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2011 MRS Fall Meeting & Exhibit

November 28-December 2, 2011 | Boston

Meeting Chairs: Cammy R. Abernathy, Paul V. Braun, Masashi Kawsaki, Kathyn J. Wahl

Symposium JJ : Nanofunctional Materials, Nanostructures, and Nanodevices for Cancer Applications

2011-11-28   Show All Abstracts

Symposium Organizers

Piotr Grodzinski National Cancer Institute
Scott Manalis Massachusetts Institute of Technology
Sonke Svenson Cerulean Pharma Inc.
Xing-Jie Liang National Center for Nanoscience and Technology of China
Wenbin Lin University of North Carolina-Chapel Hill
JJ1: Detection of Biomarkers and Biological Response
Session Chairs
Piotr Grodzinski
Monday AM, November 28, 2011
Room 203 (Hynes)

10:00 AM - **JJ1.1
Nanotheranostics for Cancer: Targeted Nanoparticles for Tumor Imaging, Image-Guided Drug Delivery and Light Induced Therapy.

Paras Prasad 1 2 , Tymish Ohulchanskyy 1
1 Institute for Lasers, Photonics and Biophotonics, State University of New York at Buffalo, Buffalo, New York, United States, 2 Chemistry, State University of New York at Buffalo, Buffalo, New York, United States

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10:30 AM - JJ1.2
Novel Multifunctional Nanocarriers Capable of In Vivo Rapidly Controlled Drug Release for MR Imaging and Targeted Epilepsy Therapy.

Hsin-Yang Huang 1
1 Department of Materials Sciences and Engineering, National Chiao Tung University, Hsin Chu, TAIWAN, Taiwan

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10:45 AM - JJ1.3
``AND'' Logic T1-T2 Nanoparticles for Fault-Free MR Imaging.

Jin-sil Choi 1 , Tae-hyun Shin 1 , Dongwon Yoo 1 , Ho-Taek Song 2 , Eung Yeop Kim 2 , Jinwoo Cheon 1
1 Dept. of Chemistry, Yonsei University, Seoul Korea (the Republic of), 2 Department of Radiology , College of Medicine, Yonsei University, Seoul Korea (the Republic of)

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11:00 AM - JJ1.4
Quantum-Dot-Decorated Enzyme Nanocapsules for Cancer Imaging and Therapeutics.

Juanjuan Du 1 , Ming Yan 1 , Titiana Segura 1 , Yi Tang 1 , Yunfeng Lu 1
1 Department of Chemical and Biomolecular Engineering, UCLA, Los Angeles, California, United States

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11:15 AM -
break

11:30 AM - **JJ1.5
Magnetic Nanoparticles for Theranostics and Cell Actuations.

Jinwoo Cheon 1
1 , Yonsei University, Seoul Korea (the Republic of)

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12:00 PM - JJ1.6
Magnetic Nanoparticles as MRI Contrast Agents and for Selective Targeting of Cells.

Wolfgang Tremel 1 , Thomas Schladt 1 , Bahar Nakhjavan 1 , Kerstin Koll 1 , Heiko Bauer 1 , Oskar Koehler 1 , Isabell Schick 1 , Anna Schilmann 1 , Muhammad Tahir 1 , Filipe Natalio 1 , Peter Bluemler 2 , Kerstin Muennemann 3
1 Institut für Anorganische Chemie, Johannes Gutenberg-Universität, Mainz Germany, 2 Institut für Physik, Johannes Gutenberg-Universität, Mainz Germany, 3 , Max Planck-Institut für Polymerforschung, Mainz Germany

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12:15 PM - JJ1.7
Modulating the Luminescence of Upconverting Nanoparticles Using Dithienylethene Photoswitches for Biolabeling Applications.

John-Christopher Boyer 1 , Carl-Johan Carling 1 , Neil Branda 1
1 Chemistry, Simon Fraser University, Burnaby, British Columbia, Canada

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12:30 PM - JJ1.8
Incorporation of Quantum-Dots with Mesoporous Silica Nanoparticles for Intracellular Targeting and In Vivo Images.

Po-Jung Chen 1 , Shang-Hsiu Hu 2 , San-Yuan Chen 3 , Dean-Mo Liu 4
1 , National Chiao Tung University, Hsinchu Taiwan, 2 , National Chiao Tung University, Hsinchu Taiwan, 3 , National Chiao Tung University, Hsinchu Taiwan, 4 , National Chiao Tung University, Hsinchu Taiwan

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JJ2: Imaging and In-vivo Detection Using Nanoparticles
Session Chairs
Scott Manalis
Monday PM, November 28, 2011
Room 203 (Hynes)

2:30 PM - **JJ2.1
Multiplex Wash-Free Magneto-Nanosensors for Cancer Diagnostics and Drug Development.

Shan Wang 1
1 Materials Science and Engineering, Stanford University, Stanford, California, United States

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3:00 PM - JJ2.2
Quantitative Analysis of Multiple Urinary Biomarkers of Carcinoid Tumors through Gold-Nanoparticle-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry.

