of Korea7Korea Institute of Science and Technology Seoul Republic of Korea

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3:15 AM - VV2.3
In vivo Imaging, Cell Targeting, and Controlled Drug Release of Fe3O4 Nanospheres

Donglu Shi 1 4 Chris Huth 2 Feng Wang 2 Giovanni Pauletti 3

1Tongji University Shanghai China2University of Cincinnati Cincinnati USA3University of Cincinnati Cincinnati USA4University of Cincinnati Cincinnati USA

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3:30 AM - VV2.4
Exploiting the Gold Nanorod-Protein Corona Complex for Delivery and Remote Triggered Release of Small Molecular Therapeutics

James Kah 1 Christin Grabinski 2 Angel Zubieta 3 Saber Hussain 2 Kimberly Hamad-Schifferli 1 4

1Massachusetts Institute of Technology Cambridge USA2Air Force Research Laboratory, Wright Patterson AFB Dayton USA3The University of Texas at Austin Austin USA4Massachusetts Institute of Technology Cambridge USA

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3:45 AM - VV2.5
Microfluidic Device for High Efficiency DNA Extraction from Single Cells

Harvey C Tian 1 2 Christopher B Wallin 2 Juraj Topolancik 2 Benjamin R Cipriany 3 Jaime J Benitez 2 David R Latulippe 2 Patrick J Murphy 4 Paul D Soloway 5 Harold G Craighead 2

1Cornell University Ithaca USA2Cornell University Ithaca USA3Cornell University Ithaca USA4Cornell University Ithaca USA5Cornell University Ithaca USA

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4:00 AM -
BREAK

4:30 AM - VV2.6
Cholesterol-containing Polymeric Micellar Nanoparticles for Targeted Delivery of Hydrophobic Anticancer Drugs with Rigid Structures

Ashlynn Lee 1 Shrinivas Venkataraman 1 Syamilah Sirat 1 Shujun Gao 1 James L Hedrick 2 Yi-Yan Yang 1

1Institute of Bioengineering and Nanotechnology Singapore Singapore2IBM Almaden Research Center San Jose USA

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4:45 AM - VV2.7
Direct Translocation of Cell-Penetrating Peptides (CPPs) across Lipid Bilayers

Andrew Wang 1 Nicholas Melosh 1

1Stanford Unviversity Palo Alto USA

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5:00 AM - VV2.8
A Novel Biocompatible Nanoparticle Platform for Simultaneous Delivery of Hydrophobic, Hydrophilic Chemotherapeutic Drugs, siRNA and Gold Clusters for Cancer Therapy and Imaging

Hai Wang 1 Yan Wu 1 Guangjun Nie 1

1National Center for Nanoscience and Technology, China Beijing China

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5:15 AM - VV2.9
Superheated Nanoemulsions as Stimulus-responsive Ultrasound Contrast Agents for Cancer Detection and Imaging

Andrew P. Goodwin 1 Alan C Toledo 1 Zhe C Wu 2 Matthew A Nakatsuka 1 Jennifer N Cha 1 Sadik C Esener 1

1University of California, San Diego La Jolla USA2University of California, San Diego San Diego USA

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VV1: Nanomedicine for Molecular Imaging and Therapy I
Session Chairs
Xiaoyuan Chen
Tuesday AM, April 10, 2012
Marriott, Golden Gate, Salon B

9:15 AM - VV1.1
A Closer Look at Two-photon Absorption in Colloidal Gold Nanorods

Joanna Olesiak Banska 1 Radoslaw Kolkowski 1 Marta Gordel 1 Katarzyna Matczyszyn 1 Marek Samoc 1

1Wroclaw University of Technology Wroclaw Poland

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9:30 AM - VV1.2
Engineering Fluorescent Gold Nanoparticles for In vivo Pharmacokinetic Profiling and Tumor Imaging

Leo Chou 1 2 Warren Chan 1 2

1University of Toronto Toronto Canada2University of Toronto Toronto Canada

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9:45 AM - *VV1.3
Designed Synthesis of Uniform-sized Iron Oxide Nanoparticles for New MRI Contrast Agents

