5:00 PM - SM02.04.05
Late News: Electrosynthesized ZnO Nanoantimicrobials for Cultural Heritage Applications
Margherita Izzi1,Maria Sportelli1,Roberto Gristina2,Rosaria Anna Picca1,Nicola Cioffi1
University of Bari Aldo Moro1,Institute of Nanotechnology, National Research Council of Italy (CNR-NANOTEC), c/o Department of Chemistry2
The employment of bioactive nanomaterials is one of the most strategical approach to fight antimicrobial resistance and biofilm formation. In particular, metal and metal oxide nanoparticles with controlled ion release can show a noteworthy antimicrobial activity . The use of zinc oxide (ZnO) nanostructures for these purposes is continuously expanding, due to its biocompatibility and low toxicity. In our research group we are exploring electrochemical strategies for the preparation of ZnO nanostructures based on the use of a sacrificial Zn anode in an aqueous electrolytic bath  as alternative approach to conventional methods. By tuning the synthesis parameters and selecting the proper stabilizer, spheroidal and flower-like ZnO nanostructures are synthesized. Particularly, poly-sodium-4-styrenesulfonate (PSS), cetyltrimethylammonium bromide (CTAB), benzyl-hexadecyl-dimethylammonium chloride (BAC) and poly-diallyl-(dimethylammonium) chloride (PDDA) have been tested as capping agents [3–5]. Novel hybrid coatings were developed by dispersing the as-synthesized ZnO into commercially-available consolidating agents. The nanostructured coatings were deposited on stone monuments as multifunctional films, providing antimicrobial and consolidating properties [6,7]. More recently, flower-like nanostructures have been successfully tested against Bacillus subtilis as a Gram-positive model microorganism . Morphological analyses carried out on the ZnO-based nanomaterials will be presented. The combination of UV–Vis, FTIR and XPS spectroscopies afforded for the univocal assessment of the material composition as a function of different processing and deposition conditions. A critical comparison of the different materials will be presented, outlining the effects of the stabilizer.
1. Sportelli, M.C.; Picca, R.A.; Cioffi, N. Nano-Antimicrobials Based on Metals. In Novel Antimicrobial Agents and Strategies; Wiley-Blackwell, 2014; pp. 181–218 ISBN 978-3-527-67613-2.
2. Izzi, M.; Sportelli, M.C.; Ditaranto, N.; Picca, R.A.; Innocenti, M.; Sabbatini, L.; Cioffi, N. Pros and Cons of Sacrificial Anode Electrolysis for the Preparation of Transition Metal Colloids: A Review. ChemElectroChem 2020, 7, 386–394, doi:10.1002/celc.201901837.
3. Picca, R.A.; Sportelli, M.C.; Hötger, D.; Manoli, K.; Kranz, C.; Mizaikoff, B.; Torsi, L.; Cioffi, N. Electrosynthesis and Characterization of ZnO Nanoparticles as Inorganic Component in Organic Thin-Film Transistor Active Layers. Electrochimica Acta 2015, 178, 45–54, doi:10.1016/j.electacta.2015.07.122.
4. Picca, R.A.; Sportelli, M.C.; Lopetuso, R.; Cioffi, N. Electrosynthesis of ZnO Nanomaterials in Aqueous Medium with CTAB Cationic Stabilizer. J. Sol-Gel Sci. Technol. 2017, 81, 338–345, doi:10.1007/s10971-016-4268-9.
5. Sportelli, M.C.; Picca, R.A.; Izzi, M.; Palazzo, G.; Gristina, R.; Innocenti, M.; Torsi, L.; Cioffi, N. ZnO Nanostructures with Antibacterial Properties Prepared by a Green Electrochemical-Thermal Approach. Nanomaterials 2020, 10, 473, doi:10.3390/nano10030473.
6. Ditaranto, N.; Werf, I.D. van der; Picca, R.A.; Sportelli, M.C.; Giannossa, L.C.; Bonerba, E.; Tantillo, G.; Sabbatini, L. Characterization and Behaviour of ZnO-Based Nanocomposites Designed for the Control of Biodeterioration of Patrimonial Stoneworks. New J. Chem. 2015, 39, 6836–6843, doi:10.1039/C5NJ00527B.
7. van der Werf, I.D.; Ditaranto, N.; Picca, R.A.; Sportelli, M.C.; Sabbatini, L. Development of a Novel Conservation Treatment of Stone Monuments with Bioactive Nanocomposites. Herit. Sci. 2015, 3, 29, doi:10.1186/s40494-015-0060-3.