Tsung-Rong Kuo 1 4 , Jinn-Shiun Chen 2 , Yu-Chen Chi 1 , Chia-Yi Tsai 3 , Cho-Chun Hu 3 , Chia-Chun Chen 1 4
1 Chemistry, Natl Taiwan Normal University, Taipei Taiwan, 4 Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei Taiwan, 2 Division of Colorectal Surgery, Chang Gung University, Taoyuan Taiwan, 3 Natural Science Education, National Taitung University, Taitung Taiwan

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3:15 PM - JJ2.3
High-Performance Electrochemical Sensing of Cancerous Protease (Legumain) Using Nanoelectrode Arrays.

Lateef Uddin Syed 1 , Luxi Zhang 1 , Allan Prior 1 , Jianwei Liu 1 , Duy Hua 1 , Jun Li 1
1 Chemistry, Kansas State University, Manhattan, Kansas, United States

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3:30 PM - JJ2.4
Investigating Receptor-Ligand Interactions on Tunable Nanostructured, Biofunctionalized Surfaces under Flow.

Sebastian Kruss 1 2 , Luise Erpenbeck 3 , Michael Schoen 3 , Joachim Spatz 1 2
1 , MPI for Intelligent Systems, Stuttgart Germany, 2 Physical Chemistry, Heidelberg University , Heidelberg Germany, 3 Department of Dermatology, Göttingen University, Heidelberg Germany

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3:45 PM - JJ2.5
Exploring the Impact of Cell Mechanics on Cancer Progression with the Microfluidic Optical Stretcher.

Mareike Zink 1 , Franziska Wetzel 1 , Anatol Fritsch 1 , Steve Pawlizak 1 , Tobias Kiessling 1 , Kenechukwu Nnetu 1 , Lars-Christian Horn 2 , Michael Hoeckel 3 , Josef Kaes 1
1 Soft Matter Physics Division, University of Leipzig, Leipzig Germany, 2 Institute of Pathology, University of Leipzig, Leipzig Germany, 3 Department of Obstetrics and Gynecology, University of Leipzig, Leipzig Germany

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4:00 PM - *
break

4:30 PM - **JJ2.6
Implanted Diagnostic Devices.

Michael Cima 1 2
1 Department of Materials Science & Engineering, Massachusetts Inst. of Technology, Cambridge, Massachusetts, United States, 2 The David H. Koch Institute for Integrative Cancer Research, Massachusetts Inst. of Technology, Cambridge, Massachusetts, United States

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5:00 PM - JJ2.7
Sensing Energy Metabolism In Vivo – Visualization of Lipolytic Enzyme Activity by Real-Time MRI Using Nanocrystals.

Oliver Bruns 1 2 , Alexander Bartelt 3 , Ulrich Tromsdorf 5 , Horst Weller 5 , Moungi Bawendi 1 , Rudolph Reimer 2 , Barbara Freund 3 , Peter Nielsen 3 , Joerg Heeren 3 , Harald Ittrich 4
1 Chemistry, MIT, Cambridge, Massachusetts, United States, 2 Microtechnology and Electron Microscopy, Heinrich-Pette-Institute, Hamburg, Hamburg, Germany, 3 Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Hamburg, Germany, 5 Chemistry, University of Hamburg, Hamburg, Hamburg, Germany, 4 Diagnostic and Interventional Radiology Department and Clinic, University Medical Center Hamburg-Eppendorf, Hamburg, Hamburg, Germany

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5:15 PM - JJ2.8
Development of Efficient Quantum Dot Antibody(QD-Ab) Conjugation to Label Single Cells In Vivo.

Hee-Sun Han 1 , Jayeeta Bhaumik 2 , Walid Kamoun 2 , Becky Chen 2 , Dan Duda 2 , Rakesh Jain 2 , Moungi Bawendi 2
1 Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States, 2 Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States

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5:30 PM - JJ2.9
Rapid, Label-Free, Electrical Whole Blood Bioassay Based on Nanobiosensor System.

Hsiao-Kang Chang 1 , Chongwu Zhou 1
1 Electrical Engineering, Univ. of Southern California, Los Angeles, California, United States

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2011-11-29   Show All Abstracts

Symposium Organizers

Piotr Grodzinski National Cancer Institute
Scott Manalis Massachusetts Institute of Technology
Sonke Svenson Cerulean Pharma Inc.
Xing-Jie Liang National Center for Nanoscience and Technology of China
Wenbin Lin University of North Carolina-Chapel Hill
JJ5: Poster Session - Nanofunctional Materials, Nanostructures, and Nanodevices for Cancer Applications
Session Chairs
Piotr Grodzinski
Wenbin Lin
Tuesday PM, November 29, 2011
Exhibition Hall C (Hynes)

1:00 AM -
JJ5.50 TRANSFERRED TO JJ3.8

JJ3: Bio-Nano-Material for Cancer I
Session Chairs
Xing-Jie Liang
Tuesday AM, November 29, 2011
Room 203 (Hynes)

9:30 AM - **JJ3.1
Quantum Dots Capable of Efficient Translocation through Nuclear Pore Complexes.