Taeghwan Hyeon 1 Nohyun Lee 1 Byung Hyo Kim 1 Mihyun Park 1 Daishun Ling 1 Soo Hong Yi 1 Youjin Lee 1

1Seoul National University Seoul Republic of Korea

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10:15 AM - VV1.4
Conjugated Polymer Nanoparticles for Small Interfering RNA Delivery

Joongho Moon 1 Eladio Mendez 1 Youri Lee 1

1Florida International Univ Miami USA

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10:45 AM -
BREAK

11:15 AM - *VV1.6
Multifunctional Mesoporous Silica Nanoparticles for Targeting, Imaging and Drug Delivery

Jeffrey I Zink 1

1UCLA Los Angeles USA

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11:45 AM - VV1.7
Nanoparticle Size and PEG Density Controls Serum Protein Adsorption and Macrophage Uptake

Carl D Walkey 1 4 Jonathan B Olsen 2 3 4 Hongbo Guo 2 3 4 Andrew Emili 2 3 4 Warren Chan 1 4

1University of Toronto Toronto Canada2University of Toronto Toronto Canada3University of Toronto Toronto Canada4University of Toronto Toronto Canada

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12:00 PM - VV1.8
Gold Nanoparticle-based Assay for Acetylcholinesterase in Cerebrospinal Fluid of Transgenic Mice with Alzheimerrsquo;s Disease

Dingbin Liu 1 Xingyu Jiang 1 Zhuo Wang 1

1National Center for Nanoscience and Technology, China Beijing China

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12:15 PM - VV1.9
Metal Chelating Crosslinkers and Their Application in Hydrogels and Hydrogel Nanoparticles for Non-invasive Imaging

Minnie Chan 1 Adah Almutairi 1

1University of California San Diego San Diego USA

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12:30 PM - VV1.10
Hybrid Lipid-Polymer Nanoparticles for Safe and Effective Delivery of Small Interfering RNA

Jinjun Shi 1 2 Alexander R Votruba 1 Xiaoyang Xu 1 2 Zeyu Xiao 1 2 Robert Langer 2 Bruce R Zetter 3 Omid C Farokhzad 1

1Brigham and Women's Hospital, Harvard Medical School Boston USA2Massachusetts Institute of Technology Cambridge USA3Childrenrsquo;s Hospital Boston, Harvard Medical School Boston USA

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2012-04-11   Show All Abstracts

Symposium Organizers

Xiaoyuan (Shawn) Chen, National Institute of Biomedical Imaging and Bioengineering National Institutes of Health
Jinwoo Cheon, Yonsei University
Mansoor Amiji, Northeastern University
Shuming Nie, Emory University
VV4: Nanomedicine for Molecular Imaging and Therapy IV
Session Chairs
Xiaoyuan Chen
Wednesday PM, April 11, 2012
Marriott, Golden Gate, Salon B

2:30 AM - *VV4.1
Use of High Throughput Discovery at the Nano/Bio Interface to Improve Nanotherapeutics and Nanosafety

Andre Nel 1

1UCLA David Geffen School of Medicine Los Angeles USA

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3:00 AM - VV4.2
Cancer Cell Targeting by a Novel Coating Material for Carbon Nanotubes

Magdalena Swierczewska 1 2 Ki Young Choi 2 Seulki Lee 2 Xiaoyuan Chen 2

1Stony Brook University Stony Brook USA2NIBIB/NIH Bethesda USA

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3:15 AM - VV4.3
SERS Biotags (SBTs) for the Quantitative Ratiometric Discrimination between Noncancerous and Cancerous Prostate Cells

Alessia Pallaoro 1 Gary Braun 2 Martin Moskovits 1

1University of California Santa Barbara Santa Barbara USA2Sanford Burnham Medical Research Institute - UCSB Santa Barbara USA