Jan Liphardt 1
1 Physics, UC Berkeley, Berkeley, California, United States

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10:00 AM - JJ3.2
New Route for the Synthesis of Multifunctional Gold Nanorods - Surgical Technology for Spectroscopy, Imaging and Therapy.

Clement Barriere 1 , Pilar Garcia-Allende 1 , Ji Qi 1 , Daniel Elson 1
1 Surgery and Cancer, Imperial College London, London United Kingdom

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10:15 AM - JJ3.3
Selective Triggered Release from Gold Nanorods.

Kimberly Hamad-Schifferli 1
1 Biological and Mechanical Engineering, MIT, Cambridge, Massachusetts, United States

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10:30 AM - JJ3.4
Hydrodynamic Fractionation of Finite Size Gold Nanoparticle Clusters for Biomedical Applications.

De-Hao Tsai 1 , Tae Joon Cho 1 , Frank DelRio 1 , Julian Taurozzi 1 , Michael Zachariah 1 2 , Vincent Hackley 1
1 Materials Measurement Laboratory, National Institute of Standards and Technology, Gaithersburg, Maryland, United States, 2 Departments of Mechanical Engineering and Chemistry, University of Maryland, College Park, Maryland, United States

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10:45 AM - JJ3.5
Force Spectroscopy Mapping of the Mechanical Properties of Polyethylene Glycol Brushes on Gold Substrates.

Gheorghe Stan 1 , Frank DelRio 1 , Robert MacCuspie 1 , Robert Cook 1
1 Ceramics Division, National Institute of Standards and Technology, Gaithersburg, Maryland, United States

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11:00 AM - *
break

11:30 AM - **JJ3.6
Nanomaterial Characterization: Methodologies for Successful Drug Development.

Anil Patri 1
1 , Nanotechnology Characterization Laboratory, SAIC-Frederick, Inc., Frederick, Maryland, United States

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12:00 PM - JJ3.7
Acid- and Urea-Functionalized Polycarbonate Micellar Nanoparticles Stabilized by Hydrogen-Bonding for Anticancer Drug Delivery.

Amalina Attia 1 , Jeremy Tan 1 , Chuan Yang 1 , James Hedrick 2 , Yi-Yan Yang 1
1 , Institute of Bioengineering and Nanotechnology, Singapore Singapore, 2 , IBM Almaden Research Center, San Jose, California, United States

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12:15 PM - JJ3.8
Iron Carbide Nanoparticles Elaboration: Composition, Size Control and Air Stability. Applications to Magnetic Hyperthermia.

Anca Meffre 1 , Boubker Mehdaoui 1 , Sebastien Lachaize 1 , Julian Carrey 1 , Pier Fazzini 1 , Marc Respaud 1 , Bruno Chaudret 1
1 , INSA toulouse, Toulouse France

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12:30 PM - JJ3.9
Impact of Gold Nanoparticle Size and Surface Chemistry on Diffusion in Poly(Ethylene Glycol) Hydrogels.

Stephanie Hume 1 , Kavita Jeerage 1
1 Materials Reliability Division, National Institute of Standards and Technology, Boulder, Colorado, United States

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12:45 PM - JJ3.10
Gold Nanoparticles with Tuning Near Infrared Absorption via Reaction of HAuCl4 and Na2S2O3 for Low Power Photothermal Cancer Therapy.

Guandong Zhang 1 , Jacek Jasinski 2 , Dhruvinkumar Patel 1 , Kurtis James 1 , Xinghua Sun 1 , Andre Gobin 1
1 Bioengineering Department, University of Louisville, Louisville, Kentucky, United States, 2 Conn Center for Renewable Energy Research, University of Louisville, Louisville, Kentucky, United States

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JJ4: Nanotechnology-Enabled Drug Delivery and Therapy
Session Chairs
Sonke Svenson
Tuesday PM, November 29, 2011
Room 203 (Hynes)

2:30 PM - **JJ4.1
Improving Delivery and Efficacy of Nano-Therapeutics by Normalizing Tumor Microenvironment.

Rakesh Jain 1
1 , Harvard Medical School - Massachusetts General Hospital, Boston, Massachusetts, United States

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3:00 PM - JJ4.2
Polymeric Backpacks for Cell-Mediated Drug Delivery.

Jonathan Gilbert 1 , Aaron Anselmo 3 , Albert Swiston 2 , Nishit Doshi 3 , Samir Mitragotri 3 , Robert Cohen 1 , Michael Rubner 2
1 Chemical Engineering, MIT, Cambridge, Massachusetts, United States, 3 Chemical Engineering, University of California Santa Barbara, Santa Barbara, California, United States, 2 Materials Science and Engineering, MIT, Cambridge, Massachusetts, United States

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