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3:30 AM - VV4.4
Study of Cellular Reponse to Functional Silicon Nanowires Using Nonlinear Optical Imaging

Chen Yang 1 Weixia Zhang 1 Ji-xin Cheng 2

1Purdue University West Lafayette USA2Purdue University West Lafayette USA

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3:45 AM - VV4.5
Bacteriophage MS2 Virus-Like Particles (VLPs) - A Combinatorial Platform for Affinity Selection and Targeted Delivery of Therapeutics

Mekensey D Buley 1 Katharine Epler 5 6 Carlee Ashley 2 8 Cheryl Willman 8 9 Stephan Grupp 10 Jeffrey Brinker 4 3 8 Walker Wharton 9 David Peabody 7 David Padilla 5

1University of New Mexico Albuquerque USA2Sandia National Labs Livermore USA3Sandia National Labs Albuquerque USA4University of New Mexico Albuquerque USA5University of New Mexico Albuquerque USA6University of New Mexico Albuquerque USA7University of New Mexico Health Sciences Center Albuquerque USA8University of New Mexico Health Sciences Center Albuquerque USA9University of New Mexico Health Sciences Center Albuquerque USA10The Childrens' Hospital of Philadelphia Philadelphia USA

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4:00 AM -
BREAK

4:30 AM - *VV4.6
Supramolecular Structures Self-assembled from Engineered Block Copolymers for Theranostics Nanodevice

Kazunori Kataoka 1

1University of Tokyo Tokyo Japan

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5:00 AM - VV4.7
Biodegradable Polymeric Nanoparticles for Gene Delivery: The Effect of Polymer Structures on Nanoparticle Stability and Transfection Efficiency

Zhe Zhang 3 Michael Keeney 1 Fan Yang 1 2

1Stanford University Stanford USA2Stanford University Stanford USA3Tsinghua University Beijing China

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5:15 AM - VV4.8
Selective Release from Gold Nanorods for Applications in Nanomedicine

Kimberly Hamad-Schifferli 1

1MIT Cambridge USA

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5:30 AM - VV4.9
Improved Cellular Uptake of Drug-containing Polymer Nanoparticles through Surface Charge-Stabilization

Sai Archana Krovi 1 Elden P Swindell 1 Thomas V Orsquo;Halloran 1 SonBinh T Nguyen 1

1Northwestern University Evanston USA

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5:45 AM - VV4.10
Targeted Delivery of Therapeutic RNA to Virally-infected Host Cells via Nanoporous Particle-supported Lipid Bilayers (Protocells)

Carlee Ashley 1 Katharine Epler 2 Oscar Negrete 1 Eric Carnes 2 3

1Sandia National Labs Livermore USA2University of New Mexico Albuquerque USA3University of New Mexico Albuquerque USA

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VV5: Poster Session
Session Chairs
Wednesday PM, April 11, 2012
Marriott, Yerba Buena, Salons 8-9

9:00 AM - VV5.10
Targeted Delivery of Therapeutic Agents to Hepatocellular Carcinoma via Nanoporous Particle-supported Lipid Bilayers

Katharine Elizabeth Epler 3 5 Dan C Wilkinson 3 Robert E Castillo 3 David P Padilla 3 Trevin Heisey 3 Brian S Wilkinson 3 Natalie Johannes 3 Cameron Burgard 3 Jason Townson 3 Jeffrey Brinker 2 4 6 Carlee Ashley 1 4 Eric C Carnes 2 4

1Sandia National Laboratories Livermore USA2University of New Mexico Albuquerque USA3University of New Mexico Albuquerque USA4University of New Mexico Health Sciences Center Albuquerque USA5Sandia National Laboratories Albuquerque USA6Sandia National Laboratories Albuquerque USA

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9:00 AM - VV5.11
Glutathione-Responsive Silica Nanocarriers with Cyclodextrin Gatekeeper

Chulhee Kim 1 Jeonghun Lee 1 Minji Kim 1 Hyunjeong Kim 1 Hyemi Lee 2 Heon Joo Park 2

1Inha University Incheon Republic of Korea2Inha University Incheon Republic of Korea

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9:00 AM - VV5.12
Effectiveness of microRNA-21 Inhibitor Gene Therapy Combined with Temozolomide for Glioblastoma Depend on the Time and Sequence Influence

Yu Ren 1 Xiaomin Qian 2 Zhendong Shi 3 Xuan Zhou 4 Lixia Long 2 Xubo Yuan 2 Zhenduo Cui 2 Chunsheng Kang 3 Chaoyong Liu 1

1Tianjin Medical University Tianjin China2Tianjin University Tianjin China3Tianjin Medical University General Hospital Tianjin China4Tianjin Cancer Hospital amp; Institute Tianjin China

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9:00 AM - VV5.13
A New TEM Imaging Technique for Liposomes

Sarah Hoppe 1 Darryl Sasaki 2 David Nackashi 3 John Damiano 3 Khalid Hattar 1

1Sandia National Laboratories Albuquerque USA2Sandia National Laboratories Livermore USA3Protochips, Inc. Raleigh USA

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9:00 AM - VV5.14
Luminescent Silicon Carbide Quantum Dots Prepared by Reactive Bonding and Subsequent Wet Chemical Etching: Characterization and Potential Applications

David Beke 1 Zsolt Szekrenyes 1 Istvan Balogh 1 Adam Gali 1 2

1Research Institute for Solid State Physics and Optics Budapest Hungary2Budapest University of Technology and Economics Budapest Hungary

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9:00 AM - VV5.15
Multifunctional Nanoparticles as Imaging Probes and Cooperative Therapeutic Agents in Tumor Cells

Prasad Subramaniam 1 Birju P Shah 1 Ki-Bum Lee 1

1Rutgers University Piscataway USA

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9:00 AM - VV5.16
Multifunctional Polypeptide-based Nanocarriers for Targeted Drug and Gene Delivery to Tumor Cells

Prasad Subramaniam 1 Dipti N Barman 1 Cheoljin Kim 1 Ki-Bum Lee 1

1Rutgers University Piscataway USA

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9:00 AM - VV5.17
Enhancement of Gene Delivery Efficiency for Human Neural Stem Cells by Magnetically Guided Penetration

Eunmi Kim 1 Ji-Seon Oh 1 Ik-Sung Ahn 1 Kook In Park 2 Jae-Hyung Jang 1

1Yonsei University Seoul Republic of Korea2Yonsei University College of Medicine Seoul Republic of Korea

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9:00 AM - VV5.18
Preparation of Dendrimer Porphyrin-containing Multilayered Hollow Nanocapsules for Combination Cancer Therapy

Won-Gun Koh 1 Kyung Jin Son 1 Tae Geuk Lim 1

1Yonsei Univ Seoul Republic of Korea

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9:00 AM - VV5.19
Polyethylene Oxide-polystyrene Oxide Triblock Copolymers as Biological-responsive Nanocarriers

Silvia Barbosa 1 Adriana Cambon 1 Ana Rey-Rico 2 Jose Brea 3 Isabel M Loza 3 Stephen G Yeates 4 Carmen Alvarez-Lorenzo 2 Angel Concheiro 2 Pablo Taboada 1 Victor Mosquera 1

1Universidad de Santiago de Compostela Santiago de Compostela Spain2Universidad de Santiago de Compostela Santiago de Compostela Spain3Universidad de Santiago de Compostela Santiago de Compostela Spain4University of Manchester Manchester United Kingdom

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9:00 AM - VV5.2
Ordered Arrays of Single Elongated Chromatin Fragments: Towards the Mapping and Analysis of Multiple Epigenetic Marks

Aline Cerf 1 Harvey C Tian 1 Benjamin R Cipriany 2 Jaime J Benitez 1 Harold G Craighead 1

1Cornell University Ithaca USA2Cornell University Ithaca USA

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9:00 AM - VV5.20
Comparison and Correlation between PET and Fluorescence Dynamic Imaging by Using a Dual-labeled Cyclic RGD Analog

Lei Zhu 1 Ning Guo 1 Seulki Lee 1 Xiaoyuan Chen 1

1NIH Bethesda USA

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9:00 AM - VV5.21
NMR Force Microscopy of Ammonium Sulfate with 12mu;m Resolution

Isaac Vicente Manzanera 1 John T Markert 1

1University of Texas Austin USA

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9:00 AM - VV5.22
Gold-silver Alloy Nanoparticle Interaction with Optically Active Proteins

Don N Ho 1 Andy Blaeser 2 Arto Nurmikko 2 Shouheng Sun 1

1Brown University Providence USA2Brown University Provid USA

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9:00 AM - VV5.23
Organocatalytic Polymerization of Cyclic Esters and Carbonates for the Formation of Unimolecular Delivery Vehicles

Amanda C Engler 1 Daniel J Coady 1 Yi Yan Yang 2 James L Hedrick 1

1IBM San Jose USA2Institute of Bioengineering and Nanotechnology The Nanos Singapore

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9:00 AM - VV5.25
Gadolinium-Phosphate Complexes with High Relaxivities Immobilized on Particles for Magnetic Resonance Imaging (MRI)

Alexandra K Duncan 1 Piper J Klemm 2 Christopher Landry 1

1University of Vermont Burlington USA2University of California Berkeley USA

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9:00 AM - VV5.26
Effect of Single-walled Carbon Nanotubes Entry into Mammalian Cells

Howard H Chen 1 Bradly Baer 2 Christopher S Evans 2 Hannah M Ponek 3 Sara Y Choung 2 Michelle Chen 3

1Massachusetts General Hospital, Harvard Medical School Charlestown USA2Point Loma Nazarene University San Diego USA3Point Loma Nazarene University San Diego USA

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9:00 AM - VV5.27
Enhanced Cargo Capacity of Therapeutic Agents by Encapsulation in a Protocell Nanoparticle

Dan Charles Wilkinson 1 Brian S Wilkinson 1 Trevin Heisey 1 Cameron Burgard 1 C. Jeffrey Brinker 2 1 Eric Carnes 1

1University of New Mexico Albuquerque USA2Sandia National Labs Albuquerque USA

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9:00 AM - VV5.28
Biocompatability of Mesoporous Silica Nanoparticles for Theranostic Applications

Kennedy Dai Nguyen 1 Gayatri Premasekharan 1 Jacob Petersen 1 Ian Donahue 1 Henry Forman 2 3 Valerie Leppert 1

1University of California, Merced Merced USA2University of California, Merced Merced USA3University of Southern California Los Angeles USA

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9:00 AM - VV5.3
Diagnostic Applications of Graphene Oxide/DNA Nano-Complex

Won Ho Kong 1 Ki Su Kim 1 Ho-Sang Jung 1 Sei Kwang Hahn 1

1Pohang University of Science and Technology (POSTECH) Pohang Republic of Korea

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9:00 AM - VV5.30
Evaluation of Long Circulating Nanoparticles Based on Amphiphilic Peptide-polymer Conjugates as Potential Therapeutic Carriers

Nikhil Dube 1 He Dong 1 Jessica Shu 1 Jai Woong Seo 4 Katherine Ferrara 4 Ting Xu 1 2 3

1University of California, Berkeley Berkeley USA2University of Caliofrnia, Berkeley Berkeley USA3Lawrence Berkeley National Laboratory Berkeley USA4University of California, Davis Davis USA

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9:00 AM - VV5.4
Ultrasmall and Uniform Gold Nanoparticles for Cell Uptake Studies with Cell Penetrating Peptides

Alioscka Sousa 1 Jeffrey Morgan 1 April Adams 1 Patrick Brown 1 Michael Kruhlak 2 Richard Leapman 1

1National Institutes of Health Bethesda USA2National Institutes of Health Bethesda USA

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9:00 AM - VV5.5
Chitosan/TPP Nanoparticles as a Gene Delivery Agent for Tumor Suppressant p53

Gaojun Liu 1 Xia Zhao 2 Kevin G Yager 3 Michael Hadjiargyrou 2 Yizhi Meng 1 4

1Stony Brook University Stony Brook USA2Stony Brook University Stony Brook USA3Brookhaven National Laboratory Upton USA4Stony Brook University Stony Brook USA

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9:00 AM - VV5.6
Ceramic Nanophosphors for over-1000-nm (OTN) NIR Bioimaging

Kohei Soga 1 2 Hioshi Hyodo 1 2 Hidehiro Kishimoto 2 3

1Tokyo Univ. of Science Noda Japan2Tokyo Univ. of Science Noda Japan3Tokyo Univ. of Science Noda Japan

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9:00 AM - VV5.7
Surface Modification of Quantum Dots for Efficient Cell Labeling

Jungheon Kwag 1 Nayoun Won 2 Sungjee Kim 1 2

1POSTECH Pohang Republic of Korea2POSTECH Pohang Republic of Korea

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9:00 AM - VV5.8
pH-induced Aggregation of Very Small Gold Nanoparticles for Photothermal Cancer Therapy

Sekyu Hwang 1 Jutaek Nam 1 Sungjee Kim 1

1POSTECH Pohang Republic of Korea

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9:00 AM - VV5.9
Stabilizing Organic Nanoparticles by Helix-bundle Forming Peptide-polymer Conjugates

He Dong 1 Jessica Y Shu 1 Nikhil Dube 1 Jai W Seo 2 Katherine W Ferrara 2 Ting Xu 1

1UC Berkeley Berkeley USA2UC Davis Davis USA

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VV3: Nanomedicine for Molecular Imaging and Therapy III
Session Chairs
Xiaoyuan Chen
Wednesday AM, April 11, 2012
Marriott, Golden Gate, Salon B

9:15 AM - *VV3.1
Porphysome Nanomedicine: A New Paradigm for Cancer Imaging and Therapy

Gang Zheng 1

1University of Toronto Toronto Canada

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9:45 AM - VV3.2
Fabrication of Composite Silica Nano Test Tubes for Delivery Applications

Fatih Buyukserin 1 2 Sevket Tolga Camli 1

1Gazi University Nanomedicine Research Center Ankara Turkey2TOBB University of Economics and Technology Ankara Turkey

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10:00 AM - VV3.3
Hydroxypropylcellulose Coated Mesoporous Silica Nanoparticles Loaded with Magnetic Clusters for Chemohyperthermia in Pancreatic Adenocarcinoma

Dong-Hyun Kim 1 Jodi R Nicolai 1 Daniel Procissi 1 Weiguo Li 1 Yang Guo 1 Zhuoli Zhang 1 Reed A Omary 1 2 3 Andrew C Larson 1 2 3

1Northwestern Feinberg School of Medicine Chicago USA2Northwestern University Chicago USA3Robert H. Lurie Comprehensive Cancer Center, Northwestern Memorial Hospital Chicago USA

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10:15 AM - VV3.4
Cytosolic Delivery of Dynamic Nanoscale Probes of Physical States in Live Cells

Brett A. Helms 1 Aaron E Albers 1 Andrea R Bayles 1 Dev S Chahal 1 Harvey S Chahal 1 Patrick M McBride 1 Teresa E Pick 1 Bruce E Cohen 1 Caroline A Ajo-Franklin 1

1Lawrence Berkeley National Laboratory Berkeley USA

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10:30 AM - VV3.5
Targeted Nanoparticle-Supported Lipid Bilayers for the Treatment of Blood Cancers

Eric Carnes 1 Carlee Ashley 2 Katharine Epler 1 Dan Wilkinson 1 Robert Castillo 1 Trevin Heisey 1 Cameron Burgard 1 Walker Wharton 1 C. Jeffrey Brinker 2 1 Cheryl Willman 1

1University of New Mexico Albuquerque USA2Sandia National Labs Albuquerque USA

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